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          System Message

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          LOADING ...
          See other DNMT1 SIRNA Assays ›
          Gene Symbol:
          DNMT1
          Gene Name:
          DNA (cytosine-5-)-methyltransferase 1
          Gene Aliases:
          ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI
          Chromosome Location:
          Chr.19: 10133344 - 10195135 on Build GRCh38
          UniGene ID:
          Hs.202672
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s4216
          Validated

          Purification
          Size
          Availability Inventoried
          Catalog # 4390824
          Price 7,898.00
          Your Price
          Online offer:
          7898.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: DNMT1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001130823.2 NP_001124295.1 25 2539
          NM_001318730.1 NP_001305659.1 24 2410
          NM_001318731.1 NP_001305660.1 25 2418
          NM_001379.3 NP_001370.1 24 2491
          GenBank mRNA AB209413.2 - 24 2217
          AF180682.1 - 22 1998
          BC092517.1 - 25 2298 3077831
          BC126227.1 - 25 2483 8991943
          BC144093.1 - 25 2483 9052613
          X63692.1 - 24 2492

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          More Information


          Matching Taqman Gene Expression Assay:


          Hs00154749_m1

          Panther Classification:

          Molecular Function -

          DNA metabolism protein DNA methyltransferase nucleic acid metabolism protein

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          DNA methylation
          transcription, DNA-templated
          Ras protein signal transduction
          brain development
          aging
          response to heat
          response to toxic substance
          response to ionizing radiation
          maintenance of DNA methylation
          DNA methylation on cytosine within a CG sequence
          positive regulation of gene expression
          response to activity
          gene silencing
          covalent chromatin modification
          neuron differentiation
          response to caffeine
          response to estradiol
          response to lipopolysaccharide
          response to vitamin A
          response to testosterone
          cellular response to platelet-derived growth factor stimulus
          response to antidepressant
          regulation of cell proliferation
          DNA hypermethylation
          response to ethanol
          negative regulation of gene expression, epigenetic
          S-adenosylhomocysteine metabolic process
          S-adenosylmethioninamine metabolic process
          S-adenosylmethionine metabolic process
          positive regulation of histone H3-K4 methylation
          negative regulation of histone H3-K9 methylation
          cellular response to amino acid stimulus
          cellular response to lead ion
          cellular response to transforming growth factor beta stimulus
          C-5 methylation of cytosine
          positive regulation of methylation-dependent chromatin silencing
          cellular response to nerve growth factor stimulus
          DNA binding
          double-stranded DNA binding
          RNA binding
          DNA (cytosine-5-)-methyltransferase activity
          protein binding
          zinc ion binding
          methyl-CpG binding
          DNA-methyltransferase activity
          protein domain specific binding
          estrogen receptor binding
          histone deacetylase binding
          unmethylated CpG binding
          DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
          promoter-specific chromatin binding

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