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          System Message

          OKCancel
          LOADING ...
          See other BRCA1 SIRNA Assays ›
          Gene Symbol:
          BRCA1
          Gene Name:
          BRCA1, DNA repair associated
          Gene Aliases:
          BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53
          Chromosome Location:
          Chr.17: 43044295 - 43125483 on Build GRCh38
          UniGene ID:
          Hs.194143
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s224682

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: BRCA1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_007294.3 NP_009225.1 18, 19 5427
          NM_007297.3 NP_009228.2 17, 18 5335
          NM_007298.3 NP_009229.2 17, 18 1902
          NM_007299.3 NP_009230.2 18, 19 2077
          NM_007300.3 NP_009231.2 19, 20 5490
          NR_027676.1 18, 19 5331
          GenBank mRNA AF005068.1 - 18, 19 5296
          AY751490.1 - 17, 18 5195
          BC072418.1 - 18, 19 2077
          BC115037.1 - 19, 20 5395 7961446
          DQ333386.1 - 3, 4 269
          DQ363751.1 - 6, 7 770
          JN686490.1 - 17, 18 5195
          U14680.1 - 18, 19 5314
          U64805.1 - 17, 18 1883
          U68041.1 - 4, 5 305

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          More Information


          Panther Classification:

          Molecular Function -

          ubiquitin-protein ligase protein modifying enzyme

          Gene Ontology Categories:

          Function(s) Process(es)

          double-strand break repair via homologous recombination
          DNA double-strand break processing
          DNA synthesis involved in DNA repair
          strand displacement
          DNA replication
          postreplication repair
          double-strand break repair
          double-strand break repair via nonhomologous end joining
          regulation of gene expression by genetic imprinting
          transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          regulation of transcription from RNA polymerase III promoter
          fatty acid biosynthetic process
          apoptotic process
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          chromosome segregation
          centrosome cycle
          brain development
          response to nutrient
          intrinsic apoptotic signaling pathway in response to DNA damage
          dosage compensation by inactivation of X chromosome
          response to ionizing radiation
          positive regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          protein ubiquitination
          protein sumoylation
          androgen receptor signaling pathway
          chromosome breakage
          positive regulation of protein ubiquitination
          G2 DNA damage checkpoint
          response to estradiol
          negative regulation of intracellular estrogen receptor signaling pathway
          positive regulation of protein import into nucleus, translocation
          positive regulation of histone acetylation
          negative regulation of histone acetylation
          regulation of cell proliferation
          regulation of apoptotic process
          chordate embryonic development
          response to estrogen
          regulation of DNA methylation
          negative regulation of fatty acid biosynthetic process
          positive regulation of DNA repair
          positive regulation of angiogenesis
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of centriole replication
          positive regulation of histone H3-K4 methylation
          negative regulation of histone H3-K4 methylation
          negative regulation of histone H3-K9 methylation
          positive regulation of histone H3-K9 methylation
          protein autoubiquitination
          positive regulation of histone H4-K20 methylation
          positive regulation of cell cycle arrest
          cellular response to tumor necrosis factor
          cellular response to indole-3-methanol
          protein K6-linked ubiquitination
          regulation of signal transduction by p53 class mediator
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of reactive oxygen species metabolic process
          positive regulation of histone H3-K9 acetylation
          positive regulation of histone H4-K16 acetylation
          DNA binding
          chromatin binding
          damaged DNA binding
          transcription coactivator activity
          RNA binding
          ubiquitin-protein transferase activity
          protein binding
          zinc ion binding
          tubulin binding
          ligase activity
          enzyme binding
          ubiquitin protein ligase binding
          transcription regulatory region DNA binding
          androgen receptor binding

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