Shop All Receptors & Cell Surface Markers

CD274 (PDL1) Recombinant Human Protein, hIgG1-Fc tag

CD274 molecule (CD274), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the N-terminal segment (Met 1-Thr 239) of the extracellular domain of human CD274 (NP_054862.1) fused to the Fc region of human IgG1 at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA
. Immobilized human PDCD1/PD1 at 10 µg/ml (100 µg/well) can bind recombinant human CD274/PDL1-Fc chimera with a linear range of 0.02-0.4 µg/ml
.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

CD22 Recombinant Human Protein, His tag

Cluster of Differentiation 22 (CD22), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Arg 687) of human CD22-beta (P20273-1) fused to a polyhistidine tag at the C-terminus.

Activity: This recombinant protein has not been tested.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

PPARA Recombinant Human Protein, Ligand Binding Domain, GST-Tagged

PPARA (peroxisome proliferator activated receptor alpha) ligand binding domain is a 59.40 kDa recombinant human protein (amino acids 192-468) expressed as a GST-tagged fusion protein in baculovirus-infected insect cells. PPAR alpha-LBD was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.

PDCD1 Recombinant Human Protein, hIgG1-Fc.His Tag

Programmed cell death 1 (PDCD1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gln 167) of human PDCD1 (NP_005009.2) fused to the polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA
. Immobilized recombinant human PDCD1LG2 at 1 µg/ml (100 µl/well) can bind human PDCD1-Fc chimera with a linear range of 7.8-1000 ng/ml
.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

Human Estrogen Receptor beta Recombinant Protein (Invitrogen™)

Human Estrogen Receptor beta Recombinant Protein for Western Blot, GS, Ctrl

FCGR3A (CD16a), 176 Phe/Val Recombinant Human Protein, His Tag

Fc gamma receptor III-a (FCGR3A/CD16a), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, studying protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gln 208) of human FCGR3A (P08637-1), containing the mutation 176 Phe/Val, precursor fused to a polyhistidine tag at the C-terminus.

Activity: Measured using the Octet RED System, the affinity constant (Kd) of FCGR3A bound to human IgG1 was 180nM.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.



This protein is manufactured by Sino Biological Inc.

PPARD Recombinant Human Protein, Ligand Binding Domain, GST-Tagged

Peroxisome Proliferator Activated Receptor delta, Ligand Binding Domain (PPAR delta-LBD) is a 59.90 kDa recombinant human protein (amino acids 165-441) expressed as a GST-tagged fusion protein in E. coli cells. PPAR delta-LBD was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.

SOX9 Recombinant Protein (Invitrogen™)

Human SOX9 Recombinant Protein for Ctrl

PDCD1 Recombinant Human Protein, His Tag

Manufactured by Sino Biological (China); Distributed by Life Technologies.

Programmed cell death 1 (PDCD1) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein is expressed from a DNA sequence encoding the extracellular domain (Met 1-Gln 167) of human PDCD1 (NP_005009.2) fused to a polyhistidine tag at the C-terminus.

N-terminal Sequence Analysis: Leu25.

Activity: measured by its binding ability in a functional ELISA . Immobilized human PDCD1 at 10 µg/mL (100 µL/well) has been shown to bind recombinant human CD274-Fc chimera with a linear range of 0.02-0.4 µg/mL.

Formulation: lyophilized in 20 mM Tris, 500 mM NaCl, 500 mM imidazole, pH 7.4, 5% mannitol, 5% trehalose, 0.02% Tween®-80.

Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: expires one year from date of receipt when stored as instructed.

Background
Programmed Cell Death 1 is a type I transmembrane immunoreceptor and belongs to the CD28 immunoglobulin superfamily that mediates immune responses. PD1 is expressed on activated T-cells, B cells, myeloid cells and a subset of thymocytes. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. Furthermore, PD1 is shown to be a regulator of virus-specific CD8+ T cell survival in HIV infection.

You may also be interested in the following PDCD1 products:
Primary Antibodies
Gene Expression Assays

Products related to PDCD1 biological process:

IL-1
IL-4
IL-10

ICAM1 Recombinant Human Protein, hIgG1-Fc.His Tag

Manufactured by Sino Biological (China); Distributed by Life Technologies.

Intercellular adhesion molecule 1 (ICAM1) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in performing cell based assays. It can also be used as a protein standard, or in other research applications.

This recombinant human protein is expressed from a DNA sequence encoding the extracellular domain of human ICAM1 (NP_000192.2) (Met 1 - Glu 480) fused to the polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

N-terminal Sequence Analysis: Gln 28.

Activity: measured by the ability of the immobilized protein to support the adhesion of PMA stimulated HSB2 human peripheral blood acute lymphoblasticleukemia cells. When cells are added to ICAM1 coated plates (12.5 µg/mL, 100 µL/well), approximately 55-65% will adhere specifically.

Formulation: lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% mannitol, 5% trehalose, 0.02% Tween®-80.

Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: expires one year from date of receipt when stored as instructed.

Background
ICAM1 (Inter-Cellular Adhesion Molecule 1), also known as CD54, is a type of intercellular adhesion molecule constitutely present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration.ICAM1 is a ligand for LFA-1(integrin). When activated, leukocytes bind to endothelial cells via ICAM-1 / LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM1 possesses binding sites for a number of immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease.

You may also be interested in the following ICAM1 products:
ELISA Kit
Primary Antibodies
Gene Expression Assays

FXR Human Protein, Ligand Binding Domain, GST-Tagged

Farnesoid X Receptor, Ligand Binding Domain (FXR-LBD) is a 60.07 kDa recombinant human protein (amino acids 193-472) expressed as a GST fusion protein in baculovirus-infected insect cells. FXR-LBD was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.

ER Beta Recombinant Protein, full length

Estrogen receptor (ER) beta is an insect cell-expressed, full-length, untagged, human nuclear hormone receptor that binds estrogens with an affinity similar to that of ER alpha.

ER beta full-length recombinant protein is:

• Flexible—use in your in-house assay or as part of our PolarScreen™ ER Beta Competitive Binding Assay for a complete assay solution
• Ready to use—active, purified, and native (untagged)
• Convenient—available in bulk sizes

ER beta recombinant protein is manufactured under the strictest quality parameters. This product is guaranteed for 6 months after purchase. Contact us for bulk quantities or for assistance with other nuclear receptor assay needs, from assay development to library screening and beyond.

CD38 Recombinant Human Protein, His tag

ADP-Ribosyl Cyclase (CD38), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of human CD38 (NP_001766.2) (Val 43-Ile 300) fused to a C-terminal polyhistidine tag was expressed.

Activity: The activity of this protein has not been tested.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

This protein is manufactured by Sino Biological Inc.

CTLA4 Recombinant Mouse Protein, His Tag

Cytotoxic T-Lymphocyte-Associated 4 (CTLA4), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of mouse CTLA4 (NP_033973.2) (Met 1-Phe 162) fused to a polyhistidine tag at the C-terminus.

Activity: Measured by its binding ability in a functional ELISA.
1. Immobilized recombinant mouse CTLA4-His (Cat:50503-M08H) at 10 µg/ml (100 µl/well) can mouse CD80-Fc (cat:50446-M02H) with a linear range of 0.78-62.5 ng/ml.
2. Immobilized recombinant mouse CTLA4-His (Cat:50503-M08H) at 10 µg/ml (100 µl/well) can human B7-1-Fc (Cat:10698-H03H) with a linear range of 0.78-125 ng/ml..

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

This protein is manufactured by Sino Biological Inc.

PXR (SXR) Ligand Binding Domain Protein

Pregnane X Receptor (Steroid and Xenobiotic Receptor), Ligand Binding Domain (PXR (SXR)-LBD) is a 64.7 kDa recombinant human protein (amino acids 111-434) expressed as a GST fusion protein in baculovirus-infected insect cells. PXR (SXR)-LBD was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator recruitment or displacement studies.