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          System Message

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          LOADING ...
          See other HFE SIRNA Assays ›
          Gene Symbol:
          HFE
          Gene Name:
          hemochromatosis
          Gene Aliases:
          HFE1, HH, HLA-H, MVCD7, TFQTL2
          Chromosome Location:
          Chr.6: 26087281 - 26096216 on Build GRCh38
          UniGene ID:
          Hs.233325
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s230496

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

          LOADING...
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          siRNA Details

          Gene Symbol: HFE
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000410.3 NP_000401.1 5 1097
          NM_001300749.1 NP_001287678.1 5 1097
          NM_139003.2 NP_620572.1 4 779
          NM_139004.2 NP_620573.1 4 821
          NM_139006.2 NP_620575.1 5 1055
          NM_139007.2 NP_620576.1 4 833
          NM_139008.2 NP_620577.1 4 791
          NM_139009.2 NP_620578.1 5 1028
          NM_139010.2 NP_620579.1 3 557
          NM_139011.2 NP_620580.1 2 281
          XM_011514543.2 XP_011512845.1 5 1059
          GenBank mRNA AF079407.1 - 5 931
          AF079408.1 - 4 709
          AF079409.1 - 4 667
          AF109385.1 - 1 347
          AF115265.1 - 5 948
          AJ249335.1 - 5 1028
          AJ249336.1 - 4 833
          AJ249337.1 - 4 821
          AJ249338.1 - 2 281
          AJ250635.1 - 3 557
          AK300933.1 - 5 941
          AY205604.1 - 4 698
          BC074721.2 - 6 977 30915171
          BC117201.1 - 5 972 40125752
          BC117203.1 - 5 972 40125754
          JN375755.1 - 2 155
          JN375756.1 - 2 154
          JN375757.1 - 2 145
          JN375758.1 - 2 154
          JN375759.1 - 2 160
          U60319.1 - 5 1158

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          More Information


          Panther Classification:

          Molecular Function -

          major histocompatibility complex protein

          Gene Ontology Categories:

          Function(s) Process(es)

          antigen processing and presentation of peptide antigen via MHC class I
          negative regulation of T cell antigen processing and presentation
          negative regulation of T cell cytokine production
          protein complex assembly
          cellular iron ion homeostasis
          acute-phase response
          immune response
          female pregnancy
          response to iron ion
          cellular response to iron ion starvation
          positive regulation of gene expression
          positive regulation of pathway-restricted SMAD protein phosphorylation
          antigen processing and presentation
          BMP signaling pathway
          positive regulation of protein binding
          negative regulation of proteasomal ubiquitin-dependent protein catabolic process
          hormone biosynthetic process
          positive regulation of receptor-mediated endocytosis
          iron ion homeostasis
          multicellular organismal iron ion homeostasis
          cellular response to iron ion
          positive regulation of peptide hormone secretion
          liver regeneration
          iron ion import into cell
          negative regulation of receptor binding
          positive regulation of receptor binding
          positive regulation of ferrous iron import into cell
          negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
          positive regulation of ferrous iron binding
          positive regulation of transferrin receptor binding
          response to iron ion starvation
          regulation of protein localization to cell surface
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          negative regulation of receptor activity
          positive regulation of receptor activity
          negative regulation of CD8-positive, alpha-beta T cell activation
          antigen binding
          receptor binding
          protein binding
          beta-2-microglobulin binding
          co-receptor binding
          peptide antigen binding
          transferrin receptor binding

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          Host server : magellan-search-green-55658555d6-bznxf:80/100.66.77.153:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline