HOXD1 Proteins

Protein Information

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA1 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.

Synonyms

BSAS; homeo box 4G; homeo box A1; homeo box D1; homeobox 1F; homeobox A1; homeobox D1; homeobox protein Hox-4.9; Homeobox protein Hox-D1; homeobox protein Hox-GG; HOX1; HOX1F; HOX2I; HOX4; Hox-4.7; Hox-4.9; HOX4G; HOXA1; Hoxd1; Hoxd-1; MGC45232