CD32, CDw32, Fc fragment of IgG, low affinity II, receptor for (CD32), low affinity IIa, receptor (CD32), low affinity IIb, low affinity IIc, Fc gamma receptor IIa, Fc gamma receptor IIb, Fc gamma receptor IIC, Fc gamma RIIb, Fc-gamma RII-a, Fc-gamma RII-b, Fc-gamma RII-c, Fc-gamma-RIIa, Fc-gamma-RIIb, Fc-gamma-RIIc, fcRII-a, fcRII-b, IgG Fc receptor II-a, IgG Fc receptor II-b, IgG Fc receptor II-c, Immunoglobulin G Fc receptor II, immunoglobulin G Fc receptor II-c, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c
The Human FcGR2BC (CD32 B/C) ELISA quantitates Hu FcGR2BC in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu FcGR2BC.
Principle of the method
The Human FcGR2BC solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.