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Vector NTI™ Express Designer Custom Services (Invitrogen™)

This is a custom services engagement offered on a per hour basis for Vector NTI® Express Designer.

Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use with a broad range of assembly techniques and hosts.

Compared to traditional sequence analysis and design, Vector NTI® Express Designer allows you to:

• Construct custom vectors faster
• Build complex constructs (circuits) more easily
• Perform sequence optimization & dispatch DNA synthesis services more efficiently
• Generate variants from template DNA parts, devices, and circuits more effectively

Rational Bio-design
Vector NTI® Express Designer enables reliable reuse of parts in the context of a family of validated parts.Simply begin with the end in mind and work back from the desired results:

• Use existing parts (validated & non-validated from public and private parts repositories)
• Design new parts from any DNA sequence
• Characterize parts (use experimental techniques to profile part performance in a range of contexts)
• Build a "device" from one or more parts, and build a "circuit" from one or more devices
• Create relationships between parts, devices, and circuits (e.g., have one part/device/circuit activate or repress another)
• Manage your parts, devices, and circuits in the Database Explorer and Designer modules

This new, rational design methodology facilitates your ability to manage complex, multi-gene to multi-protein experimental designs, to visualize interactions within your host systems, and to optimize those designs informed by experimental results. This approach enables reuse of validated designs for further experimentation and more efficient improvement of challenging designs.

Real World Applications (Bio-design Workflows):
Experimental design: development, validation, refactoring, and reuse of new and existing genetic components and associated assays as part of a study design and validation process
Next gen cloning & assembly: comparison of multiple cloning and assembly approaches in silico for identification of optimal approaches to assemble clones and identification of experimental issues before performing experiments at the bench
Gene optimization & synthesis: use best practices in sequence optimization and gene synthesis to optimize expression
Bioinformatics: integration of sequence design and analysis tools empowers users to easily translate biological knowledge into experimental design

Additional Applications:
Vector NTI® Express Designer is built on a the Vector NTI® Sequence Analysis and Design platform, and so inherits many of the applications associated with that platform, including: sequence analysis and design, annotation, and illustration; molecular biology data management; open reading frame and restriction enzyme analysis and mapping; primer design; recombinant molecule design, including Gateway® and TOPO® cloning; and GeneArt® seamless cloning & high-order assembly and in silico gene synthesis.

Built on trusted Vector NTI® tools, Vector NTI® Express Designer enables rational bio-design on the most popular computing architectures, including native Mac OSX 10.6+, Windows XP, and Windows 7 operating systems. Plug-in architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time. And automatic updating ensures that users will be automatically notified of updates and given the option to download new or updated plug-ins, so that they will always be running the latest, most complete software package available.

Vector NTI™ Express Designer Academic License, Static (Invitrogen™)

This is a static, non-expiring license for Vector NTI® Express Designer that is intended for academic users. For maximum benefit of this license, we recommend purchase of an Advanced Support Agreement (A15316).

Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use with a broad range of assembly techniques and hosts.

Compared to traditional sequence analysis and design, Vector NTI® Express Designer allows you to:

• Construct custom vectors faster
• Build complex constructs (circuits) more easily
• Perform sequence optimization & dispatch DNA synthesis services more efficiently
• Generate variants from template DNA parts, devices, and circuits more effectively

Rational Bio-design
Vector NTI® Express Designer enables reliable reuse of parts in the context of a family of validated parts.Simply begin with the end in mind and work back from the desired results:

• Use existing parts (validated & non-validated from public and private parts repositories)
• Design new parts from any DNA sequence
• Characterize parts (use experimental techniques to profile part performance in a range of contexts)
• Build a "device" from one or more parts, and build a "circuit" from one or more devices
• Create relationships between parts, devices, and circuits (e.g., have one part/device/circuit activate or repress another)
• Manage your parts, devices, and circuits in the Database Explorer and Designer modules

This new, rational design methodology facilitates your ability to manage complex, multi-gene to multi-protein experimental designs, to visualize interactions within your host systems, and to optimize those designs informed by experimental results. This approach enables reuse of validated designs for further experimentation and more efficient improvement of challenging designs.

Real World Applications (Bio-design Workflows):
Experimental design: development, validation, refactoring, and reuse of new and existing genetic components and associated assays as part of a study design and validation process
Next gen cloning & assembly: comparison of multiple cloning and assembly approaches in silico for identification of optimal approaches to assemble clones and identification of experimental issues before performing experiments at the bench
Gene optimization & synthesis: use best practices in sequence optimization and gene synthesis to optimize expression
Bioinformatics: integration of sequence design and analysis tools empowers users to easily translate biological knowledge into experimental design

Additional Applications:
Vector NTI® Express Designer is built on a the Vector NTI® Sequence Analysis and Design platform, and so inherits many of the applications associated with that platform, including: sequence analysis and design, annotation, and illustration; molecular biology data management; open reading frame and restriction enzyme analysis and mapping; primer design; recombinant molecule design, including Gateway® and TOPO® cloning; and GeneArt® seamless cloning & high-order assembly and in silico gene synthesis.

Built on trusted Vector NTI® tools, Vector NTI® Express Designer enables rational bio-design on the most popular computing architectures, including native Mac OSX 10.6+, Windows XP, and Windows 7 operating systems. Plug-in architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time. And automatic updating ensures that users will be automatically notified of updates and given the option to download new or updated plug-ins, so that they will always be running the latest, most complete software package available.

Vector NTI™ Express Designer Industrial License, 1 year (Invitrogen™)

This is a 1-year license for Vector NTI® Express Designer that is intended for industrial users.

Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use with a broad range of assembly techniques and hosts.

Compared to traditional sequence analysis and design, Vector NTI® Express Designer allows you to:

• Construct custom vectors faster
• Build complex constructs (circuits) more easily
• Perform sequence optimization & dispatch DNA synthesis services more efficiently
• Generate variants from template DNA parts, devices, and circuits more effectively

Rational Bio-design
Vector NTI® Express Designer enables reliable reuse of parts in the context of a family of validated parts.Simply begin with the end in mind and work back from the desired results:

• Use existing parts (validated & non-validated from public and private parts repositories)
• Design new parts from any DNA sequence
• Characterize parts (use experimental techniques to profile part performance in a range of contexts)
• Build a "device" from one or more parts, and build a "circuit" from one or more devices
• Create relationships between parts, devices, and circuits (e.g., have one part/device/circuit activate or repress another)
• Manage your parts, devices, and circuits in the Database Explorer and Designer modules

This new, rational design methodology facilitates your ability to manage complex, multi-gene to multi-protein experimental designs, to visualize interactions within your host systems, and to optimize those designs informed by experimental results. This approach enables reuse of validated designs for further experimentation and more efficient improvement of challenging designs.

Real World Applications (Bio-design Workflows):
Experimental design: development, validation, refactoring, and reuse of new and existing genetic components and associated assays as part of a study design and validation process
Next gen cloning & assembly: comparison of multiple cloning and assembly approaches in silico for identification of optimal approaches to assemble clones and identification of experimental issues before performing experiments at the bench
Gene optimization & synthesis: use best practices in sequence optimization and gene synthesis to optimize expression
Bioinformatics: integration of sequence design and analysis tools empowers users to easily translate biological knowledge into experimental design

Additional Applications:
Vector NTI® Express Designer is built on a the Vector NTI® Sequence Analysis and Design platform, and so inherits many of the applications associated with that platform, including: sequence analysis and design, annotation, and illustration; molecular biology data management; open reading frame and restriction enzyme analysis and mapping; primer design; recombinant molecule design, including Gateway® and TOPO® cloning; and GeneArt® seamless cloning & high-order assembly and in silico gene synthesis.

Built on trusted Vector NTI® tools, Vector NTI® Express Designer enables rational bio-design on the most popular computing architectures, including native Mac OSX 10.6+, Windows XP, and Windows 7 operating systems. Plug-in architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time. And automatic updating ensures that users will be automatically notified of updates and given the option to download new or updated plug-ins, so that they will always be running the latest, most complete software package available.

Vector NTI™ Express Static Academic License (Invitrogen™)

Vector NTI® Express Sequence Analysis & Design Software is all new for 2012, and is completely redesigned for speed, ease of use, and simplicity; while retaining the trusted tools in Vector NTI Advance® software. Vector NTI® Express is built on a new platform that is designed to support the future of Bioinformatics. It supports the rapidly developing disciples of Next Generation Sequencing and Synthetic Biology on the most popular computing architectures, including native Mac OSX 10.6+, Windows® 7, and Windows® XP operating systems.

This is a non-expiring license for use in academic and government research. This license includes basic support and minor upgrades as needed during the license term. An additional annual software maintenance and support option (Advanced Support) is available to provide unlimited license replacements or re-installations, phone and email support, and major upgrades during the term of support.

What’s New in Vector NTI® Express:

Next Generation Sequencing (NGS) Support, including support for BAM files (e.g., Ion Torrent PGM™, SOLiD®, and Illumina® HiSeq® platforms). Note: a 3rd Party BAM file parser is required to save files in FASTA format, which Vector NTI® Express can then read. (We recommend SAM Tools, Piccard).
Tools for Studying DNA-Protein Relationships, including translation, reverse-translation, and codon optimization.
Prescribed, Step-by-Step Workflow to simplify complex tasks, such as contig assembly, multiple sequence alignment, and cloning.
EMBOSS Algorithms: Standards-Based Bioinformatics algorithms (the same as Vector NTI Advance® software, and now using a standard, well documented software library), import support for analysis file types (BED, GFF, GTF), Compare Annotation on a Genome–Multi-Track Analysis (Gene, Promoter, Multiple Splice Variants, Transcript, Protein, and Terminator), and intersections to create new annotations.
Plug-in Architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time.
Automatic Updates: When a user starts the Vector NTI® Express software, they will automatically be notified of updates and given the option to download the new or updated plug-ins. This will ensure that all users are running the latest, most complete software package available.

Standard Bioinformatics Toolbox empowers you to:
Curate: Visualize, search, store, organize, manage sequences
Discover: Search, analyze, compare & contrast sequences
Design: Cloning, primer design, gel simulation
Confirm: Contig assembly, seq validation, literature validation

Integrated Workflows deliver powerful results with rich visualizations for publications.

Common applications include:

• Sequence analysis, annotation, and illustration
• Molecular biology data management
• Restriction mapping
• Primer design
• Recombinant molecule design, including Gateway® and TOPO® cloning
• GeneArt® seamless cloning & high-order assembly and in silico gene synthesis

Vector NTI™ Express Dynamic Advanced Support (Invitrogen™)

The Advanced Support option for Vector NTI® Express gives you added assurance that problems or concerns that may arise during the use of Vector NTI® Express will be addressed promptly in order to minimize interruption to your research.

This support plan is for the Vector NTI® Express Dynamic License, which gives a single user access to Vector NTI® Express on a workstation for which there is also a Seat License.

The Advanced Support option gives you:
• Unlimited license replacement and re-installation
• Phone and email support
• Access to major upgrades

About Vector NTI® Express
Vector NTI® Express Sequence Analysis & Design Software is all new for 2012, and is completely redesigned for speed, ease of use, and simplicity; while retaining the trusted tools in Vector NTI Advance® software. Vector NTI® Express is built on a new platform that is designed to support the future of bioinformatics. It supports the rapidly developing disciplines of Next Generation Sequencing and Synthetic Biology on the most popular computing architectures, including: native Mac OSX 10.6+, Windows® 7, and Windows® XP operating systems.

Vector NTI™ Express Workgroup Advanced Support (Invitrogen™)

The Advanced Support option for Vector NTI® Express gives you added assurance that problems or concerns that may arise during the use of Vector NTI® Express will be addressed promptly in order to minimize interruption to your research.

This support plan is for a Vector NTI® Express Workgroup License (5).

The Advanced Support option gives you:
• Unlimited license replacement and re-installation
• Phone and email support
• Access to major upgrades

About Vector NTI® Express
Vector NTI® Express Sequence Analysis & Design Software is all new for 2012, and is completely redesigned for speed, ease of use, and simplicity; while retaining the trusted tools in Vector NTI Advance® software. Vector NTI® Express is built on a new platform that is designed to support the future of bioinformatics. It supports the rapidly developing disciplines of Next Generation Sequencing and Synthetic Biology on the most popular computing architectures, including: native Mac OSX 10.6+, Windows® 7, and Windows® XP operating systems.

Vector NTI™ Express Static License Upgrade (Invitrogen™)

This is an upgrade to a Vector NTI® Express Static License. A Static license includes basic support and minor upgrades as needed during the license term. An additional annual software maintenance and support option (Advanced Support) is available to provide unlimited license replacements or re-installations, phone and email support, and major upgrades during the term of support.

This upgrade may be applied to Vector NTI® Express software used in academic, government, or industrial research.

About Vector NTI® Express
Vector NTI® Express Sequence Analysis & Design Software is all new for 2012, and is completely redesigned for speed, ease of use, and simplicity; while retaining the trusted tools in Vector NTI Advance® software. Vector NTI® Express is built on a new platform that is designed to support the future of bioinformatics. It supports the rapidly developing disciplines of Next Generation Sequencing and Synthetic Biology on the most popular computing architectures, including: native Mac OSX 10.6+, Windows® 7, and Windows® XP operating systems.

Vector NTI™ Express Workgroup License (Invitrogen™)

Vector NTI® Express Sequence Analysis & Design Software is all new for 2012, and is completely redesigned for speed, ease of use, and simplicity; while retaining the trusted tools in Vector NTI Advance® software. Vector NTI® Express is built on a new platform that is designed to support the future of bioinformatics. It supports the rapidly developing disciplines of Next Generation Sequencing and Synthetic Biology on the most popular computing architectures, including: native Mac OSX 10.6+, Windows® 7, and Windows® XP operating systems.

This non-expiring Workgroup License allows users on 5 separate computers to share sequence data and bioinformatics work. Each computer must have Vector NTI® Express software installed and activated in order to participate in a Workgroup License. Advanced Support is also required for Workgroup Licenses.

This license is available for academic, government, and industrial research.

What's New in Vector NTI® Express:

Next Generation Sequencing (NGS) Support, including support for BAM files (e.g., Ion Torrent PGM™, SOLiD®, and Illumina® HiSeq® platforms). Note: a 3rd Party BAM file parser is required to save files in FASTA format, which Vector NTI® Express can then read. (We recommend SAM Tools, Piccard.)
Tools for Studying DNA-Protein Relationships, including translation, reverse-translation, and codon optimization
Prescribed, Step-by-Step Workflow to simplify complex tasks, such as contig assembly, multiple sequence alignment, and cloning
EMBOSS Algorithms: Standards-Based Bioinformatics algorithms (the same as Vector NTI Advance® software, and now using a standard, well documented software library), import support for analysis file types (BED, GFF, GTF), Compare Annotation on a Genome-Multi-Track Analysis (Gene, Promoter, Multiple Splice Variants, Transcript, Protein, and Terminator), and intersections to create new annotations
Plug-in Architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time
Automatic Updates: When a user starts the Vector NTI® Express software, they will automatically be notified of updates and given the option to download the new or updated plug-ins. This will ensure that all users are running the latest, most complete software package available.

Standard Bioinformatics Toolbox empowers you to:
Curate: Visualize, search, store, organize, manage sequences
Discover: Search, analyze, compare & contrast sequences
Design: Cloning, primer design, gel simulation
Confirm: Contig assembly, seq validation, literature validation

Integrated Workflows deliver powerful results with rich visualizations for publications.

Common applications include:

• Sequence analysis, annotation, and illustration
• Molecular biology data management
• Restriction mapping
• Primer design
• Recombinant molecule design, including Gateway® and TOPO® cloning
• GeneArt® seamless cloning & high-order assembly and in silico gene synthesis

Vector NTI™ Express Designer Dynamic License (Invitrogen™)

This is a dynamic license for Vector NTI® Express Designer that requires seat license(s) (A15322) and an annual Advanced Support Agreement (A15320). A set of dynamic licenses represents the total number of users that can actively use the software at any one time, as opposed to seat licenses which are purchased for each individual user of the software.

Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use with a broad range of assembly techniques and hosts.

Compared to traditional sequence analysis and design, Vector NTI® Express Designer allows you to:

• Construct custom vectors faster
• Build complex constructs (circuits) more easily
• Perform sequence optimization & dispatch DNA synthesis services more efficiently
• Generate variants from template DNA parts, devices, and circuits more effectively

Rational Bio-design
Vector NTI® Express Designer enables reliable reuse of parts in the context of a family of validated parts.Simply begin with the end in mind and work back from the desired results:

• Use existing parts (validated & non-validated from public and private parts repositories)
• Design new parts from any DNA sequence
• Characterize parts (use experimental techniques to profile part performance in a range of contexts)
• Build a "device" from one or more parts, and build a "circuit" from one or more devices
• Create relationships between parts, devices, and circuits (e.g., have one part/device/circuit activate or repress another)
• Manage your parts, devices, and circuits in the Database Explorer and Designer modules

This new, rational design methodology facilitates your ability to manage complex, multi-gene to multi-protein experimental designs, to visualize interactions within your host systems, and to optimize those designs informed by experimental results. This approach enables reuse of validated designs for further experimentation and more efficient improvement of challenging designs.

Real World Applications (Bio-design Workflows):
Experimental design: development, validation, refactoring, and reuse of new and existing genetic components and associated assays as part of a study design and validation process
Next gen cloning & assembly: comparison of multiple cloning and assembly approaches in silico for identification of optimal approaches to assemble clones and identification of experimental issues before performing experiments at the bench
Gene optimization & synthesis: use best practices in sequence optimization and gene synthesis to optimize expression
Bioinformatics: integration of sequence design and analysis tools empowers users to easily translate biological knowledge into experimental design

Additional Applications:
Vector NTI® Express Designer is built on a the Vector NTI® Sequence Analysis and Design platform, and so inherits many of the applications associated with that platform, including: sequence analysis and design, annotation, and illustration; molecular biology data management; open reading frame and restriction enzyme analysis and mapping; primer design; recombinant molecule design, including Gateway® and TOPO® cloning; and GeneArt® seamless cloning & high-order assembly and in silico gene synthesis.

Built on trusted Vector NTI® tools, Vector NTI® Express Designer enables rational bio-design on the most popular computing architectures, including native Mac OSX 10.6+, Windows XP, and Windows 7 operating systems. Plug-in architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time. And automatic updating ensures that users will be automatically notified of updates and given the option to download new or updated plug-ins, so that they will always be running the latest, most complete software package available.

Vector NTI Advance™ Workgroup (PC), 6-10 users (Invitrogen™)

Special databases, repositories of DNA⁄RNA or protein molecules, enzymes, oligonucleotides, and gel markers, can be created and shared between several Vector NTI users on a network.

Shared databases are not a replacement for local databases; each Vector NTI application still must have its own local database. The local database is used in all operations: construction, design, creation of viewers etc. The local database is also the place for storing private and temporary data.

The main purpose of the shared database is to store common data. The only operations you can perform on shared databases are:

1. Copying data to⁄from the local database.
2. Various database management operations such as creating and deleting subsets, etc.
3. Database searches.

For instance, you may copy some of your molecules and enzymes from your local database into the shared database. In order to use them in the design process, your colleague must copy them to his⁄her local database first. In addition to biological data, each database contains information about its creator and registered users. Only the creator and registered users can have access to database data. The database creator can also change database properties, remove registered users, and define the password required to become a register user.

Note: Vector NTI shared databases use portable data format and file naming conventions to ensure that both Macintosh and Windows users of Vector NTI can access common databases. Shared databases can be located on a wide range of file servers—Vector NTI can work using not only services native to each system, (Microsoft Network or AppleTalk) but also various Unix (NFS or Samba) and NetWare services.

Vector NTI™ Express Designer Industrial License, Static (Invitrogen™)

This is a static, non-expiring license for Vector NTI® Express Designer that is intended for industrial users. For maximum benefit of this license, we recommend purchase of an Advanced Support Agreement (A15316).

Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use with a broad range of assembly techniques and hosts.

Compared to traditional sequence analysis and design, Vector NTI® Express Designer allows you to:

• Construct custom vectors faster
• Build complex constructs (circuits) more easily
• Perform sequence optimization & dispatch DNA synthesis services more efficiently
• Generate variants from template DNA parts, devices, and circuits more effectively

Rational Bio-design
Vector NTI® Express Designer enables reliable reuse of parts in the context of a family of validated parts.Simply begin with the end in mind and work back from the desired results:

• Use existing parts (validated & non-validated from public and private parts repositories)
• Design new parts from any DNA sequence
• Characterize parts (use experimental techniques to profile part performance in a range of contexts)
• Build a "device" from one or more parts, and build a "circuit" from one or more devices
• Create relationships between parts, devices, and circuits (e.g., have one part/device/circuit activate or repress another)
• Manage your parts, devices, and circuits in the Database Explorer and Designer modules

This new, rational design methodology facilitates your ability to manage complex, multi-gene to multi-protein experimental designs, to visualize interactions within your host systems, and to optimize those designs informed by experimental results. This approach enables reuse of validated designs for further experimentation and more efficient improvement of challenging designs.

Real World Applications (Bio-design Workflows):
Experimental design: development, validation, refactoring, and reuse of new and existing genetic components and associated assays as part of a study design and validation process
Next gen cloning & assembly: comparison of multiple cloning and assembly approaches in silico for identification of optimal approaches to assemble clones and identification of experimental issues before performing experiments at the bench
Gene optimization & synthesis: use best practices in sequence optimization and gene synthesis to optimize expression
Bioinformatics: integration of sequence design and analysis tools empowers users to easily translate biological knowledge into experimental design

Additional Applications:
Vector NTI® Express Designer is built on a the Vector NTI® Sequence Analysis and Design platform, and so inherits many of the applications associated with that platform, including: sequence analysis and design, annotation, and illustration; molecular biology data management; open reading frame and restriction enzyme analysis and mapping; primer design; recombinant molecule design, including Gateway® and TOPO® cloning; and GeneArt® seamless cloning & high-order assembly and in silico gene synthesis.

Built on trusted Vector NTI® tools, Vector NTI® Express Designer enables rational bio-design on the most popular computing architectures, including native Mac OSX 10.6+, Windows XP, and Windows 7 operating systems. Plug-in architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time. And automatic updating ensures that users will be automatically notified of updates and given the option to download new or updated plug-ins, so that they will always be running the latest, most complete software package available.

Vector NTI™ Express 1-Yr. Term Industrial License (Invitrogen™)

Vector NTI® Express Sequence Analysis & Design Software is all new for 2012, and is completely redesigned for speed, ease of use, and simplicity; while retaining the trusted tools in Vector NTI Advance® software. Vector NTI® Express is built on a new platform that is designed to support the future of Bioinformatics. It supports the rapidly developing disciples of Next Generation Sequencing and Synthetic Biology on the most popular computing architectures, including native Mac OSX 10.6+, Windows® 7, and Windows® XP operating systems.

This is a 1-year term license for use in industrial research. This license includes basic support and minor upgrades as needed during the license term. After expiration, a new license can be purchased.

What’s New in Vector NTI® Express:

Next Generation Sequencing (NGS) Support, including support for BAM files (e.g., Ion Torrent PGM™, SOLiD®, and Illumina® HiSeq® platforms). Note: a 3rd Party BAM file parser is required to save files in FASTA format, which Vector NTI® Express can then read. (We recommend SAM Tools, Piccard)
Tools for Studying DNA-Protein Relationships, including translation, reverse-translation, and codon optimization.
Prescribed, Step-by-Step Workflow to simplify complex tasks, such as contig assembly, multiple sequence alignment, and cloning.
EMBOSS Algorithms: Standards-Based Bioinformatics algorithms (the same as Vector NTI Advance® software, and now using a standard, well documented software library), import support for analysis file types (BED, GFF, GTF), Compare Annotation on a Genome–Multi-Track Analysis (Gene, Promoter, Multiple Splice Variants, Transcript, Protein, and Terminator), and intersections to create new annotations.
Plug-in Architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time.
Automatic Updates: When a user starts the Vector NTI® Express software, they will automatically be notified of updates and given the option to download the new or updated plug-ins. This will ensure that all users are running the latest, most complete software package available.

Standard Bioinformatics Toolbox empowers you to:
Curate: Visualize, search, store, organize, manage sequences
Discover: Search, analyze, compare & contrast sequences
Design: Cloning, primer design, gel simulation
Confirm: Contig assembly, seq validation, literature validation

Integrated Workflows deliver powerful results with rich visualizations for publications.

Common applications include:

• Sequence analysis, annotation, and illustration
• Molecular biology data management
• Restriction mapping
• Primer design
• Recombinant molecule design, including Gateway® and TOPO® cloning
• GeneArt® seamless cloning & high-order assembly and in silico gene synthesis

Vector NTI Advance™ Sequence Analysis Software Network License (Invitrogen™)

The price shown is the list price. To inquire on volume discount or account-specific pricing, please email bioinfosales@invitrogen.com or visit the Vector NTI® Software page.

Network Licenses are based on the concept of sharing a license among networked computers. All the networked computers (known as “Access Seats") are connected to a designated machine running Invitrogen’s Dynamic License Server (DLS) software. Network Licenses are useful for large groups of users who wish to maximize the number of individual computers that can run a copy of the Vector application.

Vector NTI™ Express Designer Seat License (Invitrogen™)

This is a seat license for Vector NTI® Express Designer that requires dynamic license(s) (A15319) and an annual Advanced Support Agreement (A15323). Seat licenses are purchased for each individual user of the software, as opposed to a set of dynamic licenses which represents the number of users that can actively use the software at any one time.

Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use with a broad range of assembly techniques and hosts.

Compared to traditional sequence analysis and design, Vector NTI® Express Designer allows you to:

• Construct custom vectors faster
• Build complex constructs (circuits) more easily
• Perform sequence optimization & dispatch DNA synthesis services more efficiently
• Generate variants from template DNA parts, devices, and circuits more effectively

Rational Bio-design
Vector NTI® Express Designer enables reliable reuse of parts in the context of a family of validated parts.Simply begin with the end in mind and work back from the desired results:

• Use existing parts (validated & non-validated from public and private parts repositories)
• Design new parts from any DNA sequence
• Characterize parts (use experimental techniques to profile part performance in a range of contexts)
• Build a "device" from one or more parts, and build a "circuit" from one or more devices
• Create relationships between parts, devices, and circuits (e.g., have one part/device/circuit activate or repress another)
• Manage your parts, devices, and circuits in the Database Explorer and Designer modules

This new, rational design methodology facilitates your ability to manage complex, multi-gene to multi-protein experimental designs, to visualize interactions within your host systems, and to optimize those designs informed by experimental results. This approach enables reuse of validated designs for further experimentation and more efficient improvement of challenging designs.

Real World Applications (Bio-design Workflows):
Experimental design: development, validation, refactoring, and reuse of new and existing genetic components and associated assays as part of a study design and validation process
Next gen cloning & assembly: comparison of multiple cloning and assembly approaches in silico for identification of optimal approaches to assemble clones and identification of experimental issues before performing experiments at the bench
Gene optimization & synthesis: use best practices in sequence optimization and gene synthesis to optimize expression
Bioinformatics: integration of sequence design and analysis tools empowers users to easily translate biological knowledge into experimental design

Additional Applications:
Vector NTI® Express Designer is built on a the Vector NTI® Sequence Analysis and Design platform, and so inherits many of the applications associated with that platform, including: sequence analysis and design, annotation, and illustration; molecular biology data management; open reading frame and restriction enzyme analysis and mapping; primer design; recombinant molecule design, including Gateway® and TOPO® cloning; and GeneArt® seamless cloning & high-order assembly and in silico gene synthesis.

Built on trusted Vector NTI® tools, Vector NTI® Express Designer enables rational bio-design on the most popular computing architectures, including native Mac OSX 10.6+, Windows XP, and Windows 7 operating systems. Plug-in architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time. And automatic updating ensures that users will be automatically notified of updates and given the option to download new or updated plug-ins, so that they will always be running the latest, most complete software package available.

Vector NTI™ Express Designer Advanced Support Agreement for Workgroup License (Invitrogen™)

This is a 1-year Advanced Support Agreement for a workgroup license serving up to 50 users of Vector NTI® Express Designer. Our Advanced Support Agreement includes unlimited license support (e.g., re-registration or transfer of a license), telephone and e-mail technical support, and access to all updates and upgrades during the period of the agreement. Without an Advanced Support Agreement you will receive one courtesy license support engagement, e-mail-only technical support, and no updates or upgrades (upgrade licenses can be purchased separately as needed).

Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use with a broad range of assembly techniques and hosts.

Compared to traditional sequence analysis and design, Vector NTI® Express Designer allows you to:

• Construct custom vectors faster
• Build complex constructs (circuits) more easily
• Perform sequence optimization & dispatch DNA synthesis services more efficiently
• Generate variants from template DNA parts, devices, and circuits more effectively

Rational Bio-design
Vector NTI® Express Designer enables reliable reuse of parts in the context of a family of validated parts.Simply begin with the end in mind and work back from the desired results:

• Use existing parts (validated & non-validated from public and private parts repositories)
• Design new parts from any DNA sequence
• Characterize parts (use experimental techniques to profile part performance in a range of contexts)
• Build a "device" from one or more parts, and build a "circuit" from one or more devices
• Create relationships between parts, devices, and circuits (e.g., have one part/device/circuit activate or repress another)
• Manage your parts, devices, and circuits in the Database Explorer and Designer modules

This new, rational design methodology facilitates your ability to manage complex, multi-gene to multi-protein experimental designs, to visualize interactions within your host systems, and to optimize those designs informed by experimental results. This approach enables reuse of validated designs for further experimentation and more efficient improvement of challenging designs.

Real World Applications (Bio-design Workflows):
Experimental design: development, validation, refactoring, and reuse of new and existing genetic components and associated assays as part of a study design and validation process
Next gen cloning & assembly: comparison of multiple cloning and assembly approaches in silico for identification of optimal approaches to assemble clones and identification of experimental issues before performing experiments at the bench
Gene optimization & synthesis: use best practices in sequence optimization and gene synthesis to optimize expression
Bioinformatics: integration of sequence design and analysis tools empowers users to easily translate biological knowledge into experimental design

Additional Applications:
Vector NTI® Express Designer is built on a the Vector NTI® Sequence Analysis and Design platform, and so inherits many of the applications associated with that platform, including: sequence analysis and design, annotation, and illustration; molecular biology data management; open reading frame and restriction enzyme analysis and mapping; primer design; recombinant molecule design, including Gateway® and TOPO® cloning; and GeneArt® seamless cloning & high-order assembly and in silico gene synthesis.

Built on trusted Vector NTI® tools, Vector NTI® Express Designer enables rational bio-design on the most popular computing architectures, including native Mac OSX 10.6+, Windows XP, and Windows 7 operating systems. Plug-in architecture allows users to have confidence that additional features and functionality can be added to the platform and deliver more value over time. And automatic updating ensures that users will be automatically notified of updates and given the option to download new or updated plug-ins, so that they will always be running the latest, most complete software package available.