Michael R. Broyles, PharmD – Director of Pharmacy and Lab Services
Abdominal pain and soreness, febrile
Significant medical history:
Chronic renal failure, peritoneal dialysis for five years, autoimmune disease, hypertension (HTN), diabetes mellitus (DM)
PCT = 1.26 μg/L, serum creatinine = 6.8 mg/dL, blood urea nitrogen (BUN) = 30 mg/dL, white blood count (WBC) = 12.6 x 103/µL, neutrophils 85.7 109/L, lactate 2.3 mmol/L, peritoneal dialysis effluent = clear
Peritonitis which was subsequently confirmed
Antibiotics started into peritoneal cavity, vancomycin and tobramycin with doses adjusted for trough values
PCT successfully trended down by approximately 50% daily.
“The normal baseline PCT in renal patients is typically a bit higher—we use 0.5 μg/L at my facility.”1 PCT is useful in patients on peritoneal dialysis, and trending is quite useful. Note that there was a steady decrease in PCT, by approximately 50% per day.
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