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          System Message

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          LOADING ...
          See other IL12B SIRNA Assays ›
          Gene Symbol:
          IL12B
          Gene Name:
          interleukin 12B
          Gene Aliases:
          CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2
          Chromosome Location:
          Chr.5: 159314783 - 159330473 on Build GRCh38
          UniGene ID:
          Hs.674
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s7359

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: IL12B
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002187.2 NP_002178.2 3 394
          GenBank mRNA AF180563.1 - 2 358
          BC067498.1 - 2 356 6971868
          BC067499.1 - 2 356 6971869
          BC067500.1 - 2 356 6971872
          BC067501.1 - 2 356 6971873
          BC067502.1 - 2 356 6971874
          BC074723.2 - 3 383 30915173
          M65272.1 - 3 394
          M65290.1 - 2 365

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          More Information


          Panther Classification:

          Molecular Function -

          transmembrane signal receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          positive regulation of T cell mediated cytotoxicity
          positive regulation of defense response to virus by host
          natural killer cell activation involved in immune response
          positive regulation of T-helper 1 type immune response
          positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
          negative regulation of inflammatory response to antigenic stimulus
          cell cycle arrest
          response to UV-B
          positive regulation of activation of JAK2 kinase activity
          cell migration
          cytokine-mediated signaling pathway
          sensory perception of pain
          sexual reproduction
          natural killer cell activation
          negative regulation of interleukin-10 production
          negative regulation of interleukin-17 production
          positive regulation of granulocyte macrophage colony-stimulating factor production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-17 production
          positive regulation of tumor necrosis factor production
          positive regulation of natural killer cell activation
          positive regulation of natural killer cell proliferation
          positive regulation of mononuclear cell proliferation
          positive regulation of tissue remodeling
          positive regulation of smooth muscle cell apoptotic process
          regulation of cytokine biosynthetic process
          T-helper 1 type immune response
          T-helper cell differentiation
          interferon-gamma biosynthetic process
          positive regulation of T cell proliferation
          positive regulation of activated T cell proliferation
          positive regulation of NF-kappaB import into nucleus
          regulation of tyrosine phosphorylation of Stat1 protein
          positive regulation of tyrosine phosphorylation of Stat3 protein
          positive regulation of tyrosine phosphorylation of Stat4 protein
          positive regulation of tyrosine phosphorylation of Stat5 protein
          defense response to protozoan
          positive regulation of memory T cell differentiation
          negative regulation of growth of symbiont in host
          positive regulation of interferon-gamma biosynthetic process
          positive regulation of osteoclast differentiation
          positive regulation of cell adhesion
          negative regulation of smooth muscle cell proliferation
          positive regulation of lymphocyte proliferation
          positive regulation of inflammatory response
          defense response to Gram-negative bacterium
          positive regulation of NK T cell activation
          positive regulation of NK T cell proliferation
          defense response to virus
          cellular response to lipopolysaccharide
          cellular response to interferon-gamma
          positive regulation of T-helper 17 type immune response
          positive regulation of T-helper 17 cell lineage commitment
          cytokine receptor activity
          cytokine activity
          interleukin-12 receptor binding
          protein binding
          growth factor activity
          interleukin-12 alpha subunit binding
          identical protein binding
          protein homodimerization activity
          interleukin-23 receptor binding
          protein heterodimerization activity

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