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          System Message

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          LOADING ...
          See other TP53 SIRNA Assays ›
          Gene Symbol:
          TP53
          Gene Name:
          tumor protein p53
          Gene Aliases:
          BCC7, LFS1, P53, TRP53
          Chromosome Location:
          Chr.17: 7668402 - 7687550 on Build GRCh38
          UniGene ID:
          Hs.437460
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s536423

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: TP53
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000546.5 NP_000537.3 8 1055
          NM_001126112.2 NP_001119584.1 8 1052
          NM_001126113.2 NP_001119585.1 8 1055
          NM_001126114.2 NP_001119586.1 8 1055
          NM_001126115.1 NP_001119587.1 4 735
          NM_001126116.1 NP_001119588.1 4 735
          NM_001126117.1 NP_001119589.1 4 735
          NM_001126118.1 NP_001119590.1 7 1172
          NM_001276695.1 NP_001263624.1 8 1055
          NM_001276696.1 NP_001263625.1 8 1055
          NM_001276697.1 NP_001263626.1 4 735
          NM_001276698.1 NP_001263627.1 4 735
          NM_001276699.1 NP_001263628.1 4 735
          NM_001276760.1 NP_001263689.1 8 1055
          NM_001276761.1 NP_001263690.1 8 1052
          GenBank mRNA AB082923.1 - 8 916
          AF307851.1 - 8 988
          AK223026.1 - 2 148
          AK225838.1 - 8 993
          AK297462.1 - 9 920
          AK297927.1 - 9 965
          AK312568.1 - 8 997
          AM076970.1 - 7 820
          AM076972.1 - 7 853
          AY429684.1 - 7 853
          BC003596.1 - 8 973 3544714
          BT019622.1 - 7 853
          DQ186648.1 - 8 985
          DQ186649.1 - 8 985
          DQ186650.1 - 4 731
          DQ186651.1 - 4 731
          DQ186652.1 - 4 731
          DQ191317.1 - 8 1042
          DQ263704.1 - 7 853
          DQ286964.1 - 8 987
          EF101867.1 - 7 820
          EF101868.1 - 7 853
          FJ207420.1 - 8 988
          JN214348.1 - 7 898
          JN601513.1 - 7 853
          JN601514.1 - 7 853
          JN601516.1 - 8 827
          JN900492.1 - 7 1161
          JQ026207.1 - 7 843
          JQ026208.1 - 7 848
          JQ026209.1 - 7 858
          JQ026210.1 - 7 848
          JQ694049.1 - 7 876
          JQ694050.1 - 7 876
          JQ694051.1 - 7 876
          M14694.1 - 8 978
          M14695.1 - 8 974
          X01405.1 - 5 554
          X02469.1 - 8 988
          X60011.1 - 7 853
          X60012.1 - 7 853
          X60013.1 - 7 853
          X60014.1 - 7 853
          X60015.1 - 7 853
          X60016.1 - 7 853
          X60017.1 - 7 853
          X60018.1 - 7 853
          X60019.1 - 7 853
          X60020.1 - 7 853

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: XM_003749209.

          Panther Classification:

          Molecular Function -

          P53-like transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          DNA strand renaturation
          base-excision repair
          nucleotide-excision repair
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          protein complex assembly
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          ER overload response
          cell cycle arrest
          Ras protein signal transduction
          multicellular organism development
          cell aging
          protein localization
          cell proliferation
          negative regulation of cell proliferation
          determination of adult lifespan
          response to X-ray
          response to gamma radiation
          positive regulation of gene expression
          viral process
          protein sumoylation
          cell differentiation
          negative regulation of cell growth
          DNA damage response, signal transduction by p53 class mediator
          positive regulation of histone deacetylation
          chromatin assembly
          mitotic G1 DNA damage checkpoint
          positive regulation of protein oligomerization
          cellular response to UV
          cellular response to drug
          cellular response to glucose starvation
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          entrainment of circadian clock by photoperiod
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of neuron apoptotic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          response to antibiotic
          positive regulation of protein export from nucleus
          regulation of mitochondrial membrane permeability
          negative regulation of fibroblast proliferation
          circadian behavior
          positive regulation of peptidyl-tyrosine phosphorylation
          negative regulation of helicase activity
          protein tetramerization
          negative regulation of telomerase activity
          positive regulation of thymocyte apoptotic process
          positive regulation of cell cycle arrest
          cellular response to hypoxia
          cellular response to ionizing radiation
          intrinsic apoptotic signaling pathway by p53 class mediator
          positive regulation of release of cytochrome c from mitochondria
          replicative senescence
          oxidative stress-induced premature senescence
          intrinsic apoptotic signaling pathway
          oligodendrocyte apoptotic process
          positive regulation of execution phase of apoptosis
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of signal transduction by p53 class mediator
          regulation of cell cycle G2/M phase transition
          positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
          positive regulation of reactive oxygen species metabolic process
          positive regulation of intrinsic apoptotic signaling pathway
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          protease binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          copper ion binding
          protein binding
          ATP binding
          transcription factor binding
          zinc ion binding
          enzyme binding
          protein kinase binding
          protein phosphatase binding
          receptor tyrosine kinase binding
          ubiquitin protein ligase binding
          histone acetyltransferase binding
          identical protein binding
          sequence-specific DNA binding
          protein self-association
          transcription regulatory region DNA binding
          protein heterodimerization activity
          protein N-terminus binding
          chaperone binding
          protein phosphatase 2A binding

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          Host server : magellan-search-green-55658555d6-qfdf2:80/100.66.76.55:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline