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          System Message

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          LOADING ...
          See other HMGCR SIRNA Assays ›
          Gene Symbol:
          HMGCR
          Gene Name:
          3-hydroxy-3-methylglutaryl-CoA reductase
          Gene Aliases:
          LDLCQ3
          Chromosome Location:
          Chr.5: 75336334 - 75362101 on Build GRCh38
          UniGene ID:
          Hs.628096
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s141

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: HMGCR
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000859.2 NP_000850.1 19, 20 2776
          NM_001130996.1 NP_001124468.1 18, 19 2617
          XM_011543357.1 XP_011541659.1 19, 20 2927
          XM_011543358.1 XP_011541660.1 19, 20 2814
          XM_011543359.1 XP_011541661.1 18, 19 2768
          GenBank mRNA AK292892.1 - 19, 20 2707
          AK296499.1 - 19, 20 2931
          AK299655.1 - 6, 7 855
          AK312437.1 - 18, 19 2620
          AY429543.1 - 3, 4 450
          BC033692.1 - 18, 19 2553 5212903
          M11058.1 - 19, 20 2670

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          More Information


          Panther Classification:

          Molecular Function -

          oxidoreductase reductase metabolite interconversion enzyme

          Gene Ontology Categories:

          Function(s) Process(es)

          cholesterol biosynthetic process
          ubiquinone metabolic process
          aging
          response to nutrient
          isoprenoid biosynthetic process
          visual learning
          negative regulation of striated muscle cell apoptotic process
          positive regulation of cardiac muscle cell apoptotic process
          coenzyme A metabolic process
          positive regulation of stress-activated MAPK cascade
          negative regulation of MAP kinase activity
          myoblast differentiation
          response to ethanol
          negative regulation of vasodilation
          positive regulation of skeletal muscle tissue development
          positive regulation of smooth muscle cell proliferation
          protein tetramerization
          oxidation-reduction process
          negative regulation of wound healing
          negative regulation of insulin secretion involved in cellular response to glucose stimulus
          positive regulation of ERK1 and ERK2 cascade
          hydroxymethylglutaryl-CoA reductase (NADPH) activity
          protein binding
          hydroxymethylglutaryl-CoA reductase activity
          protein homodimerization activity
          coenzyme binding
          protein phosphatase 2A binding
          NADPH binding

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