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          System Message

          OKCancel
          LOADING ...
          See other ADAM17 SIRNA Assays ›
          Gene Symbol:
          ADAM17
          Gene Name:
          ADAM metallopeptidase domain 17
          Gene Aliases:
          ADAM18, CD156B, CSVP, NISBD, NISBD1, TACE
          Chromosome Location:
          Chr.2: 9488486 - 9555820 on Build GRCh38
          UniGene ID:
          Hs.404914
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s13718
          Validated

          Purification
          Size
          Availability Inventoried
          Catalog # 4390824
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ADAM17
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_003183.5 NP_003174.3 3 517
          XM_011510375.2 XP_011508677.1 3 536
          XM_011510376.2 XP_011508678.1 3 485
          XM_017004785.1 XP_016860274.1 3 533
          XM_017004786.1 XP_016860275.1 2 205
          GenBank mRNA AK289829.1 - 3 452
          BC062687.1 - 3 471
          BC136783.1 - 3 379 9020773
          BC146658.1 - 3 489
          CN258241.1 - 3 487
          GQ402545.1 - 3 485
          U69611.1 - 3 416
          U69612.1 - 3 424
          U86755.1 - 3 465
          U92649.1 - 3 466

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          More Information


          Matching Taqman Gene Expression Assay:


          Hs00234224_m1

          Panther Classification:

          Molecular Function -

          protease

          Gene Ontology Categories:

          Function(s) Process(es)

          response to hypoxia
          positive regulation of protein phosphorylation
          neutrophil mediated immunity
          germinal center formation
          positive regulation of leukocyte chemotaxis
          proteolysis
          membrane protein ectodomain proteolysis
          cell adhesion
          epidermal growth factor receptor signaling pathway
          Notch signaling pathway
          Notch receptor processing
          positive regulation of cell proliferation
          positive regulation of T cell chemotaxis
          B cell differentiation
          positive regulation of cell growth
          positive regulation of cell migration
          positive regulation of transforming growth factor beta receptor signaling pathway
          negative regulation of transforming growth factor beta receptor signaling pathway
          membrane protein intracellular domain proteolysis
          positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
          response to lipopolysaccharide
          positive regulation of chemokine production
          regulation of mast cell apoptotic process
          T cell differentiation in thymus
          tumor necrosis factor-mediated signaling pathway
          cell adhesion mediated by integrin
          wound healing, spreading of epidermal cells
          epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
          response to drug
          positive regulation of epidermal growth factor-activated receptor activity
          spleen development
          cell motility
          defense response to Gram-positive bacterium
          PMA-inducible membrane protein ectodomain proteolysis
          positive regulation of cellular component movement
          response to high density lipoprotein particle
          metalloendopeptidase activity
          Notch binding
          interleukin-6 receptor binding
          integrin binding
          protein binding
          metallopeptidase activity
          zinc ion binding
          SH3 domain binding
          PDZ domain binding

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