Case Study

Hemodialysis, Bacterial Pneumonia and Antibiotic De-escalation


Michael R. Broyles
PharmD – Director of Medical Affairs, Thermo Fisher Scientific



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Key Takeaways

Takeaway #1

Takeaway #1

Approximately 30% of PCT occurs renally.1



Takeaway #2

Takeaway #2

The elevated PCT level on admission was consistent with bacterial pneumonia. The patient was successfully treated with antibiotics.



Takeaway #3

Takeaway #3

The difference in PCT decrease was higher on dialysis days (approximately 50%) vs. non-dialysis days (approximately 30%). This is to be expected when there is renal impairment, PCT will only decrease approximately 30%.1



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References
  1. Meisner M. Procalcitonin-biochemistry and clinical diagnosis. Dresden (Germany): UNI-MED-Verlag; 2010.