Product References
Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Cancer discovery
Chen S,Vedula RS,Cuevas-Navarro A,Lu B,Hogg SJ,Wang E,Benbarche S,Knorr K,Kim WJ,Stanley RF,Cho H,Erickson C,Singer M,Cui D,Tittley S,Durham BH,Pavletich TS,Fiala E,Walsh MF,Inoue D,Monette S,Taylor J,Rosen N,McCormick F,Lindsley RC,Castel P,Abdel-Wahab O
100-64 was used in Cell Culture to reveal proteolysis of non-canonical RAS proteins as novel regulators of HSC self-renewal, define the function of RIT1 and LZTR1 mutations in leukemia, and identify means to overcome drug resistance due to LZTR1 downregulation.
Wed Oct 05 00:00:00 EDT 2022
Modeling human yolk sac hematopoiesis with pluripotent stem cells.
The Journal of experimental medicine
Atkins MH,Scarfò R,McGrath KE,Yang D,Palis J,Ditadi A,Keller GM
Mon Mar 07 00:00:00 EST 2022
Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation.
The Journal of experimental medicine
Ahmed N,Etzrodt M,Dettinger P,Kull T,Loeffler D,Hoppe PS,Chavez JS,Zhang Y,Camargo Ortega G,Hilsenbeck O,Nakajima H,Pietras EM,Schroeder T
Mon Jan 03 00:00:00 EST 2022
Patient-specific, re-engineered cardiomyocyte model confirms the circumstance-dependent arrhythmia risk associated with the African-specific common SCN5A polymorphism p.S1103Y: Implications for the increased sudden deaths observed in black individuals during the COVID-19 pandemic.
Heart rhythm
Hamrick SK,John Kim CS,Tester DJ,Giudicessi JR,Ackerman MJ
100-64 was used in Cell Culture to ascertain the effects of acidosis and hydroxychloroquine (HCQ) on the action potential duration (APD) in a patient-specific induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) model of p.S1103Y-SCN5A.
Sun May 01 00:00:00 EDT 2022
A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation.
RNA (New York, N.Y.)
Hug N,Aitken S,Longman D,Raab M,Armes H,Mann AR,Rio-Machin A,Fitzgibbon J,Rouault-Pierre K,Cáceres JF
100-64 was used in In vitro experiments to investigate NMD factors and the role of DNX34 in the spliceosome.
Thu Sep 01 00:00:00 EDT 2022
Single-chain tandem macrocyclic peptides as a scaffold for growth factor and cytokine mimetics.
Communications biology
Ito K,Matsuda Y,Mine A,Shikida N,Takahashi K,Miyairi K,Shimbo K,Kikuchi Y,Konishi A
Fri Jan 14 00:00:00 EST 2022
Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.
Cell discovery
Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L
100-64 was used in Cell Culture to demonstrate that interferon-mediated cell cycle control underlies the clinical efficacy of glucocorticoids.
Tue May 10 00:00:00 EDT 2022
Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms.
Cell stem cell
Van Egeren D,Escabi J,Nguyen M,Liu S,Reilly CR,Patel S,Kamaz B,Kalyva M,DeAngelo DJ,Galinsky I,Wadleigh M,Winer ES,Luskin MR,Stone RM,Garcia JS,Hobbs GS,Camargo FD,Michor F,Mullally A,Cortes-Ciriano I,Hormoz S
Thu Mar 04 00:00:00 EST 2021
Multiorgan failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes.
The Journal of clinical investigation
Nagamachi A,Kanai A,Nakamura M,Okuda H,Yokoyama A,Shinriki S,Matsui H,Inaba T
Mon Feb 15 00:00:00 EST 2021
Multiorgan failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes.
The Journal of clinical investigation
Nagamachi A,Kanai A,Nakamura M,Okuda H,Yokoyama A,Shinriki S,Matsui H,Inaba T
Mon Feb 15 00:00:00 EST 2021
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
The Journal of experimental medicine
Louka E,Povinelli B,Rodriguez-Meira A,Buck G,Wen WX,Wang G,Sousos N,Ashley N,Hamblin A,Booth CAG,Roy A,Elliott N,Iskander D,de la Fuente J,Fordham N,O'Byrne S,Inglott S,Norfo R,Salio M,Thongjuea S,Rao A,Roberts I,Mead AJ
Mon Feb 01 00:00:00 EST 2021
Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells.
The Journal of experimental medicine
Cova G,Taroni C,Deau MC,Cai Q,Mittelheisser V,Philipps M,Jung M,Cerciat M,Le Gras S,Thibault-Carpentier C,Jost B,Carlsson L,Thornton AM,Shevach EM,Kirstetter P,Kastner P,Chan S
Mon Oct 04 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Mon Jul 05 00:00:00 EDT 2021
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Developmental cell
Ma Y,Liu S,Gao J,Chen C,Zhang X,Yuan H,Chen Z,Yin X,Sun C,Mao Y,Zhou F,Shao Y,Liu Q,Xu J,Cheng L,Yu D,Li P,Yi P,He J,Geng G,Guo Q,Si Y,Zhao H,Li H,Banes GL,Liu H,Nakamura Y,Kurita R,Huang Y,Wang X,Wang F,Fang G,Engel JD,Shi L,Zhang YE,Yu J
100-64 was used in Sample Preparation (FC/FACS) to investigate pseudogene phenotypic effects.
Mon Feb 22 00:00:00 EST 2021
CXCL12-abundant reticular cells are the major source of IL-6 upon LPS stimulation and thereby regulate hematopoiesis.
Blood advances
Gerosa RC,Boettcher S,Kovtonyuk LV,Hausmann A,Hardt WD,Hidalgo J,Nombela-Arrieta C,Manz MG
Tue Dec 14 00:00:00 EST 2021
Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic.
Nature communications
Zhang X,Luo M,Dastagir SR,Nixon M,Khamhoung A,Schmidt A,Lee A,Subbiah N,McLaughlin DC,Moore CL,Gribble M,Bayhi N,Amin V,Pepi R,Pawar S,Lyford TJ,Soman V,Mellen J,Carpenter CL,Turka LA,Wickham TJ,Chen TF
Tue May 11 00:00:00 EDT 2021
Methylation of dual-specificity phosphatase 4 controls cell differentiation.
Cell reports
Su H,Jiang M,Senevirathne C,Aluri S,Zhang T,Guo H,Xavier-Ferrucio J,Jin S,Tran NT,Liu SM,Sun CW,Zhu Y,Zhao Q,Chen Y,Cable L,Shen Y,Liu J,Qu CK,Han X,Klug CA,Bhatia R,Chen Y,Nimer SD,Zheng YG,Iancu-Rubin C,Jin J,Deng H,Krause DS,Xiang J,Verma A,Luo M,Zhao X
Tue Jul 27 00:00:00 EDT 2021
In vitro expansion of fetal liver hematopoietic stem cells.
Scientific reports
Bhardwaj R,Kumar L,Chhabra D,Mehra NK,Sharma A,Mohanty S,Kochupillai V
Fri Jun 04 00:00:00 EDT 2021
Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation.
Nature communications
Georgolopoulos G,Psatha N,Iwata M,Nishida A,Som T,Yiangou M,Stamatoyannopoulos JA,Vierstra J
Tue Nov 23 00:00:00 EST 2021
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Nature communications
Velten L,Story BA,Hernández-Malmierca P,Raffel S,Leonce DR,Milbank J,Paulsen M,Demir A,Szu-Tu C,Frömel R,Lutz C,Nowak D,Jann JC,Pabst C,Boch T,Hofmann WK,Müller-Tidow C,Trumpp A,Haas S,Steinmetz LM
Mon Mar 01 00:00:00 EST 2021
Molecular and cellular basis of hyperassembly and protein aggregation driven by a rare pathogenic mutation in DDX3X.
iScience
de Castro Fonseca M,de Oliveira JF,Araujo BHS,Canateli C,do Prado PFV,Amorim Neto DP,Bosque BP,Rodrigues PV,de Godoy JVP,Tostes K,Filho HVR,Nascimento AFZ,Saito A,Tonoli CCC,Batista FAH,de Oliveira PSL,Figueira AC,Souza da Costa S,Krepischi ACV,Rosenberg C,Westfahl H,da Silva AJR,Franchini KG
Fri Aug 20 00:00:00 EDT 2021
Mitochondrial Metabolism as Target of the Neuroprotective Role of Erythropoietin in Parkinson's Disease.
Antioxidants (Basel, Switzerland)
Rey F,Ottolenghi S,Giallongo T,Balsari A,Martinelli C,Rey R,Allevi R,Giulio AMD,Zuccotti GV,Mazzucchelli S,Foresti R,Samaja M,Carelli S
100-64 was used in Sample Preparation to investigate use of erythropoietin to treat Parkinson’s.
Fri Jan 15 00:00:00 EST 2021
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
Cancer discovery
Su A,Ling F,Vaganay C,Sodaro G,Benaksas C,Dal Bello R,Forget A,Pardieu B,Lin KH,Rutter JC,Bassil CF,Fortin G,Pasanisi J,Antony-Debré I,Alexe G,Benoist JF,Pruvost A,Pikman Y,Qi J,Schlageter MH,Micol JB,Roti G,Cluzeau T,Dombret H,Preudhomme C,Fenouille N,Benajiba L,Golan HM,Stegmaier K,Lobry C,Wood KC,Itzykson R,Puissant A
100-64 was used in Cell Culture to investigate the effects of MTHFR for its therapeutic effects on acute myeloid leukemia.
Tue Dec 01 00:00:00 EST 2020
Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation.
Cell stem cell
Ortmann D,Brown S,Czechanski A,Aydin S,Muraro D,Huang Y,Tomaz RA,Osnato A,Canu G,Wesley BT,Skelly DA,Stegle O,Choi T,Churchill GA,Baker CL,Rugg-Gunn PJ,Munger SC,Reinholdt LG,Vallier L
100-64 was used in Cell Culture to investigate the variability in experimental reproducibility of pluripotent stem cell lines in mice.
Thu Sep 03 00:00:00 EDT 2020
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development.
Cell stem cell
Crosse EI,Gordon-Keylock S,Rybtsov S,Binagui-Casas A,Felchle H,Nnadi NC,Kirschner K,Chandra T,Tamagno S,Webb DJ,Rossi F,Anderson RA,Medvinsky A
100-64 was used in In vitro experiments to identify secreted signals underlying human HSC development, combining spatial transcriptomics analysis of dorsoventral polarized signaling in the aorta with gene expression profiling of sorted cell populations and single cells.
Thu Nov 05 00:00:00 EST 2020
Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells.
EMBO reports
Szade K,Zukowska M,Szade A,Nowak W,Skulimowska I,Ciesla M,Bukowska-Strakova K,Gulati GS,Kachamakova-Trojanowska N,Kusienicka A,Einwallner E,Kijowski J,Czauderna S,Esterbauer H,Benes V,L Weissman I,Dulak J,Jozkowicz A
Wed Feb 05 00:00:00 EST 2020
Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells.
EMBO reports
Szade K,Zukowska M,Szade A,Nowak W,Skulimowska I,Ciesla M,Bukowska-Strakova K,Gulati GS,Kachamakova-Trojanowska N,Kusienicka A,Einwallner E,Kijowski J,Czauderna S,Esterbauer H,Benes V,L Weissman I,Dulak J,Jozkowicz A
Wed Feb 05 00:00:00 EST 2020
Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins.
Nature communications
Pavani G,Laurent M,Fabiano A,Cantelli E,Sakkal A,Corre G,Lenting PJ,Concordet JP,Toueille M,Miccio A,Amendola M
Wed Jul 29 00:00:00 EDT 2020
Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells.
eLife
Cendrowski J,Kaczmarek M,Mazur M,Kuzmicz-Kowalska K,Jastrzebski K,Brewinska-Olchowik M,Kominek A,Piwocka K,Miaczynska M
100-64 was used in Cell Culture to investigate the role of the longer(L) and shorter(S) splicing variant of bone morphogenetic protein 2-inducible kinase(BMP2K) in endocytosis and cell differentiation.
Fri Aug 14 00:00:00 EDT 2020
Inhibition of red blood cell development by arsenic-induced disruption of GATA-1.
Scientific reports
Zhou X,Medina S,Bolt AM,Zhang H,Wan G,Xu H,Lauer FT,Wang SC,Burchiel SW,Liu KJ
Wed Nov 04 00:00:00 EST 2020
JTZ-951, an HIF prolyl hydroxylase inhibitor, suppresses renal interstitial fibroblast transformation and expression of fibrosis-related factors.
American journal of physiology. Renal physiology
Wakashima T,Tanaka T,Fukui K,Komoda Y,Shinozaki Y,Kobayashi H,Matsuo A,Nangaku M
Wed Jan 01 00:00:00 EST 2020
Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1.
Immunity
Tyrkalska SD,Pérez-Oliva AB,Rodríguez-Ruiz L,Martínez-Morcillo FJ,Alcaraz-Pérez F,Martínez-Navarro FJ,Lachaud C,Ahmed N,Schroeder T,Pardo-Sánchez I,Candel S,López-Muñoz A,Choudhuri A,Rossmann MP,Zon LI,Cayuela ML,García-Moreno D,Mulero V
Tue Jul 16 00:00:00 EDT 2019
PRDM16s transforms megakaryocyte-erythroid progenitors into myeloid leukemia-initiating cells.
Blood
Hu T,Morita K,Hill MC,Jiang Y,Kitano A,Saito Y,Wang F,Mao X,Hoegenauer KA,Morishita K,Martin JF,Futreal PA,Takahashi K,Nakada D
Thu Aug 15 00:00:00 EDT 2019
Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies.
Blood
Sasca D,Yun H,Giotopoulos G,Szybinski J,Evan T,Wilson NK,Gerstung M,Gallipoli P,Green AR,Hills R,Russell N,Osborne CS,Papaemmanuil E,Göttgens B,Campbell P,Huntly BJP
Thu Dec 12 00:00:00 EST 2019
TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.
Cell stem cell
Yamashita M,Passegué E
100-64 was used in Cell Culture to reveal several TNF-α-mediated pro-survival mechanisms unique to HSCs, highlight an important role for necroptosis in HSC killing, and establish TNF-α as a major pro-survival and pro-regeneration factor for HSCs.
Thu Sep 05 00:00:00 EDT 2019
Gene correction for SCID-X1 in long-term hematopoietic stem cells.
Nature communications
Pavel-Dinu M,Wiebking V,Dejene BT,Srifa W,Mantri S,Nicolas CE,Lee C,Bao G,Kildebeck EJ,Punjya N,Sindhu C,Inlay MA,Saxena N,DeRavin SS,Malech H,Roncarolo MG,Weinberg KI,Porteus MH
100-64 was used in In vitro experiments to evaluate the use of SCID-X1 in targeting the cDNA in human long-term hematopoietic stem cells.
Tue Apr 09 00:00:00 EDT 2019
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis.
Nature communications
Kuppers DA,Arora S,Lim Y,Lim AR,Carter LM,Corrin PD,Plaisier CL,Basom R,Delrow JJ,Wang S,Hansen He H,Torok-Storb B,Hsieh AC,Paddison PJ
Thu Oct 10 00:00:00 EDT 2019
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Immunity
Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z
Tue Apr 17 00:00:00 EDT 2018
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
The Journal of clinical investigation
Chennupati V,Veiga DF,Maslowski KM,Andina N,Tardivel A,Yu EC,Stilinovic M,Simillion C,Duchosal MA,Quadroni M,Roberts I,Sankaran VG,MacDonald HR,Fasel N,Angelillo-Scherrer A,Schneider P,Hoang T,Allam R
Mon Apr 02 00:00:00 EDT 2018
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
The Journal of clinical investigation
Chennupati V,Veiga DF,Maslowski KM,Andina N,Tardivel A,Yu EC,Stilinovic M,Simillion C,Duchosal MA,Quadroni M,Roberts I,Sankaran VG,MacDonald HR,Fasel N,Angelillo-Scherrer A,Schneider P,Hoang T,Allam R
Mon Apr 02 00:00:00 EDT 2018
Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy.
The Journal of clinical investigation
Zhang P,He F,Bai J,Yamamoto S,Chen S,Zhang L,Sheng M,Zhang L,Guo Y,Man N,Yang H,Wang S,Cheng T,Nimer SD,Zhou Y,Xu M,Wang QF,Yang FC
Mon Dec 03 00:00:00 EST 2018
Revealing nascent proteomics in signaling pathways and cell differentiation.
Proceedings of the National Academy of Sciences of the United States of America
Forester CM,Zhao Q,Phillips NJ,Urisman A,Chalkley RJ,Oses-Prieto JA,Zhang L,Ruggero D,Burlingame AL
Tue Mar 06 00:00:00 EST 2018
Identification of a Multipotent Progenitor Population in the Spleen That Is Regulated by NR4A1.
Journal of immunology (Baltimore, Md. : 1950)
Mumau MD,Vanderbeck AN,Lynch ED,Golec SB,Emerson SG,Punt JA
Thu Feb 01 00:00:00 EST 2018
NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells.
Nature communications
Uenishi GI,Jung HS,Kumar A,Park MA,Hadland BK,McLeod E,Raymond M,Moskvin O,Zimmerman CE,Theisen DJ,Swanson S,J Tamplin O,Zon LI,Thomson JA,Bernstein ID,Slukvin II
Tue May 08 00:00:00 EDT 2018
Proteinase 3 Limits the Number of Hematopoietic Stem and Progenitor Cells in Murine Bone Marrow.
Stem cell reports
Karatepe K,Zhu H,Zhang X,Guo R,Kambara H,Loison F,Liu P,Yu H,Ren Q,Luo X,Manis J,Cheng T,Ma F,Xu Y,Luo HR
Tue Nov 13 00:00:00 EST 2018
Reconstruction of complex single-cell trajectories using CellRouter.
Nature communications
Lummertz da Rocha E,Rowe RG,Lundin V,Malleshaiah M,Jha DK,Rambo CR,Li H,North TE,Collins JJ,Daley GQ
Thu Mar 01 00:00:00 EST 2018
Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis.
Cell discovery
Rothberg JLM,Maganti HB,Jrade H,Porter CJ,Palidwor GA,Cafariello C,Battaion HL,Khan ST,Perkins TJ,Paulson RF,Ito CY,Stanford WL
Thu Aug 17 00:00:00 EDT 2023
Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells.
Scientific reports
MacLean GA,McEldoon J,Huang J,Allred J,Canver MC,Orkin SH
Tue May 22 00:00:00 EDT 2018
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells.
Stem cell reports
Kauts ML,De Leo B,Rodríguez-Seoane C,Ronn R,Glykofrydis F,Maglitto A,Kaimakis P,Basi M,Taylor H,Forrester L,Wilkinson AC,Göttgens B,Saunders P,Dzierzak E
Tue Oct 09 00:00:00 EDT 2018
Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates.
Stem cells translational medicine
Gori JL,Butler JM,Kunar B,Poulos MG,Ginsberg M,Nolan DJ,Norgaard ZK,Adair JE,Rafii S,Kiem HP
Wed Mar 01 00:00:00 EST 2017
Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors.
Stem cell reports
Wen W,Zhang JP,Xu J,Su RJ,Neises A,Ji GZ,Yuan W,Cheng T,Zhang XB
Tue Jun 14 00:00:00 EDT 2016
Cyclic AMP Signaling through Epac Axis Modulates Human Hemogenic Endothelium and Enhances Hematopoietic Cell Generation.
Stem cell reports
Saxena S,Rönn RE,Guibentif C,Moraghebi R,Woods NB
Tue May 10 00:00:00 EDT 2016
T-cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung.
Blood
Iriguchi S,Kikuchi N,Kaneko S,Noguchi E,Morishima Y,Matsuyama M,Yoh K,Takahashi S,Nakauchi H,Ishii Y
Thu Jan 08 00:00:00 EST 2015
Insulin-InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages.
The Journal of experimental medicine
Xia P,Wang S,Du Y,Huang G,Satoh T,Akira S,Fan Z
Mon Dec 14 00:00:00 EST 2015
Pak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiation.
Stem cells (Dayton, Ohio)
Zeng Y,Broxmeyer HE,Staser K,Chitteti BR,Park SJ,Hahn S,Cooper S,Sun Z,Jiang L,Yang X,Yuan J,Kosoff R,Sandusky G,Srour EF,Chernoff J,Clapp DW
Fri May 01 00:00:00 EDT 2015
Bmi1 promotes erythroid development through regulating ribosome biogenesis.
Stem cells (Dayton, Ohio)
Gao R,Chen S,Kobayashi M,Yu H,Zhang Y,Wan Y,Young SK,Soltis A,Yu M,Vemula S,Fraenkel E,Cantor A,Antipin Y,Xu Y,Yoder MC,Wek RC,Ellis SR,Kapur R,Zhu X,Liu Y
Sun Mar 01 00:00:00 EST 2015
Bmi1 promotes erythroid development through regulating ribosome biogenesis.
Stem cells (Dayton, Ohio)
Gao R,Chen S,Kobayashi M,Yu H,Zhang Y,Wan Y,Young SK,Soltis A,Yu M,Vemula S,Fraenkel E,Cantor A,Antipin Y,Xu Y,Yoder MC,Wek RC,Ellis SR,Kapur R,Zhu X,Liu Y
Sun Mar 01 00:00:00 EST 2015
Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion.
Scientific reports
Xie XQ,Yang P,Zhang Y,Zhang P,Wang L,Ding Y,Yang M,Tong Q,Cheng H,Ji Q,McGuire T,Yuan W,Cheng T,Gao Y
Fri Dec 18 00:00:00 EST 2015
Fancb deficiency impairs hematopoietic stem cell function.
Scientific reports
Du W,Amarachintha S,Erden O,Wilson A,Meetei AR,Andreassen PR,Namekawa SH,Pang Q
Fri Dec 11 00:00:00 EST 2015
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Mon Sep 22 00:00:00 EDT 2014
Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling.
Journal of immunology (Baltimore, Md. : 1950)
Balmer ML,Schürch CM,Saito Y,Geuking MB,Li H,Cuenca M,Kovtonyuk LV,McCoy KD,Hapfelmeier S,Ochsenbein AF,Manz MG,Slack E,Macpherson AJ
Sat Nov 15 00:00:00 EST 2014
Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages.
Stem cells (Dayton, Ohio)
Schenke-Layland K,Rhodes KE,Angelis E,Butylkova Y,Heydarkhan-Hagvall S,Gekas C,Zhang R,Goldhaber JI,Mikkola HK,Plath K,MacLellan WR
Sun Jun 01 00:00:00 EDT 2008