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          System Message

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          LOADING ...
          See other DAB2IP SIRNA Assays ›
          Gene Symbol:
          Dab2ip
          Gene Name:
          disabled 2 interacting protein
          Gene Aliases:
          2310011D08Rik, AI480459, Aip1, mKIAA1743
          Chromosome Location:
          Chr.2: 35558458 - 35730994 on Build GRCm38
          UniGene ID:
          Mm.29629
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID s88000

          Purification
          Size
          Availability Made To Order
          Catalog # 4390771
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Dab2ip
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001001602.2 NP_001001602.2 5, 6 1372
          NM_001114124.2 NP_001107596.1 7, 8 1496
          NM_001114125.1 NP_001107597.1 7, 8 1348
          NM_001290637.1 NP_001277566.1 7, 8 1403
          NM_001290639.1 NP_001277568.1 5, 6 1031
          NM_001290640.1 NP_001277569.1 5, 6 1336
          NM_001290641.1 NP_001277570.1 7, 8 1629
          GenBank mRNA AK122548.1 - 2, 3 336
          AK147464.1 - 7, 8 1428
          AK147593.1 - 7, 8 1630
          AK155296.1 - 7, 8 1404
          AY305656.1 - 5, 6 1089
          AY305657.1 - 5, 6 1372
          AY305658.1 - 5, 6 1031
          BC094373.1 - 2, 3 193
          BC118530.1 - 5, 6 997 40098202
          DQ473307.1 - 7, 8 1233

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_138710, XM_006234057, XM_008761697, XM_008761699, XM_008761698, and others.

          Panther Classification:

          Molecular Function -

          GTPase-activating protein

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          activation of MAPKKK activity
          angiogenesis
          negative regulation of protein phosphorylation
          immune system process
          apoptotic process
          inflammatory response
          response to unfolded protein
          cell cycle
          signal transduction
          I-kappaB phosphorylation
          activation of JUN kinase activity
          multicellular organism development
          negative regulation of cell proliferation
          extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of endothelial cell migration
          negative regulation of epithelial cell migration
          negative regulation of epithelial to mesenchymal transition
          positive regulation of neuron projection development
          negative regulation of phosphatidylinositol 3-kinase signaling
          negative regulation of angiogenesis
          cell motility involved in cerebral cortex radial glia guided migration
          layer formation in cerebral cortex
          negative regulation of cell growth
          negative regulation of vascular endothelial growth factor receptor signaling pathway
          negative regulation of NF-kappaB transcription factor activity
          negative regulation of toll-like receptor 4 signaling pathway
          negative regulation of GTPase activity
          tube formation
          negative regulation of catenin import into nucleus
          cellular response to vascular endothelial growth factor stimulus
          vascular endothelial growth factor receptor-2 signaling pathway
          reelin-mediated signaling pathway
          regulation of growth
          negative regulation of epidermal growth factor receptor signaling pathway
          positive regulation of apoptotic process
          regulation of GTPase activity
          regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          regulation of protein complex assembly
          negative regulation of MAP kinase activity
          positive regulation of MAPK cascade
          regulation of protein heterodimerization activity
          positive regulation of JUN kinase activity
          positive regulation of GTPase activity
          negative regulation of phosphatidylinositol 3-kinase activity
          cellular protein catabolic process
          innate immune response
          positive regulation of protein catabolic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          negative regulation of Ras protein signal transduction
          negative regulation of fibroblast proliferation
          neuron projection morphogenesis
          negative regulation of epithelial cell proliferation
          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
          negative regulation of G0 to G1 transition
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of cell cycle arrest
          cellular response to lipopolysaccharide
          cellular response to interleukin-1
          cellular response to tumor necrosis factor
          cellular response to epidermal growth factor stimulus
          negative regulation of protein serine/threonine kinase activity
          positive regulation of protein serine/threonine kinase activity
          negative regulation of canonical Wnt signaling pathway
          positive regulation of synapse maturation
          positive regulation of dendrite development
          regulation of p38MAPK cascade
          negative regulation of vascular endothelial growth factor signaling pathway
          positive regulation of proteasomal protein catabolic process
          negative regulation of cyclin catabolic process
          positive regulation of neuron migration
          positive regulation of apoptotic signaling pathway
          GTPase activator activity
          death receptor binding
          protein binding
          SH3 domain binding
          kinase binding
          protein kinase binding
          mitogen-activated protein kinase kinase binding
          mitogen-activated protein kinase kinase kinase binding
          phosphatidylinositol-3-phosphate binding
          protein complex binding
          signaling adaptor activity
          Toll-like receptor 4 binding
          phosphatidylinositol 3-kinase regulatory subunit binding
          identical protein binding
          protein homodimerization activity
          vascular endothelial growth factor receptor 2 binding
          phosphatidylinositol 3-kinase binding
          protein N-terminus binding
          protein phosphatase 2A binding
          phosphatidylinositol-4-phosphate binding
          14-3-3 protein binding

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