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UltraPure™ 0.5M EDTA, pH 8.0 (Invitrogen™)

UltraPure™ 0.5 M EDTA, pH 8.0 is an aqueous solution prepared by dissolving Na2EDTA•2H2O in distilled, deionized water and adjusting the pH to 8.0 with sodium hydroxide. This sterile-filtered solution is suitable for biochemistry or molecular biology applications requiring a chelator of divalent metal ions.

UltraPure™ Ethylenediaminetetraacetic Acid, Disodium Salt, Dihydrate (Na2EDTA•2H2O) (Invitrogen™)

UltraPure™ Ethylenediaminetetraacetic Acid, Disodium Salt, Dihydrate (Na2EDTA•2H2O), is a chelator of divalent metal cations. It is suitable for biochemistry or molecular biology applications.

Potassium Acetate (3 M), pH 5.5, RNase-free (Invitrogen™)

Ambion® Molecular biology grade, 3 M Potassium Acetate, pH 5.5 solution is supplied in one bottle containing 100 mL. The solution is certified RNase-free, economical, and ready-to-use. Due to the ubiquitous presence of RNases, manufacturing products for use with RNA is especially challenging. Ambion®'s nuclease-free reagents and buffers are manufactured in facilities specifically designed to prevent the introduction of nucleases. Highly sensitive RNase assays are performed at several different stages of the manufacturing process to ensure the highest quality. These reagents are rigorously tested for contaminating nonspecific endonuclease, exonuclease, and RNase activity.

L-Isoleucine, USP/EP/JP (Gibco™)

L-Isoleucine, USP/EP/JP, also known as (2S, 3S)-2-Amino-3-methylpentanoic Acid, is a multi-compendial amino acid for your manufacturing needs and part of our Gibco Chemicals family of products.

Gibco Chemicals is a line of raw materials that fulfill needs throughout the drug development process to commercial production. Standard features include cGMP manufacturing, custom specifications, and a variety of package sizes, as well as a portfolio of cGMP supply chain services to help meet your requirements.

Benefits of Gibco Chemicals include:
Access the materials you need for your R&D and manufacturing processes
Realize manufacturing on a global scale with multi-compendial classifications
Maximize supply chain visibility with transparency of manufacturing and distribution
Eliminate need for re-validation with our comprehensive offering of technical documentation
Streamline supply chain operations by outsourcing key needs such as safety stock storage, custom labeling, and poly-palletization

A focus on quality
Gibco Chemicals are manufactured and distributed through ISO-certified, cGMP-compliant facilities to help meet your regulatory needs and mitigate risk.

Transparency of supply chain
Technical documentation, sales support, and technical service teams are available to provide full visibility into product specifications and journey from manufacturer to your hands.

Custom needs are a standard offering
Gibco Chemicals can be customized to meet your unique specifications including custom fill and weigh requirements, testing protocols, and tailgate samples.

RBS™ 35 Concentrate (Thermo Scientific™)

Thermo Scientific RBS 35 Detergent Concentrate is a general cleaning agent for use on many laboratory surface materials and glassware, including lenses, mirrors, and reflectors.

Applications include the removal of:

• Coomassie blue dye from test tubes and quartz cuvettes
• Blood or serum residue from glass or plastic beakers and flasks
• Colored dyes from porcelain mortar and pestles
• HIV virus from glassware, tabletops and flooring
• Radioactive isotopes from benchtops and instrument surfaces

The cleaning detergent is a mixture of anionic and nonionic surfactants. RBS™ 35 Detergent is strong enough to remove biological residues from plastic and glass, yet it is fully biodegradable and rinses away thoroughly to leave no residue. Use a 2% (v/v) solution for routine washing applications or soaking in a warm 20% solution to free particularly stubborn dry residues. Mix two parts 2% RBS Detergent solution with one part ethyl alcohol to remove greases and oils.

Complete removal of all impurities and contaminants from glassware is a necessity for most laboratory applications. For many years, caustic alcohol and chromic acid solutions were used for many substances that could not be cleaned from glassware by ordinary detergents. These strongly acidic or strongly basic cleaning products reduce the lifespan of glassware while exposing the user to potential harm. By contrast, Thermo Scientific RBS 35 and PCC-54 Products are mildly basic, biodegradable, surfactant concentrates containing anionic and nonionic detergents. The surfactants clean by penetrating between contaminating substances and the surfaces to be cleaned. Glass, plastics, quartz, porcelain and ferrous metal apparatus can be cleaned safely and effectively in a 2% solution (v/v) of the concentrates or a 0.2% solution (w/v) of the solids. RBS 35 and PCC-54 Cleaners remove both organic and inorganic materials and metal ions from laboratory equipment. The detergents rinse away completely, leaving no residue.

Note:
We do not sell RBS Products in Europe; EU customers can purchase our PCC-54 Products instead.

L-Leucine, USP/EP/JP (Gibco™)

L-Leucine, USP/EP/JP, also known as (2S)-2-Amino-4-methylpentanoic Acid, is a multi-compendial amino acid for your manufacturing needs and part of our Gibco Chemicals family of products.

Gibco Chemicals is a line of raw materials that fulfill needs throughout the drug development process to commercial production. Standard features include cGMP manufacturing, custom specifications, and a variety of package sizes, as well as a portfolio of cGMP supply chain services to help meet your requirements.

Benefits of Gibco Chemicals include:
Access the materials you need for your R&D and manufacturing processes
Realize manufacturing on a global scale with multi-compendial classifications
Maximize supply chain visibility with transparency of manufacturing and distribution
Eliminate need for re-validation with our comprehensive offering of technical documentation
Streamline supply chain operations by outsourcing key needs such as safety stock storage, custom labeling, and poly-palletization

A focus on quality
Gibco Chemicals are manufactured and distributed through ISO-certified, cGMP-compliant facilities to help meet your regulatory needs and mitigate risk.

Transparency of supply chain
Technical documentation, sales support, and technical service teams are available to provide full visibility into product specifications and journey from manufacturer to your hands.

Custom needs are a standard offering
Gibco Chemicals can be customized to meet your unique specifications including custom fill and weigh requirements, testing protocols, and tailgate samples.

UltraPure™ Phenol:Water (3.75:1, v/v) (Invitrogen™)

UltraPure™ Phenol:Water (3.75:1, v/v) is used in the purification of nucleic acids. This liquid reagent consists of UltraPure™ Phenol and highly pure deionized water. The reagent can be used to prepare different types of buffer-saturated phenol. When mixtures are extracted with buffer-saturated phenol, proteins are denatured and collect in the organic phase or at the interphase, while nucleic acids remain in the aqueous phase. UltraPure™ Phenol:Water (3.75:1, v/v) contains no preservatives. It is packaged under an inert gas in shatter-resistant, plastic-coated amber bottles.

Performance and Quality Testing: The appearance of the solution is evaluated at room temperature. No RNase or DNase activity detected.

L-Cysteine Hydrochloride-Monohydrate, USP/EP/JP (Gibco™)

L-Cysteine Hydrochloride-Monohydrate, USP/EP/JP, also known as (R)-2-Amino-3-mercaptopropionic Acid Monohydrochloride Monohydrate, is a multi-compendial amino acid for your manufacturing needs and part of our Gibco Chemicals family of products.

Gibco Chemicals is a line of raw materials that fulfill needs throughout the drug development process to commercial production. Standard features include cGMP manufacturing, custom specifications, and a variety of package sizes, as well as a portfolio of cGMP supply chain services to help meet your requirements.

Benefits of Gibco Chemicals include:
Access the materials you need for your R&D and manufacturing processes
Realize manufacturing on a global scale with multi-compendial classifications
Maximize supply chain visibility with transparency of manufacturing and distribution
Eliminate need for re-validation with our comprehensive offering of technical documentation
Streamline supply chain operations by outsourcing key needs such as safety stock storage, custom labeling, and poly-palletization

A focus on quality
Gibco Chemicals are manufactured and distributed through ISO-certified, cGMP-compliant facilities to help meet your regulatory needs and mitigate risk.

Transparency of supply chain
Technical documentation, sales support, and technical service teams are available to provide full visibility into product specifications and journey from manufacturer to your hands.

Custom needs are a standard offering
Gibco Chemicals can be customized to meet your unique specifications including custom fill and weigh requirements, testing protocols, and tailgate samples.

EDTA (0.1 mM), pH 8.0, RNase-free (Invitrogen™)

Ambion® 0.1 mM EDTA is a commonly recommended storage solution for RNA samples. 0.1 mM EDTA is in nuclease-free, ultrapure water. It is provided in one bottle of 50 mL. The last step in every RNA isolation protocol is to resuspend the purified RNA pellet. After painstakingly isolating the RNA, it is crucial that the pellet be suspended and stored in a safe, RNase-free solution. 0.1 mM EDTA is prepared from the purest reagents available, under scrupulously monitored conditions in a state-of-the-art manufacturing facility. It is then subjected to rigorous quality control procedures to guarantee their purity and performance.

UltraPure™ Glycine (Invitrogen™)

UltraPure™ Glycine is an amino acid used in the preparation of some electrophoresis buffers. With a pKa1 of 2.3 and a pKa2 of 9.6, UltraPure™ Glycine is suitable for buffering at the extremes of the common buffering range.

L-Tryptophan, USP/EP/JP (Gibco™)

L-Tryptophan, USP/EP/JP, also known as (2S)-2-Amino-3-(indol-3-yl) Propanoic Acid, is a multi-compendial amino acid for your manufacturing needs and part of our Gibco Chemicals family of products.

Gibco Chemicals is a line of raw materials that fulfill needs throughout the drug development process to commercial production. Standard features include cGMP manufacturing, custom specifications, and a variety of package sizes, as well as a portfolio of cGMP supply chain services to help meet your requirements.

Benefits of Gibco Chemicals include:
Access the materials you need for your R&D and manufacturing processes
Realize manufacturing on a global scale with multi-compendial classifications
Maximize supply chain visibility with transparency of manufacturing and distribution
Eliminate need for re-validation with our comprehensive offering of technical documentation
Streamline supply chain operations by outsourcing key needs such as safety stock storage, custom labeling, and poly-palletization

A focus on quality
Gibco Chemicals are manufactured and distributed through ISO-certified, cGMP-compliant facilities to help meet your regulatory needs and mitigate risk.

Transparency of supply chain
Technical documentation, sales support, and technical service teams are available to provide full visibility into product specifications and journey from manufacturer to your hands.

Custom needs are a standard offering
Gibco Chemicals can be customized to meet your unique specifications including custom fill and weigh requirements, testing protocols, and tailgate samples.

5-Fluoroorotic Acid (Thermo Scientific™)

Thermo Scientific 5-Fluoroorotic Acid (5-fluorouracil-6-carboxylic acid monohydrate; 5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase. Yeasts with an active URA3 gene (Ura+) convert 5-FOA to fluorodeoxyuridine, which is toxic to cells (see the scheme below). Yeast strains carrying a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil. 5-FOA is frequently used in experiments with Saccharomyces cerevisiae (URA3), Schizosaccharomyces pombe (URA4 and URA5), Candida albicans (URA3), and E. coli (pyrF).

Applications

• Detection of URA3 gene expression in yeast
• Construction of yeast 2-hybrid libraries
• Other areas of yeast genetics including gene replacement, analysis of transposable genetic elements, and identification of gene mutation

Note
• Low solubility in water
• Solubility in dimethylsulfoxide is greater than 150 mg/mL
• Preparation of a 100 mg/mL solution in dimethylsulfoxide is recommended

KCl (2 M), RNase-free (Invitrogen™)

Ambion® Molecular biology grade, 2 M KCl solution is supplied in one bottle containing 100 mL. The solution is certified RNase-free, economical, and ready-to-use. Due to the ubiquitous presence of RNases, manufacturing products for use with RNA is especially challenging. Ambion®'s nuclease-free reagents and buffers are manufactured in facilities specifically designed to prevent the introduction of nucleases. Highly sensitive RNase assays are performed at several different stages of the manufacturing process to ensure the highest quality. These reagents are rigorously tested for contaminating nonspecific endonuclease, exonuclease, and RNase activity.

L-Threonine, USP/EP/JP (Gibco™)

L-Threonine, USP/EP/JP, also known as (2S,3R)-2-Amino-3-hydroxybutanoic Acid, is a multi-compendial amino acid for your manufacturing needs and part of our Gibco Chemicals family of products.

Gibco Chemicals is a line of raw materials that fulfill needs throughout the drug development process to commercial production. Standard features include cGMP manufacturing, custom specifications, and a variety of package sizes, as well as a portfolio of cGMP supply chain services to help meet your requirements.

Benefits of Gibco Chemicals include:
Access the materials you need for your R&D and manufacturing processes
Realize manufacturing on a global scale with multi-compendial classifications
Maximize supply chain visibility with transparency of manufacturing and distribution
Eliminate need for re-validation with our comprehensive offering of technical documentation
Streamline supply chain operations by outsourcing key needs such as safety stock storage, custom labeling, and poly-palletization

A focus on quality
Gibco Chemicals are manufactured and distributed through ISO-certified, cGMP-compliant facilities to help meet your regulatory needs and mitigate risk.

Transparency of supply chain
Technical documentation, sales support, and technical service teams are available to provide full visibility into product specifications and journey from manufacturer to your hands.

Custom needs are a standard offering
Gibco Chemicals can be customized to meet your unique specifications including custom fill and weigh requirements, testing protocols, and tailgate samples.

L-Valine, USP/EP/JP (Gibco™)

L-Valine, USP/EP/JP, also known as (2S)-2-Amino-3-Methylbutanoic Acid, is a multi-compendial amino acid for your manufacturing needs and part of our Gibco Chemicals family of products.

Gibco Chemicals is a line of raw materials that fulfill needs throughout the drug development process to commercial production. Standard features include cGMP manufacturing, custom specifications, and a variety of package sizes, as well as a portfolio of cGMP supply chain services to help meet your requirements.

Benefits of Gibco Chemicals include:
Access the materials you need for your R&D and manufacturing processes
Realize manufacturing on a global scale with multi-compendial classifications
Maximize supply chain visibility with transparency of manufacturing and distribution
Eliminate need for re-validation with our comprehensive offering of technical documentation
Streamline supply chain operations by outsourcing key needs such as safety stock storage, custom labeling, and poly-palletization

A focus on quality
Gibco Chemicals are manufactured and distributed through ISO-certified, cGMP-compliant facilities to help meet your regulatory needs and mitigate risk.

Transparency of supply chain
Technical documentation, sales support, and technical service teams are available to provide full visibility into product specifications and journey from manufacturer to your hands.

Custom needs are a standard offering
Gibco Chemicals can be customized to meet your unique specifications including custom fill and weigh requirements, testing protocols, and tailgate samples.