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          System Message

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          LOADING ...
          See other SMAD7 SIRNA Assays ›
          Gene Symbol:
          SMAD7
          Gene Name:
          SMAD family member 7
          Gene Aliases:
          CRCS3, MADH7, MADH8
          Chromosome Location:
          Chr.18: 48919853 - 48950711 on Build GRCh38
          UniGene ID:
          Hs.465087
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s8413

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: SMAD7
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001190821.1 NP_001177750.1 4 1144
          NM_001190822.1 NP_001177751.1 4 352
          NM_001190823.1 NP_001177752.1 2 445
          NM_005904.3 NP_005895.1 4 1147
          GenBank mRNA AF010193.1 - 4 1155
          AF015261.1 - 4 860
          AK131394.1 - 2 387
          AK301535.1 - 4 352
          BC074818.2 - 4 894 30915321
          BC074819.2 - 4 894 30915535
          BP363832.1 - 2 445

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_030858, XM_006254959, AF159626, AF042499.
          This siRNA also targets the following transcripts in Mouse: NM_001042660, BC137638, AJ000550, AF015260, AJ000551, and others.

          Panther Classification:

          Molecular Function -

          DNA-binding transcription factor gene-specific transcriptional regulator

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          ureteric bud development
          transcription, DNA-templated
          transforming growth factor beta receptor signaling pathway
          regulation of epithelial to mesenchymal transition
          negative regulation of epithelial to mesenchymal transition
          negative regulation of peptidyl-threonine phosphorylation
          negative regulation of transcription by competitive promoter binding
          regulation of transforming growth factor beta receptor signaling pathway
          positive regulation of cell-cell adhesion
          negative regulation of cell migration
          BMP signaling pathway
          negative regulation of transforming growth factor beta receptor signaling pathway
          negative regulation of BMP signaling pathway
          negative regulation of protein ubiquitination
          positive regulation of protein ubiquitination
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          regulation of activin receptor signaling pathway
          negative regulation of peptidyl-serine phosphorylation
          adherens junction assembly
          response to laminar fluid shear stress
          cellular protein complex localization
          intracellular signal transduction
          negative regulation of sequence-specific DNA binding transcription factor activity
          positive regulation of transcription from RNA polymerase II promoter
          artery morphogenesis
          protein stabilization
          negative regulation of ubiquitin-protein transferase activity
          ventricular cardiac muscle tissue morphogenesis
          regulation of cardiac muscle contraction
          regulation of ventricular cardiac muscle cell membrane depolarization
          pathway-restricted SMAD protein phosphorylation
          negative regulation of pathway-restricted SMAD protein phosphorylation
          ventricular septum morphogenesis
          cellular response to transforming growth factor beta stimulus
          transcription factor activity, sequence-specific DNA binding
          protein binding
          collagen binding
          beta-catenin binding
          transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
          ubiquitin protein ligase binding
          type I transforming growth factor beta receptor binding
          transcription regulatory region DNA binding
          metal ion binding
          activin binding
          I-SMAD binding

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