Antibodies or other ligands can be coupled onto the beads for affinity protein capture (click to enlarge).
A wide range of products—flexibility for your research
Invitrogen Surface-activated Dynabeads are available in different sizes, with a hydrophobic or hydrophilic nature, and with a variety of surface chemistries (see Table 1 below). To obtain the best possible results it is important to choose a size and surface of the Dynabeads suited for your application. The choice will depend on the nature of the ligand. In most applications several Dynabeads products can be used.
Table 1. Choose the right surface-activated Dynabeads for your application.
|Dynabeads Amine||Dynabeads Epoxy|
|Antibody||Low MW antigen1 or peptide|
|Protein or antibody|
|Antibody Fragment||Phage1 or antibody|
|Protein||Phage or carbohydrate|
|Peptide||Phage1 or antibody|
|Low MV antigen||Antibody|
|Nucleic acids, oligonucleotide, aptamer, PNA||Nucleic acid binding proteins1||4|
|DNA1, RNA1 or PCR amplicons1||4|
|Enzyme||Substrate or target for enzyme degradation|
|Organic chemistry derivatization, including introduction of new functional groups|
Best product choice for listed ligand and target.
Alternative choice for listed ligand and target.
Can be used for listed ligand and target.
1 Dynabeads pre-coupled with streptavidin may be the best product choice.
2 Dynabeads M-450 Epoxy.
3 Dynabeads M-450 Epoxy are recommended for isolation, stimulation, and expansion of cells.
4 Bifunctional crosslinkers may be introduced to immobilize oligonucleotides onto the surface of Dynabeads Amine.
Surface-activated Dynabeads product list
For Research Use Only. Not for use in diagnostic procedures.