In an interview discussing the design of UK Biobank’s whole-genome array, Professor Mark McCarthy of University of Oxford, UK, commented:
“At the common variant level, the set of tagSNPs that you might want to select to most efficiently cover the genome will differ from population to population. This will matter even more as we focus more on functional alleles that are more likely to be rare and ethnicity-specific.”
You can download the full interview with Professor McCarthy to see how UK Biobank solved this challenge.
To learn more about Axiom Biobank Genotyping Solution, please visit the product web page.