1 hr 20 min
4 hr 45 min
Homogenous (no wash)
Colorimetric Microplate Reader
Pre-coated 96 well plate
Assay Diluent concentrate
Biotinylated Detection Antibody
Adhesive Plate Covers
Wet or Dry Ice
CD321, JAM-1, JAM-A, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM-1, Platelet adhesion molecule 1, Platelet F11 receptor
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Label or dye
CD321, F11R, JAM, JAM1, JAMA, JCAM, KAT, PAM-1, UNQ264/PRO301
Human JAM-A/CD321/F11R quantitates human JAM-A/CD321/F11R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human JAM-A/CD321/F11R.
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.