Shop All Cytoplasmic Tyrosine Kinases

TNK2 (ACK) Recominant Human Protein

TNK2 (ACK) (activated Cdc42-associated kinase) is a non-receptor tyrosine kinase that signals downstream of Cdc42. TNK2 is known to be involved in tumorigenesis and metastasis, particularly in prostate cancer.

ABL1 [H396P] Recombinant Human Protein

Human ABL1, internal fragment, amino acids P118-S535 (as in GenBank entry NM_005157.3), H396P mutant, N-terminal GST-HIS6 fusion protein with a 3C cleavage site, expressed in Sf9 insect cells.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

ABL1 [E255K] Recombinant Human Protein

The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The E255K mutant is a Gleevec resistant form of ABL1.

PTK2 (FAK) Recombinant Human Protein

PTK2 (FAK) is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.

TEC Recombinant Human Protein

TEC is a non-receptor protein-tyrosine kinase containing a pleckstrin homology domain and is highly expressed in many hematopoietic cell lines.

TXK Recombinant Human Protein

TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors.

FES (FPS) Recombinant Human Protein

FES (FPS) is a tyrosine protein kinase that is required for maintenance of cellular transformation. Its chromosomal location is linked to a specific translocation event identified in patients with acute promyelocytic leukemia, and it is also involved in normal hematopoiesis.

ABL1 [G250E] Recombinant Human Protein

The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The G250E mutant is a Gleevec resistant form of ABL1.

SYK Recombinant Human Protein

Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases. SYK may also play a role in cancer.

PTK6 (BRK) Recombinant Human Protein

Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines.

ABL1 [M351T] Recombinant Human Protein

Human ABL1, internal fragment, amino acids P118-S535 (as in GenBank entry NM_005157.3), M351T mutant, N-terminal GST-HIS6 fusion protein with a 3C cleavage site, expressed in Sf9 insect cells.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

ABL1 [T315I] Recombinant Human Protein

The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The T315I mutant is a Gleevec resistant form of ABL1.

ABL1 [Q252H] Recombinant Human Protein

Human ABL1, internal fragment, amino acids P118-S535 (as in GenBank entry NM_005157.3), Q252H mutant, N-terminal GST-HIS6 fusion protein with a 3C cleavage site, expressed in Sf9 insect cells.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

FGR Recombinant Human Protein

FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways including within the integrin pathway and downstream of chemokine and cytokine receptors.

SRC N1 Recombinant Human Protein

SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth. SRCN1 is a neuronal splice variant of SRC.