Shop All Single-Use BioProcessing Systems
HyPerforma™ 5:1 Single-Use Bioreactor, jacketed, AC motor, load cells (Thermo Scientific™)
This 500 L Thermo Scientific Single-Use Bioreactor (S.U.B.), water-jacketed, with AC motor and load cells, is designed using traditional stainless-steel bioreactor principles to ensure optimal cell culture performance. The S.U.B. is a fully functional bioreactor vessel including single-use sterile contact surfaces for mixing, venting, sparging, and temperature sensing. The complete line of S.U.B.s include 50, 100, 250, 500, 1000, and 2000 L sizes that ensure consistent scalability from pilot-scale studies, pre-clinical to commercial production.
Features:
• Unique proprietary mixing system that enables conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC)
• Largest qualified standard component library, which allows for customization of S.U.B. BPCs
• Minimized vessel footprint and reduced hold-up volumes
• Offered with AC or DC motors designed for precise agitation control
• Optional cable management tree provides line set and cabling organization for ease of use
• Load cells offered as standard feature with analog or digital communication options
• Option to use industry-leading single-use and traditional sensors for pH, DO, and pressure monitoring
• Option to choose the bioreactor vessel as a stand-alone system or a complete turnkey system with dedicated controls from either the Finesse™ or Applikon™ families of control systems for bioproduction. These systems work on PC, Delta V™, Allen-Bradley™, or Siemens™ software platforms.
• Updated 5:1 mixing turn-down ratio in combination with patented cross-flow sparger technology introduces gas just above liquid’s surface—to facilitate efficient mass transfer CO2 stripping, and reduce bubble sparging and associated foam damage to cells. This feature allows customers to do more with fewer vessels—which improves productivity and reduces costs simultaneously.
Applications of the Thermo Scientific S.U.B. include:
• Batch, fed batch, and perfusion cultures
• Suspension and microcarrier cultures
• Proven for various cell lines such as CHO, Sp2/0 hybridoma, PER.C6, HEK293, Vero, MDCK, etc.
Features:
• Unique proprietary mixing system that enables conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC)
• Largest qualified standard component library, which allows for customization of S.U.B. BPCs
• Minimized vessel footprint and reduced hold-up volumes
• Offered with AC or DC motors designed for precise agitation control
• Optional cable management tree provides line set and cabling organization for ease of use
• Load cells offered as standard feature with analog or digital communication options
• Option to use industry-leading single-use and traditional sensors for pH, DO, and pressure monitoring
• Option to choose the bioreactor vessel as a stand-alone system or a complete turnkey system with dedicated controls from either the Finesse™ or Applikon™ families of control systems for bioproduction. These systems work on PC, Delta V™, Allen-Bradley™, or Siemens™ software platforms.
• Updated 5:1 mixing turn-down ratio in combination with patented cross-flow sparger technology introduces gas just above liquid’s surface—to facilitate efficient mass transfer CO2 stripping, and reduce bubble sparging and associated foam damage to cells. This feature allows customers to do more with fewer vessels—which improves productivity and reduces costs simultaneously.
Applications of the Thermo Scientific S.U.B. include:
• Batch, fed batch, and perfusion cultures
• Suspension and microcarrier cultures
• Proven for various cell lines such as CHO, Sp2/0 hybridoma, PER.C6, HEK293, Vero, MDCK, etc.
HyPerforma™ Single-Use Mixer (S.U.M.), 50L, Jacketed, 240VAC, AC Motor, with Load Cell (Thermo Scientific™)
The 50 L Thermo Scientific™ HyPerforma™ Single-Use Mixer (S.U.M.), non-jacketed, 240VAC, AC motor, with load cell, is designed using proven engineered mixer platform principles and is used for upstream and downstream mixing applications. The HyPerforma S.U.M. offers a more ergonomic and efficient user experience. The complete line of HyPerforma S.U.M.s includes 50, 100, 200, 500, 1,000 and 2,000 L sizes that helps ensure consistent scalability while providing a number of application usages from powder media and buffer hydration to advanced downstream harvest and intermediate pooling steps.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
BioProcess Container (BPC), 200L, for HyPerforma™ Single-Use Mixer, powder-to-liquid, CX5-14 film, 3 ports (Thermo Scientific™)
The 200L Thermo Scientific™ Bioprocess Containers (BPC), for powder-to-liquid mixing, is composed of CX5-14 single web, multi-layer plastic film and includes 3 ports.
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
HyPerforma™ 5:1 Single-Use Bioreactor, jacketed, AC motor, load cells (Thermo Scientific™)
This 500 L Thermo Scientific Single-Use Bioreactor (S.U.B.), water-jacketed, 120VAC, with AC motor, E-box, and analog load cells, is designed using traditional stainless-steel bioreactor principles to ensure optimal cell culture performance. The S.U.B. is a fully functional bioreactor vessel including single-use sterile contact surfaces for mixing, venting, sparging, and temperature sensing. The complete line of S.U.B.s include 50, 100, 250, 500, 1000, and 2000 L sizes that ensure consistent scalability from pilot-scale studies, pre-clinical to commercial production.
Features:
• Unique proprietary mixing system that enables conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC)
• Largest qualified standard component library, which allows for customization of S.U.B. BPCs
• Minimized vessel footprint and reduced hold-up volumes
• Offered with AC or DC motors designed for precise agitation control
• Optional cable management tree provides line set and cabling organization for ease of use
• Load cells offered as standard feature with analog or digital communication options
• Option to use industry-leading single-use and traditional sensors for pH, DO, and pressure monitoring
• Option to choose the bioreactor vessel as a stand-alone system or a complete turnkey system with dedicated controls from either the Finesse™ or Applikon™ families of control systems for bioproduction. These systems work on PC, Delta V™, Allen-Bradley™, or Siemens™ software platforms.
• Updated 5:1 mixing turn-down ratio in combination with patented cross-flow sparger technology introduces gas just above liquid’s surface—to facilitate efficient mass transfer CO2 stripping, and reduce bubble sparging and associated foam damage to cells. This feature allows customers to do more with fewer vessels—which improves productivity and reduces costs simultaneously.
Applications of the Thermo Scientific S.U.B. include:
• Batch, fed batch, and perfusion cultures
• Suspension and microcarrier cultures
• Proven for various cell lines such as CHO, Sp2/0 hybridoma, PER.C6, HEK293, Vero, MDCK, etc.
Features:
• Unique proprietary mixing system that enables conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC)
• Largest qualified standard component library, which allows for customization of S.U.B. BPCs
• Minimized vessel footprint and reduced hold-up volumes
• Offered with AC or DC motors designed for precise agitation control
• Optional cable management tree provides line set and cabling organization for ease of use
• Load cells offered as standard feature with analog or digital communication options
• Option to use industry-leading single-use and traditional sensors for pH, DO, and pressure monitoring
• Option to choose the bioreactor vessel as a stand-alone system or a complete turnkey system with dedicated controls from either the Finesse™ or Applikon™ families of control systems for bioproduction. These systems work on PC, Delta V™, Allen-Bradley™, or Siemens™ software platforms.
• Updated 5:1 mixing turn-down ratio in combination with patented cross-flow sparger technology introduces gas just above liquid’s surface—to facilitate efficient mass transfer CO2 stripping, and reduce bubble sparging and associated foam damage to cells. This feature allows customers to do more with fewer vessels—which improves productivity and reduces costs simultaneously.
Applications of the Thermo Scientific S.U.B. include:
• Batch, fed batch, and perfusion cultures
• Suspension and microcarrier cultures
• Proven for various cell lines such as CHO, Sp2/0 hybridoma, PER.C6, HEK293, Vero, MDCK, etc.
HyPerforma™ Single-Use Mixer (S.U.M.), 50L, Non-Jacketed, 240VAC, AC Motor, with Load Cell (Thermo Scientific™)
The 50 L Thermo Scientific™ HyPerforma™ Single-Use Mixer (S.U.M.), jacketed, 240VAC, AC motor, with load cell, is designed using proven engineered mixer platform principles and is used for upstream and downstream mixing applications. The HyPerforma S.U.M. offers a more ergonomic and efficient user experience. The complete line of HyPerforma S.U.M.s includes 50, 100, 200, 500, 1,000 and 2,000 L sizes that helps ensure consistent scalability while providing a number of application usages from powder media and buffer hydration to advanced downstream harvest and intermediate pooling steps.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
inSITE™ Integrity Testing System, single-channel, Europe (Thermo Scientific™)
The Thermo Scientific™ inSITE™ Integrity Testing System is a single-channel (Europe), AC-powered quality assurance testing system. The inSITE system uses pressure decay measurements to detect leaks that can occur between the warehouse and the clean room floor, or from improper handling and loading procedures. The system can also be used to manage overall quality of bioprocess containers up to the liquid filling cycle.
Features
• Inflation cycle—assists users in loading Thermo Scientific™ BioProcess Containers (BPCs) with minimal interaction, helping to reduce the risk of handling errors
• Gross leak detection—finds small leaks (100 μm–1,000 μm) and confirms connection and setup of the BPC
• Fine leak detection—unique for each tank and BPC assembly
• Liquid filling cycle—moderates the internal pressure within the BPC while fluid is being introduced
• Inflation port—separate port that allows all other ports to remain closed
• Wireless PC
• Label printer
• Bar code scanner
• USB port
Applications
• Point-of-use integrity testing up to 5,000 L
• Gross and fine leak detection
• Guided validation setup
• Improved loading and placement in tanks
• Internal pressure regulation while fluid is being introduced
• Comparative pressure data analysis
inSITE specifications
• Size: 66 x 74 x 147 cm (26 x 29 x 58 in.)
• Weight: 124.7 kg (275 lbs.)
• Power requirements: 220 VAC, 15A, 50 Hz
• Maximum operating pressure: 25−40 mbar
• Room temperature: 65−75°F (18−24°C)
• Maximum measurable volume: 5,000 L
Features
• Inflation cycle—assists users in loading Thermo Scientific™ BioProcess Containers (BPCs) with minimal interaction, helping to reduce the risk of handling errors
• Gross leak detection—finds small leaks (100 μm–1,000 μm) and confirms connection and setup of the BPC
• Fine leak detection—unique for each tank and BPC assembly
• Liquid filling cycle—moderates the internal pressure within the BPC while fluid is being introduced
• Inflation port—separate port that allows all other ports to remain closed
• Wireless PC
• Label printer
• Bar code scanner
• USB port
Applications
• Point-of-use integrity testing up to 5,000 L
• Gross and fine leak detection
• Guided validation setup
• Improved loading and placement in tanks
• Internal pressure regulation while fluid is being introduced
• Comparative pressure data analysis
inSITE specifications
• Size: 66 x 74 x 147 cm (26 x 29 x 58 in.)
• Weight: 124.7 kg (275 lbs.)
• Power requirements: 220 VAC, 15A, 50 Hz
• Maximum operating pressure: 25−40 mbar
• Room temperature: 65−75°F (18−24°C)
• Maximum measurable volume: 5,000 L
BioProcess Container (BPC), 200L, for HyPerforma™ Single-Use Mixer, liquid-to-liquid, CX5-14 film, 3 ports (Thermo Scientific™)
The 200L Thermo Scientific™ Bioprocess Containers (BPC) for liquid-to-liquid mixing, is composed of CX5-14 single web, multi-layer plastic film and includes 3 ports.
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
BioProcess Container (BPC), 50L, for HyPerforma™ Single-Use Mixer, powder-to-liquid, Aegis5-14 film, 0 ports (Thermo Scientific™)
The 50L Thermo Scientific™ Bioprocess Containers (BPC) for powder-to-liquid mixing, is composed of Aegis 5-14 single web, multi-layer plastic film and includes 0 ports.
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
HyPerforma™ Single-Use Mixer (S.U.M.), 100L, Non-Jacketed, DC Motor, with Load Cell (Thermo Scientific™)
The 100 L Thermo Scientific™ HyPerforma™ Single-Use Mixer (S.U.M.), non-jacketed, DC motor, with load cell, is designed using proven engineered mixer platform principles and is used for upstream and downstream mixing applications. The HyPerforma S.U.M. offers a more ergonomic and efficient user experience. The complete line of HyPerforma S.U.M.s includes 50, 100, 200, 500, 1,000 and 2,000 L sizes that helps ensure consistent scalability while providing a number of application usages from powder media and buffer hydration to advanced downstream harvest and intermediate pooling steps.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
Precise™ Filling System BioProcess Container (BPC), ASI™ 28 film, 2 ports, MPC insert connector and fill connector (Thermo Scientific™)
The 10 L Thermo Scientific™ Precise™ Single-Use Filling System BioProcess Container (BPC) and tubing assembly create a clean, efficient method of filling. The filling line can be configured to attach to any fluid source, such as a single-use mixer, or holding tanks. The filling system BPCs can also be configured to make the system fit your application.
The two-port BPCs range in size from 100 mL to 2 L, and can be used for applications that require separate filling and dispensing ports. The standard luer connector on the secondary dispensing port can be used with a syringe or port adapter. All standard BPCs can be customized for unique applications. BPC includes 2 ports (1 fill connector with barb, 1 luer/cap body with barb.)
Key benefits of the Precise Single-Use Filling System include:
• Improved fluid transfer
• Accurate volumetric filling
• Weight scale integration capabilities
• Small footprint design
• Easy to clean
• Predefined filling processes
Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, and cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, and steam-to and steam-through connectors
• Filters (used for bioburden reduction)—sterilization grade filters and vent filters
• Tubing—thermoplastic elastomers and platinum-cured silicone
• Sample ports—septum-style and needle-free ports
• Clamps—sliders, pinch, and crimp bands
The two-port BPCs range in size from 100 mL to 2 L, and can be used for applications that require separate filling and dispensing ports. The standard luer connector on the secondary dispensing port can be used with a syringe or port adapter. All standard BPCs can be customized for unique applications. BPC includes 2 ports (1 fill connector with barb, 1 luer/cap body with barb.)
Key benefits of the Precise Single-Use Filling System include:
• Improved fluid transfer
• Accurate volumetric filling
• Weight scale integration capabilities
• Small footprint design
• Easy to clean
• Predefined filling processes
Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
• Fittings—straight, reducing, elbow, T-style, X-style, and cross-style
• Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, and steam-to and steam-through connectors
• Filters (used for bioburden reduction)—sterilization grade filters and vent filters
• Tubing—thermoplastic elastomers and platinum-cured silicone
• Sample ports—septum-style and needle-free ports
• Clamps—sliders, pinch, and crimp bands
BioProcess Container (BPC), 50L, for HyPerforma™ Single-Use Mixer, powder-to-liquid, CX5-14 film, 3 ports (Thermo Scientific™)
The 50L Thermo Scientific™ Bioprocess Containers (BPC) for liquid-to-liquid mixing, is composed of Aegis 5-14 single web, multi-layer plastic film and includes 3 ports.
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
BioProcess Container (BPC), 200L, for HyPerforma™ Single-Use Mixer, powder-to-liquid, Aegis5-14 film, 0 ports (Thermo Scientific™)
The 200L Thermo Scientific™ Bioprocess Containers (BPC) for powder-to-liquid mixing, is composed of Aegis 5-14 single web, multi-layer plastic film and includes 0 ports.
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability
HyPerforma™ Single-Use Mixer (S.U.M.), 100L, Jacketed, 240 VAC, AC Motor, with Load Cell (Thermo Scientific™)
The 100 L Thermo Scientific™ HyPerforma™ Single-Use Mixer (S.U.M.), jacketed, 240VAC, AC motor, with load cell, is designed using proven engineered mixer platform principles and is used for upstream and downstream mixing applications. The HyPerforma S.U.M. offers a more ergonomic and efficient user experience. The complete line of HyPerforma S.U.M.s includes 50, 100, 200, 500, 1,000 and 2,000 L sizes that helps ensure consistent scalability while providing a number of application usages from powder media and buffer hydration to advanced downstream harvest and intermediate pooling steps.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
HyPerforma™ Single-Use Mixer (S.U.M.), 100L, Jacketed, DC Motor, with Load Cell (Thermo Scientific™)
The 100 L Thermo Scientific™ HyPerforma™ Single-Use Mixer (S.U.M.), jacketed, DC motor, with load cell, is designed using proven engineered mixer platform principles and is used for upstream and downstream mixing applications. The HyPerforma S.U.M. offers a more ergonomic and efficient user experience. The complete line of HyPerforma S.U.M.s includes 50, 100, 200, 500, 1,000 and 2,000 L sizes that helps ensure consistent scalability while providing a number of application usages from powder media and buffer hydration to advanced downstream harvest and intermediate pooling steps.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
HyPerforma™ Single-Use Mixer (S.U.M.), 1000L, Non-Jacketed, DC Motor, with Load Cell (Thermo Scientific™)
The 1000 L Thermo Scientific™ HyPerforma™ Single-Use Mixer (S.U.M.), non-jacketed, DC motor, with load cell, is designed using proven engineered mixer platform principles and is used for upstream and downstream mixing applications. The HyPerforma S.U.M. offers a more ergonomic and efficient user experience. The complete line of HyPerforma S.U.M.s includes 50, 100, 200, 500, 1,000 and 2,000 L sizes that helps ensure consistent scalability while providing a number of application usages from powder media and buffer hydration to advanced downstream harvest and intermediate pooling steps.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
Features:
• Unique proprietary mixing system that provides conventional overhead mixing while maintaining sterility and integrity of the S.U.B. BioProcess Container (BPC).
• Minimized vessel footprint and reduced hold-up volume.
• Simplified bag loading with a vertical access door (available on 500 L, 1,000 L sizes and on 2,000 L S.U.M.).
• Cable management system provides greater organization for electrical cables, tubing and line sets.
• Dedicated adjustable tool holder keeps necessary tools available for convenience.
• Mixer vessel is offered with non-jacketed (no heat transfer) or water jacket (vessel side and bottom). Water jacket to be used with separate external temperature control unit for heat transfer requirement.
• Offered with choice of AC motor or DC motor with precise agitation control. Brushless DC motor includes encoder feedback to help improve RPM accuracy and is GFCI-compatible. (Electrical box not available with DC motors).
• Three load cells weighing systems enable accurate batch weight monitoring.
• Option to use probes for temperature, pH, conductivity and pressure monitoring.
• Electrical box with communication cable that provides output signals to customer plant controller.
• S.U.M. BPCs offered in CX5-14 and Aegis5-14 Films.
Applications of the Thermo Scientific HyPerforma S.U.M. include:
• Powder media hydration.
• Liquid media concentrate dilution.
• Harvest hold tank.
• Viral inactivation.
• Downstream intermediate pooling.
• Final product hold and additive suspension.
