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f290 Oyster

Whole Allergen
Code f290
LOINC 7558-0
Family Ostreidae
Source Material Fresh whole oyster
Latin Name Ostrea edulis
Other Names Oyster
Categories Food Of Animal Origin, Mollusks

Route of Exposure Section



Other topics

Undeclared oyster sauce in various dishes

Clinical Relevance

IgE-mediated reactions

In a study, IgE antibody reactivity to oyster extracts in oyster-tolerant and oyster-sensitive subjects. Specific IgE determinations correlated weakly with skin prick tests. RAST® inhibition showed common antigenic structures in oyster and crustacea extracts. Oysters may eat crustacea larvae (1).

Other Topics

Oyster is a bivalve mollusk. The edible oysters belong to two genera, Ostrea and Crassostrea. Oysters in warm seas may take 18 months to reach market size, while in cooler seas, up to 5 years. Oyster has been reported as both an ingested and occupational allergen. Oysters are eaten fresh and canned, but also smoked. The Japanese have extensive off-bottom culture, especially in protected bays. The Chinese have all over the world exported a pungent sauce made from oyster extract and used for flavoring.

Oyster shell dust has been identified as an inhalant allergen in occupational asthma. Exercise-induced anaphylaxis has been reported after ingestion of smoked oysters (2).

One of the largest cultivations has taken place in Hiroshima Bay, Japan, since the 16th century. An early study from Japan identified oyster shell as an inhalant allergen in occupational bronchial asthma in workers at processing plants (3).

Molecular Aspects


Oyster and crustacea extracts show common antigenic structures. Some cross reactivity to blue mussel f37 can be expected.

Compiled By

Last Reviewed : June 2022

  1. Lehrer, SB; McCants, ML. Reactivity of IgE antibodies with crustacea and oyster allergens: Evidence for common antigenic structures. J Allergy Clin Immunol; 1987; 80: 133-139.
  2. Maulitz, RM; Pratt, DS; Schocket, AL. Exercise-induced anaphylactic reaction to shellfish. J Allergy Clin Immunol; 1979; 63: 433-434.
  3. Wada, S; Nishimoto, Y; Nakashima, T; Shigenobu, T; Onari, K; Awaya, M. Clinical observation of bronchial asthma in culture-oyster workers. Hiroshima J Med Sci; 1967; 16: 255-266.