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          System Message

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          LOADING ...
          See other ATM SIRNA Assays ›
          Gene Symbol:
          ATM
          Gene Name:
          ATM serine/threonine kinase
          Gene Aliases:
          AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
          Chromosome Location:
          Chr.11: 108222484 - 108369102 on Build GRCh38
          UniGene ID:
          Hs.367437
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s536307

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ATM
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000051.3 NP_000042.3 29 4775
          XM_005271561.4 XP_005271618.2 30 4836
          XM_005271562.4 XP_005271619.2 29 4909
          XM_006718843.3 XP_006718906.1 29 4542
          XM_006718845.1 XP_006718908.1 4 415
          XM_011542840.2 XP_011541142.1 30 4630
          XM_011542842.2 XP_011541144.1 28 4584
          XM_011542843.2 XP_011541145.1 29 5123
          XM_011542844.2 XP_011541146.1 29 4725
          XM_011542845.1 XP_011541147.1 21 3238
          XM_017017789.1 XP_016873278.1 30 5333
          XM_017017790.1 XP_016873279.1 29 4730
          XM_017017791.1 XP_016873280.1 29 5123
          XM_017017792.1 XP_016873281.1 29 5123
          GenBank mRNA BC007023.2 - 3 399
          BC137169.1 - 3 413 9021166
          BC152385.1 - 3 349
          BC152389.1 - 3 349
          BT006764.1 - 3 346
          U26455.1 - 3 605
          U33841.1 - 30 4579

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          double-strand break repair via homologous recombination
          DNA double-strand break processing
          DNA synthesis involved in DNA repair
          strand displacement
          response to hypoxia
          somitogenesis
          pre-B cell allelic exclusion
          DNA replication
          DNA repair
          double-strand break repair via nonhomologous end joining
          protein phosphorylation
          cellular response to DNA damage stimulus
          DNA damage induced protein phosphorylation
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          telomere maintenance via telomerase
          cell cycle arrest
          mitotic spindle assembly checkpoint
          reciprocal meiotic recombination
          signal transduction
          brain development
          heart development
          determination of adult lifespan
          intrinsic apoptotic signaling pathway in response to DNA damage
          response to ionizing radiation
          regulation of autophagy
          histone phosphorylation
          peptidyl-serine phosphorylation
          negative regulation of B cell proliferation
          positive regulation of telomere maintenance via telomerase
          positive regulation of histone phosphorylation
          V(D)J recombination
          phosphatidylinositol-3-phosphate biosynthetic process
          peptidyl-serine autophosphorylation
          lipoprotein catabolic process
          regulation of apoptotic process
          positive regulation of apoptotic process
          positive regulation of DNA damage response, signal transduction by p53 class mediator
          positive regulation of neuron apoptotic process
          meiotic telomere clustering
          protein autophosphorylation
          oocyte development
          neuron apoptotic process
          regulation of telomerase activity
          histone mRNA catabolic process
          cellular response to gamma radiation
          cellular response to X-ray
          cellular response to nitrosative stress
          signal transduction involved in mitotic G2 DNA damage checkpoint
          replicative senescence
          establishment of RNA localization to telomere
          establishment of macromolecular complex localization to telomere
          regulation of cellular response to heat
          regulation of signal transduction by p53 class mediator
          negative regulation of TORC1 signaling
          negative regulation of telomere capping
          positive regulation of telomere maintenance via telomere lengthening
          positive regulation of telomerase catalytic core complex assembly
          DNA binding
          protein serine/threonine kinase activity
          DNA-dependent protein kinase activity
          protein binding
          ATP binding
          1-phosphatidylinositol-3-kinase activity
          protein complex binding
          protein dimerization activity
          protein N-terminus binding

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