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          System Message

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          LOADING ...
          See other ALOX12 SIRNA Assays ›
          Gene Symbol:
          ALOX12
          Gene Name:
          arachidonate 12-lipoxygenase, 12S type
          Gene Aliases:
          12-LOX, 12S-LOX, LOG12
          Chromosome Location:
          Chr.17: 6993791 - 7010736 on Build GRCh38
          UniGene ID:
          Hs.654431
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s1274

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ALOX12
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000697.2 NP_000688.2 3 420
          XM_011523780.2 XP_011522082.1 3 2694
          GenBank mRNA BC069557.1 - 3 398 7262463
          M35418.1 - 3 408
          M58704.1 - 3 400
          M62982.1 - 3 420

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          More Information


          Panther Classification:

          Molecular Function -

          oxygenase

          Gene Ontology Categories:

          Function(s) Process(es)

          movement of cell or subcellular component
          aging
          positive regulation of cell proliferation
          positive regulation of endothelial cell migration
          positive regulation of gene expression
          negative regulation of muscle cell apoptotic process
          arachidonic acid metabolic process
          lipoxygenase pathway
          fatty acid oxidation
          positive regulation of cell growth
          positive regulation of cell migration
          superoxide anion generation
          negative regulation of apoptotic process
          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
          linoleic acid metabolic process
          positive regulation of endothelial cell differentiation
          positive regulation of angiogenesis
          positive regulation of cell adhesion
          positive regulation of vasodilation
          positive regulation of smooth muscle cell proliferation
          hepoxilin metabolic process
          hepoxilin biosynthetic process
          positive regulation of mitochondrial depolarization
          establishment of skin barrier
          cellular response to lipid
          reactive oxygen species metabolic process
          negative regulation of platelet aggregation
          leukotriene A4 metabolic process
          lipoxin metabolic process
          lipoxin A4 biosynthetic process
          lipoxin B4 biosynthetic process
          arachidonate 12-lipoxygenase activity
          iron ion binding
          protein binding
          linoleate 13S-lipoxygenase activity
          oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
          hepoxilin-epoxide hydrolase activity
          hepoxilin A3 synthase activity

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