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          System Message

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          LOADING ...
          See other NLRP3 SIRNA Assays ›
          Gene Symbol:
          NLRP3
          Gene Name:
          NLR family pyrin domain containing 3
          Gene Aliases:
          AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCAS1, FCU, MWS, NALP3, PYPAF1
          Chromosome Location:
          Chr.1: 247416156 - 247449108 on Build GRCh38
          UniGene ID:
          Hs.159483
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s534396

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: NLRP3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001079821.2 NP_001073289.1 4 521
          NM_001127461.2 NP_001120933.1 3 1163
          NM_001127462.2 NP_001120934.1 2 1129
          NM_001243133.1 NP_001230062.1 2 1129
          NM_004895.4 NP_004886.3 2 1129
          NM_183395.2 NP_899632.1 2 1129
          XM_011544048.2 XP_011542350.1 3 1268
          XM_011544053.2 XP_011542355.1 3 1156
          XM_011544055.2 XP_011542357.1 3 1156
          XM_017000181.1 XP_016855670.1 4 745
          XM_017000182.1 XP_016855671.1 4 690
          XM_017000183.1 XP_016855672.1 3 1156
          XM_017000184.1 XP_016855673.1 3 1156
          GenBank mRNA AB208891.1 - 2 1138
          AF410477.1 - 2 1129
          AF418985.2 - 2 545
          AF420469.1 - 3 515
          AF427617.1 - 2 1129
          AF468522.1 - 2 545
          AK027194.1 - 2 558
          AK314998.1 - 4 521
          AY092033.1 - 2 545
          AY422168.1 - 2 377
          BC117211.1 - 2 448 40125762
          BC143359.1 - 2 448 9051864
          BC143362.1 - 2 448 9051867
          BC143363.1 - 2 448 9051868
          DA244290.1 - 4 521

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          More Information


          Panther Classification:

          Molecular Function -

          non-motor microtubule binding protein

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of acute inflammatory response
          positive regulation of type 2 immune response
          transcription, DNA-templated
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          defense response
          inflammatory response
          signal transduction
          detection of biotic stimulus
          negative regulation of NF-kappaB transcription factor activity
          interleukin-1 beta production
          interleukin-18 production
          positive regulation of interleukin-13 production
          positive regulation of interleukin-4 production
          positive regulation of interleukin-5 production
          negative regulation of NF-kappaB import into nucleus
          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
          NLRP3 inflammasome complex assembly
          innate immune response
          positive regulation of T-helper 2 cell differentiation
          positive regulation of transcription from RNA polymerase II promoter
          interleukin-1 secretion
          negative regulation of interleukin-1 beta secretion
          positive regulation of interleukin-1 beta secretion
          negative regulation of inflammatory response
          positive regulation of NF-kappaB transcription factor activity
          protein oligomerization
          defense response to virus
          cellular response to lipopolysaccharide
          positive regulation of T-helper 17 cell differentiation
          positive regulation of T-helper 2 cell cytokine production
          protein binding
          ATP binding
          transcription factor binding
          peptidoglycan binding
          sequence-specific DNA binding

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