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          LOADING ...
          See other CHEK2 SIRNA Assays ›
          Gene Symbol:
          CHEK2
          Gene Name:
          checkpoint kinase 2
          Gene Aliases:
          CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
          Chromosome Location:
          Chr.22: 28687743 - 28741866 on Build GRCh38
          UniGene ID:
          Hs.291363
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s533978

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 388.00
          Your Price
          Online offer: 374.65
          374.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CHEK2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001005735.1 NP_001005735.1 5 671
          NM_001257387.1 NP_001244316.1 4 542
          NM_007194.3 NP_009125.1 4 542
          NM_145862.2 NP_665861.1 4 542
          XM_011529839.2 XP_011528141.1 5 693
          XM_011529840.2 XP_011528142.1 5 695
          XM_011529844.2 XP_011528146.1 5 703
          XM_011529845.2 XP_011528147.1 3 249
          XM_017028560.1 XP_016884049.1 5 657
          GenBank mRNA AB040105.1 - 3 470
          AF086904.1 - 3 470
          AF096279.1 - 3 470
          AF174135.1 - 3 470
          AF217975.1 - 4 1141
          AJ131197.1 - 3 470
          AJ783839.1 - 3 470
          AK289360.1 - 4 521
          AK290754.1 - 4 544
          AY551297.1 - 4 599
          AY551298.1 - 3 470
          AY551299.1 - 3 470
          AY551300.1 - 3 470
          AY551302.1 - 3 470
          AY551305.1 - 3 470
          BC004207.2 - 4 497 3532866
          CR456418.1 - 5 670

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          DNA damage checkpoint
          G2/M transition of mitotic cell cycle
          replicative cell aging
          positive regulation of protein phosphorylation
          double-strand break repair
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          protein phosphorylation
          cellular response to DNA damage stimulus
          DNA damage induced protein phosphorylation
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          intrinsic apoptotic signaling pathway in response to DNA damage
          response to gamma radiation
          peptidyl-serine phosphorylation
          cellular response to drug
          regulation of protein catabolic process
          signal transduction in response to DNA damage
          cellular protein catabolic process
          positive regulation of transcription, DNA-templated
          protein autophosphorylation
          protein stabilization
          cell division
          negative regulation of cell cycle arrest
          signal transduction involved in intra-S DNA damage checkpoint
          mitotic spindle assembly
          replicative senescence
          regulation of signal transduction by p53 class mediator
          response to doxorubicin
          cellular response to bisphenol A
          negative regulation of DNA damage checkpoint
          positive regulation of anoikis
          protein serine/threonine kinase activity
          protein binding
          ATP binding
          protein kinase binding
          ubiquitin protein ligase binding
          identical protein binding
          protein homodimerization activity
          metal ion binding

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