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          System Message

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          LOADING ...
          See other HFE SIRNA Assays ›
          Gene Symbol:
          HFE
          Gene Name:
          hemochromatosis
          Gene Aliases:
          HFE1, HH, HLA-H, MVCD7, TFQTL2
          Chromosome Location:
          Chr.6: 26087281 - 26096216 on Build GRCh38
          UniGene ID:
          Hs.233325
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s502535

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 388.00
          Your Price
          Online offer: 374.65
          374.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: HFE
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000410.3 NP_000401.1 6 2086
          NM_001300749.1 NP_001287678.1 6 1868
          NM_139003.2 NP_620572.1 5 1768
          NM_139004.2 NP_620573.1 5 1810
          NM_139006.2 NP_620575.1 6 2044
          NM_139007.2 NP_620576.1 5 1822
          NM_139008.2 NP_620577.1 5 1780
          NM_139009.2 NP_620578.1 6 2017
          NM_139010.2 NP_620579.1 4 1546
          NM_139011.2 NP_620580.1 3 1270
          XM_011514543.2 XP_011512845.1 7 1863
          GenBank mRNA AF144242.1 - 5 1773
          AJ298839.1 - 1 138
          AJ298840.1 - 1 138
          AJ404378.1 - 1 32
          U60319.1 - 6 2147

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          More Information


          Panther Classification:

          Molecular Function -

          major histocompatibility complex protein

          Gene Ontology Categories:

          Function(s) Process(es)

          antigen processing and presentation of peptide antigen via MHC class I
          negative regulation of T cell antigen processing and presentation
          negative regulation of T cell cytokine production
          protein complex assembly
          cellular iron ion homeostasis
          acute-phase response
          immune response
          female pregnancy
          response to iron ion
          cellular response to iron ion starvation
          positive regulation of gene expression
          positive regulation of pathway-restricted SMAD protein phosphorylation
          antigen processing and presentation
          BMP signaling pathway
          positive regulation of protein binding
          negative regulation of proteasomal ubiquitin-dependent protein catabolic process
          hormone biosynthetic process
          positive regulation of receptor-mediated endocytosis
          iron ion homeostasis
          multicellular organismal iron ion homeostasis
          cellular response to iron ion
          positive regulation of peptide hormone secretion
          liver regeneration
          iron ion import into cell
          negative regulation of receptor binding
          positive regulation of receptor binding
          positive regulation of ferrous iron import into cell
          negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
          positive regulation of ferrous iron binding
          positive regulation of transferrin receptor binding
          response to iron ion starvation
          regulation of protein localization to cell surface
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          negative regulation of receptor activity
          positive regulation of receptor activity
          negative regulation of CD8-positive, alpha-beta T cell activation
          antigen binding
          receptor binding
          protein binding
          beta-2-microglobulin binding
          co-receptor binding
          peptide antigen binding
          transferrin receptor binding

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