Shop All C18 Reversed Phase LC Columns

Syncronis™ C18 Columns Thermo Scientific™

Achieve repeatable and consistent liquid chromatography (LC) separations using Thermo Scientific™ Syncronis™ C18 columns. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and ensure robust, high-resolution separations. Double end-capping provides extra surface coverage and inertness toward basic compounds. Manufactured and rigorously tested in ISO 9000 facilities, these columns are designed to meet a range of analytical needs including fast method development, quantitative analysis, and quality control.

EASY-Spray™ HPLC Columns Thermo Scientific™

Ensure robust nano and capillary flow LC-MS with Thermo Scientific™ EASY-Spray™ LC Columns. The integrated column/emitter design eliminates dead volume and is temperature-controlled for maximum reliability and performance. Rigourously tested to ensure maximum quality, these columns are designed for maximum simplicity and ease-of-use.

BETASIL™ C18 Preparative HPLC Columns Thermo Scientific™

Deliver the high surface area with high bonded phase coverage for your scale up purification needs with Thermo Scientific™ BETASIL™ C18 preparative HPLC columns. Our columns come in a wide range of dimensions to suit your application needs.

Hypersil™ BDS C18 Columns Thermo Scientific™

For a robust, general-purpose column to use in a wide range of applications, choose Thermo Scientific™ Hypersil™ BDS C18 HPLC Columns. These economical columns feature reduced silanol activity and provide exceptional reliability for QA/QC labs. Built on the renowned Hypersil silica backbone, the base-deactivated silica is one of the most popular packing materials available.

For more challenging separations that require improved chromatographic performance, use Thermo Scientific™ Hypersil GOLD™ columns as an alternative.

Hypersil GOLD™ aQ C18 Polar Endcapped HPLC Columns Thermo Scientific™

Retain and resolve polar analytes using Thermo Scientific™ Hypersil GOLD™ aQ Polar Endcapped C18 columns. These columns provide excellent peak shape, even with challenging reversed phase separations using highly aqueous mobile phases.

Hypersil GOLD™ C18 Selectivity HPLC Columns Thermo Scientific™

Achieve exceptional peak shape and resolution for your HPLC and LC/MS applications with Thermo Scientific™ Hypersil GOLD™ HPLC columns. These endcapped, ultrapure, silica-based columns deliver significant reduction in peak tailing using generic gradients with C18 selectivity. With their excellent resolution, efficiency, and sensitivity, Hypersil GOLD columns give you confidence in the accuracy and quality of your analytical data.

Accucore™ XL C18 HPLC Columns Thermo Scientific™

Optimize conventional HPLC methods with Thermo Scientific™ Accucore™ XL C18 LC Columns. Rugged 4µm solid-core particles ensure very high efficiencies within standard HPLC pressure limits. The high bonded phase coverage provides optimal retention of a broad range of nonpolar analytes across multiple applications. Robust bonding technology and automated packing procedures ensure excellent reproducibility and long column lifetimes.

Hypersil GOLD™ VANQUISH™ C18 UHPLC Columns Thermo Scientific™

Achieve even greater power of separation, speed, and throughput using Thermo Scientific™ Hypersil GOLD™ VANQUISH™ C18 UHPLC columns. These reversed-phase columns were developed in conjunction with the Vanquish UHPLC system to take advantage of the system's extended pressure capabilities and robustness. The result is a new level of separation, speed and throughput that solve analytical challenges of analyzing complex matrices using liquid chromatography (LC) and LC-MS.

Hypersil™ ODS C18 Columns Thermo Scientific™

Choose Thermo Scientific™ Hypersil™ ODS C18 HPLC Columns for a general purpose C18 phase to use in a broad range of applications.

Hypersil stationary phases are recognized as an industry standard in HPLC. Proven as an effective analytical tool, the classical Hypersil phases are well established and referenced in many HPLC methods worldwide. Quality is assured by manufacture under ISO 9001-2000 quality guidelines.

For more challenging separations that require improved chromatographic performance, we recommend the use of Thermo Scientific™ Hypersil GOLD™ columns as an alternative.

HyPURITY™ C18 HPLC Columns, 3µm Particle Size

Thermo Scientific™ HyPURITY™ C18 HPLC Columns are available in limited dimensions. Please contact Customer Service for more details.

Acclaim™ PepMap™ 100 C18 HPLC Columns Thermo Scientific™

Generate high-resolution analyses of tryptic, natural, and synthetic peptides using Thermo Scientific™ Acclaim™ PepMap™ 100 C18 LC Columns. These columns are often used for LC-MS/MS peptide mapping for protein identification, biomarker discovery, and systems biology. Due to their high loading capacity, Acclaim PepMap 100 C18 columns are exceptionally suitable for the analysis of low abundant peptides in complex proteomics samples. Most of these C18 columns are pre-assembled with Thermo Scientific™ nanoViper™ Fingertight Fittings for easy installation. Classic columns are available as well.

Accucore™ Vanquish™ C18+ UHPLC Columns, 1.5µm Thermo Scientific™

Choose Thermo Scientific™ Accucore™ Vanquish™ C18+ UHPLC columns, containing uniquely efficient 1.5 µm solid core particles for use with the Thermo Scientific™ Vanquish™ UHPLC system. Founded on state-of-the-art Core Enhanced Technology™, this sub-2 μm particle next-generation column has ultra-short diffusion paths that result in extremely efficient separations. This high efficiency enables fast separation and the resolution of complex mixtures. In concert with Vanquish systems, these columns deliver more results with better separations, thereby enhancing workflows and productivity.

Accucore™ aQ C18 Polar Endcapped HPLC Columns Thermo Scientific™

Separate polar compounds with improved speed and resolution using Thermo Scientific™ Accucore™ aQ C18 Polar Endcapped LC columns. Rugged 2.6µm solid-core particles enable fast, high-efficiency separations at low backpressures. The polar endcapped C18 stationary phase provides optimal retention of polar analytes and is fully compatible with 100% aqueous mobile phases. Robust bonding technology and automated packing procedures ensure excellent reproducibility and long column lifetimes.

Hypersil™ ODS-2 C18 Columns Thermo Scientific™

Use this well-tested, dependable L1. Thermo Scientific™ Hypersil™ ODS-2 C18 HPLC Columns are an alternative to older column brands commonly referenced in validated methods.

Hypersil stationary phases are recognized as an industry standard in HPLC. Proven as an effective analytical tool, classical Hypersil phases are well established and referenced in HPLC methods. Quality is assured by manufacture under ISO 9001-2000 quality guidelines.

For more challenging separations that require improved chromatographic performance, use Thermo Scientific™ Hypersil GOLD™ columns.

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