New Molecular Probes® Products

Beautiful results again and again

Molecular Probes® products represent the broadest range of fluorescent reagents available for imaging, flow cytometry, and microplate applications. We are committed to expanding that product range through our in-house development and our collaborations, to help keep you at the forefront of life science research. Listed below are just some of the products that we introduced during the last six months.

The Attune® NxT Acoustic Focusing Cytometer is the next generation in flow cytometry. Retaining all of the benefits of its predecessor (compact size, rapid processing of dilute samples, and the largest range of sample input flow rates), the Attune® NxT cytometer now offers more lasers (up to 4) and more detection channels (up to 16) to increase flexibility in reagent selection and reduce compensation scenarios without sacrificing the superior performance, reliability, and robustness of the instrument. The Attune® NxT cytometer is designed to accommodate most experimental analyzer applications conducted in the core lab, with a price point to fit individual lab budgets.

• Learn more about the Attune® NxT Acoustic Focusing Cytometer
  

The new Countess® II FL Automated Cell Counter is a benchtop assay platform equipped with state-of-the-art optics and image analysis software for rapid assessment of cells in suspension. With 3-channel flexibility—brightfield and two optional fluorescence channels—researchers can count cells, monitor fluorescent protein expression, and measure cell viability.

This system offers:

• Flexibility—customizable fluorescent channels using EVOS® Light Cubes
• Value—reusable hemocytometer reduces consumable costs
• Precision—autofocus to remove user variation
• Simplicity—easy-to-use capacitive touch screen interface

See the new Countess® II FL Automated Cell Counter in action

The Qubit® 3.0 Fluorometer is a benchtop fluorometer that can be used to quantify DNA, RNA, microRNA, and protein using the highly sensitive and accurate fluorescence-based Qubit® quantitation assays. Key features of this third-generation fluorometer include:

• Powerful dual-core processor that quickly and accurately quantifies DNA, RNA, and protein in less than 5 seconds per sample
• Assays use as little as 1 μL of sample and rely on dyes selective for dsDNA, RNA, or protein, minimizing the effects of contaminants such as degraded DNA or RNA
• Effective data management, with the ability to store up to 1,000 sample results
• Large 5.7-inch, state-of-the-art color touch screen for easy workflow navigation
• Small footprint, saving valuable space on your lab bench
• Ability to personalize your Qubit® fluorometer with the assays you run most often

Find out more about the Qubit® 3.0 Fluorometer

Image-iT® Hypoxia Reagent is a live-cell permeable compound, which increases fluorescence in environments with low oxygen concentrations. The reagent is fluorogenic when atmospheric oxygen levels are less than 5%, and shows real-time response to oxygen levels in live cells by increasing the signal with reduced oxygen. These properties make this reagent an ideal tool for detecting hypoxic conditions around tumor cells, 3D cultures, spheroids, neurons, and other live samples.

ProLong® Diamond and SlowFade® Diamond antifade reagents deliver all the performance of ProLong® and SlowFade® Gold reagents with Alexa Fluor® dyes. In addition, they provide protection for traditional dyes and fluorescent proteins. ProLong® and SlowFade® Diamond reagents are superior antifade mountants, offering protection across the visible and IR spectrum.

• Learn more about antifade mountants

The AbC™ Total Antibody Compensation Bead Kit is designed to provide a consistent, accurate, and simple-to-use technique for the setting of flow cytometry compensation when using fluorophore-conjugated mouse, rat, hamster, or rabbit antibodies with any laser in flow cytometry.

• Broadest multispecies reactivity—for use with all isotypes of mouse, rat, hamster, and rabbit antibody conjugates
• Brightest signal—most sensitive antibody-capture beads available
• Maximum laser compatibility—for use with all lasers
  

The mouse anti-human CD8a (clone OKT8) antibody is reactive to the human CD8a, known as CD8a or CD8 alpha. When expressed as a heterodimer with a second chain known as CD8b or CD8 beta, the resulting CD8 acts as a coreceptor for antigen recognition and subsequent T cell activation, which is initiated upon the binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. We have expanded the number of fluorescent conjugates of this antibody to allow you more flexibility in your experiment design.

• See all of our CD8a antibodies

WesternDot® antibodies deliver superior signal to-noise ratios and exhibit comparable sensitivity to ECL-based chemiluminescent methods in western blot applications. No stripping and reprobing, or multiple blots, are required for multiple protein detection as commonly practiced with ECL or colorimetric detection. Different colors of WesternDot® antibodies can be applied to a single blot and multiple proteins detected simultaneously using standard gel or blot imaging platforms. Features include:

• Reduce time to result—no secondary antibody needed, eliminating cumbersome HRP and ECL optimization
• Easy to switch—WesternDot® antibodies use standard membranes, blocking solutions, and buffers
• Up to 3-color detection—combine WesternDot® 655 with WesternDot® 585 and WesternDot® 800 antibodies

Learn more about the advantages of multiplexed Western detection