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          System Message

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          LOADING ...
          See other SNCA SIRNA Assays ›
          Gene Symbol:
          Snca
          Gene Name:
          synuclein, alpha
          Gene Aliases:
          NACP, alphaSYN
          Chromosome Location:
          Chr.6: 60731573 - 60829855 on Build GRCm38
          UniGene ID:
          Mm.17484
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID s74073

          Purification
          Size
          Availability Made To Order
          Catalog # 4390771
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Snca
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001042451.2 NP_001035916.1 4 491
          NM_009221.2 NP_033247.1 4 395
          GenBank mRNA AF033261.1 - 4 318
          AF044672.1 - 3 223
          AF179273.1 - 4 395
          AK014472.1 - 4 360
          AK156316.1 - 4 327
          AK205246.1 - 3 217
          BC046764.1 - 4 234 5693785

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_001146054, NM_007308, NM_000345, NM_001146055, HQ830267, and others.
          This siRNA also targets the following transcripts in Rat: S73008, AY550006, AF007758, S73007, AY550005.

          Panther Classification:

          Molecular Function -

          membrane trafficking regulatory protein

          Gene Ontology Categories:

          Function(s) Process(es)

          microglial cell activation
          positive regulation of receptor recycling
          negative regulation of protein phosphorylation
          positive regulation of neurotransmitter secretion
          synaptic transmission, dopaminergic
          fatty acid metabolic process
          neutral lipid metabolic process
          phospholipid metabolic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          mitochondrial membrane organization
          chemical synaptic transmission
          adult locomotory behavior
          response to iron(II) ion
          regulation of phospholipase activity
          negative regulation of platelet-derived growth factor receptor signaling pathway
          regulation of glutamate secretion
          regulation of dopamine secretion
          negative regulation of microtubule polymerization
          receptor internalization
          protein destabilization
          response to magnesium ion
          negative regulation of transporter activity
          response to lipopolysaccharide
          negative regulation of monooxygenase activity
          positive regulation of peptidyl-serine phosphorylation
          response to interferon-gamma
          cellular response to oxidative stress
          negative regulation of histone acetylation
          regulation of locomotion
          dopamine biosynthetic process
          dopamine metabolic process
          response to drug
          mitochondrial ATP synthesis coupled electron transport
          regulation of macrophage activation
          negative regulation of apoptotic process
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          regulation of neuron apoptotic process
          negative regulation of neuron apoptotic process
          positive regulation of endocytosis
          negative regulation of exocytosis
          negative regulation of dopamine metabolic process
          regulation of neurotransmitter secretion
          behavioral response to cocaine
          regulation of neuronal synaptic plasticity
          regulation of long-term neuronal synaptic plasticity
          synaptic vesicle endocytosis
          synaptic vesicle transport
          positive regulation of synaptic transmission
          synapse organization
          regulation of acyl-CoA biosynthetic process
          positive regulation of release of sequestered calcium ion into cytosol
          negative regulation of dopamine uptake involved in synaptic transmission
          negative regulation of serotonin uptake
          negative regulation of norepinephrine uptake
          oxidation-reduction process
          excitatory postsynaptic potential
          long-term synaptic potentiation
          positive regulation of inositol phosphate biosynthetic process
          membrane organization
          negative regulation of thrombin receptor signaling pathway
          response to interleukin-1
          cellular response to copper ion
          positive regulation of protein serine/threonine kinase activity
          regulation of neuron death
          positive regulation of glutathione peroxidase activity
          positive regulation of hydrogen peroxide catabolic process
          regulation of reactive oxygen species metabolic process
          magnesium ion binding
          copper ion binding
          calcium ion binding
          protein binding
          phospholipid binding
          microtubule binding
          ferrous iron binding
          zinc ion binding
          oxidoreductase activity
          kinesin binding
          enzyme binding
          protein domain specific binding
          Hsp70 protein binding
          histone binding
          identical protein binding
          alpha-tubulin binding
          cysteine-type endopeptidase inhibitor activity involved in apoptotic process
          phospholipase binding
          dynein binding
          metal ion binding
          protein N-terminus binding
          tau protein binding
          beta-tubulin binding
          arachidonic acid binding
          phosphoprotein binding

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