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          System Message

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          LOADING ...
          See other HFE SIRNA Assays ›
          Gene Symbol:
          HFE
          Gene Name:
          hemochromatosis
          Gene Aliases:
          HFE1, HH, HLA-H, MVCD7, TFQTL2
          Chromosome Location:
          Chr.6: 26087281 - 26096216 on Build GRCh38
          UniGene ID:
          Hs.233325
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s230495

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

          LOADING...
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          siRNA Details

          Gene Symbol: HFE
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000410.3 NP_000401.1 5 1124
          NM_001300749.1 NP_001287678.1 5 1124
          NM_139003.2 NP_620572.1 4 806
          NM_139004.2 NP_620573.1 4 848
          NM_139006.2 NP_620575.1 5 1082
          NM_139007.2 NP_620576.1 4 860
          NM_139008.2 NP_620577.1 4 818
          NM_139009.2 NP_620578.1 5 1055
          NM_139010.2 NP_620579.1 3 584
          NM_139011.2 NP_620580.1 2 308
          XM_011514543.2 XP_011512845.1 5 1086
          GenBank mRNA AF079407.1 - 5 958
          AF079408.1 - 4 736
          AF079409.1 - 4 694
          AF115265.1 - 5 975
          AF144242.1 - 4 811
          AF149804.1 - 4 690
          AJ249335.1 - 5 1055
          AJ249336.1 - 4 860
          AJ249337.1 - 4 848
          AJ249338.1 - 2 308
          AJ250635.1 - 3 584
          AK300933.1 - 5 968
          AY205604.1 - 4 725
          BC074721.2 - 6 1004 30915171
          BC117201.1 - 5 999 40125752
          BC117203.1 - 5 999 40125754
          JN375755.1 - 2 182
          JN375756.1 - 2 181
          JN375757.1 - 2 172
          JN375758.1 - 2 181
          JN375759.1 - 2 187
          U60319.1 - 5 1185

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          More Information


          Panther Classification:

          Molecular Function -

          major histocompatibility complex protein

          Gene Ontology Categories:

          Function(s) Process(es)

          antigen processing and presentation of peptide antigen via MHC class I
          negative regulation of T cell antigen processing and presentation
          negative regulation of T cell cytokine production
          protein complex assembly
          cellular iron ion homeostasis
          acute-phase response
          immune response
          female pregnancy
          response to iron ion
          cellular response to iron ion starvation
          positive regulation of gene expression
          positive regulation of pathway-restricted SMAD protein phosphorylation
          antigen processing and presentation
          BMP signaling pathway
          positive regulation of protein binding
          negative regulation of proteasomal ubiquitin-dependent protein catabolic process
          hormone biosynthetic process
          positive regulation of receptor-mediated endocytosis
          iron ion homeostasis
          multicellular organismal iron ion homeostasis
          cellular response to iron ion
          positive regulation of peptide hormone secretion
          liver regeneration
          iron ion import into cell
          negative regulation of receptor binding
          positive regulation of receptor binding
          positive regulation of ferrous iron import into cell
          negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
          positive regulation of ferrous iron binding
          positive regulation of transferrin receptor binding
          response to iron ion starvation
          regulation of protein localization to cell surface
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          negative regulation of receptor activity
          positive regulation of receptor activity
          negative regulation of CD8-positive, alpha-beta T cell activation
          antigen binding
          receptor binding
          protein binding
          beta-2-microglobulin binding
          co-receptor binding
          peptide antigen binding
          transferrin receptor binding

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