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          System Message

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          LOADING ...
          See other FMR1 SIRNA Assays ›
          Gene Symbol:
          FMR1
          Gene Name:
          fragile X mental retardation 1
          Gene Aliases:
          FMRP, FRAXA, POF, POF1
          Chromosome Location:
          Chr.X: 147911951 - 147951127 on Build GRCh38
          UniGene ID:
          Hs.103183
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s5317

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: FMR1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001185076.1 NP_001172005.1 13 1560
          NM_001185082.1 NP_001172011.1 13 1560
          NM_002024.5 NP_002015.1 14 1623
          GenBank mRNA AB209188.1 - 9 2050
          AK294104.1 - 3 343
          AK302707.1 - 8 884
          BC086957.1 - 13 1590 30347992
          CN315330.1 - 4 434
          CX871385.1 - 2 198
          KC774027.1 - 13 1393
          KC774029.1 - 12 1258
          KF856234.1 - 12 1258
          KJ534836.1 - 13 1331
          KJ534837.1 - 14 1394
          KJ534838.1 - 13 1331
          KM091457.1 - 15 1502
          KM091458.1 - 14 1439
          KM091459.1 - 15 1502
          M67468.1 - 13 1520
          S65791.1 - 14 1613
          X69962.1 - 14 1613

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_052804, XM_006229530, XM_006229531, XM_006229535, XM_008773597, and others.
          This siRNA also targets the following transcripts in Mouse: NM_001290424, NM_008031, L23971, BC079671, AF461114.

          Panther Classification:

          Molecular Function -

          translation factor

          Gene Ontology Categories:

          Function(s) Process(es)

          regulation of alternative mRNA splicing, via spliceosome
          positive regulation of receptor internalization
          mRNA processing
          cellular response to DNA damage stimulus
          glutamate receptor signaling pathway
          RNA splicing
          negative regulation of translation
          gene silencing by RNA
          positive regulation of histone phosphorylation
          cellular response to UV
          regulation of mRNA stability
          modulation by host of viral RNA genome replication
          positive regulation of translation
          negative regulation of translational initiation
          regulation of neurotransmitter secretion
          mRNA transport
          regulation of filopodium assembly
          positive regulation of filopodium assembly
          regulation of gene silencing by miRNA
          regulation of dendritic spine development
          positive regulation of dendritic spine development
          cellular response to hydroxyurea
          cellular response to virus
          regulation of neuronal action potential
          negative regulation of long term synaptic depression
          positive regulation of intracellular transport of viral material
          negative regulation of voltage-gated calcium channel activity
          positive regulation of proteasomal protein catabolic process
          positive regulation of mRNA binding
          negative regulation of synaptic vesicle exocytosis
          positive regulation of gene silencing by miRNA
          negative regulation of cytoplasmic translation
          positive regulation of response to DNA damage stimulus
          G-quadruplex RNA binding
          chromatin binding
          RNA binding
          mRNA binding
          mRNA 3'-UTR binding
          protein binding
          microtubule binding
          poly(U) RNA binding
          translation repressor activity
          translation initiation factor binding
          RNA strand annealing activity
          poly(G) binding
          methylated histone binding
          siRNA binding
          miRNA binding
          RNA stem-loop binding
          identical protein binding
          protein homodimerization activity
          ribosome binding
          ion channel binding
          poly(A) RNA binding
          dynein binding
          protein heterodimerization activity
          mRNA 5'-UTR binding
          sequence-specific mRNA binding

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          Host server : magellan-search-green-55658555d6-9gcvf:80/100.66.77.125:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline