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ArrayScan™ Live Cell Module (Thermo Scientific™)

The Thermo Scientific™ ArrayScan™ Live Cell Module provides full control of temperature (ambient to 45°C), CO2 (0-10% ) and added humidity (>90% RH) to the sample chamber to maintain cell health for experiments with living cells or tissues. Therefore, cell physiology and motion can be monitored over seconds, minutes, hours or days .

Features of the ArrayScan Live Cell Module :

• Full Environmental Control—Complete environmental control (CO2, humidity, and temperature) with full reporting of CO2 and temperature.
• Kinetic Capabilities—Cell tracking with powerful kinetic analysis software provides numerous motility and kinetic calculations at the cell and well levels.
• Zeiss™ Definite Focus is a hardware-based autofocus system that maintains focus while supporting long-term imaging of live cells.

The ArrayScan Live Cell Module provides an environment similar to that of a tissue culture incubator. A proprietary cell tracking algorithm, built into the software, allows for kinetic measurements at the cell and well level.

ArrayScan™ Brightfield Module (Thermo Scientific™)

The Thermo Scientific™ ArrayScan™ Brightfield Module is an affordable option that adds white light illumination to high content screening (HCS) experiments. It allows imaging of unlabeled samples to quantify morphological features and the resulting data can be interleaved with fluorescence data from the same sample. The ArrayScan Brightfield Module has integrated software control to capture, focus, and analyze transmitted light images at single or multiple timepoints.

Features of the ArrayScan Brightfield Module :

• Capture, analyze, and visualize transmitted light images interleaved with fluorescence images
• Label-free detection
• Autofocus in transmitted light mode permitting imaging on multiple plate types, cell lines and magnifications
• Color composites can be used to verify location of fluorescent targets within a cell or organism

The ArrayScan Brightfield Module is fully integrated with the ArrayScan HCA Reader software (Thermo Scientific™ HCS Studio™ Cell Analysis Software) enabling the capture, analysis, and visualization of transmitted light images interleaved with fluorescence images at single or multiple time points.

EVOS™ XL Core Configured Microscope (Invitrogen™)

The EVOS XL Core Imaging System is a digital transmitted-light inverted imaging system for cell and tissue culture applications and routine cell maintenance. Its simple user interface drives a color camera and high-quality optical system that delivers high-definition images with exceptional ease. Equipped with 4X, 10X, and 20X long working distance (LWD) phase contrast (PH) objectives, the all-in-one EVOS XL Core system is an ideal microscope for basic imaging needs. With a small footprint, an articulated monitor, and ergonomic design, it is a perfect addition to any cell culture room or facility.

The EVOS XL Core Imaging System offers these important advantages:
• Easy installation; no maintenance, assembly, alignment, or calibration
• 4X, 10X, and 20X LWD PH objectives that are ideal for tissue culture microscopy
• A fixed stage for flexibility in imaging different cell culture vessels
• Fits and operates inside cell culture hoods
• All-in-one design: digital camera, precision optics, LCD display, and USB storage

Imaging anywhere
The EVOS XL Core system is an integrated transmitted-light inverted imaging system that combines high-quality optics, a 12.1-inch high-resolution LCD display, and a digital color camera. Images are seamlessly acquired through the user interface using a mouse and the integrated software that includes a variety of features, such as color temperature control. All images can be saved onto the USB device in JPEG, BMP, or TIFF formats. Applications suited for the EVOS XL Core system include basic imaging of live and fixed cells, tissue culture needs (confluence, density, and growth), stem cell isolation, and analysis of stained tissue slices.

The EVOS imaging systems are built from the ground up to maximize performance and optimize workflow. You will be astonished at how easy this system is to operate and amazed how good your images look.

Versatile
While the microscope comes equipped with three objectives (4X, 10X, and 20X LWD PH), the four-position objective turret can be configured to meet additional needs using our full range of LWD phase contrast and coverslip-corrected objectives. LWD PH objectives are available from 1.25X to 40X. The compact footprint makes it easy to use the EVOS XL Core system wherever needed; the entire system can be easily moved into a cell culture hood or glove box. The universal stage provides maximum flexibility for slides, culture dishes, and flasks. An optional mechanical stage affords more precise handling and positioning of multi-well plate vessels.

Easy to use and reliable
The EVOS XL Core Imaging System is plug-and-play. In addition to an exceptionally easy set-up and installation, it requires no warm-up or cool-down periods. The LED light source offers exceptional stability and durability--so you can turn the unit on and off whenever you need to image a sample. The LED bulbs are rated for >50,000 hours (~17 years), compared to 300 hours for a typical mercury bulb and 1,500 hours for a metal halide bulb. The long lifetime and low energy consumption translate into lower operating costs compared to instruments with conventional light sources. Finally, the advanced ergonomic design of the EVOS systems removes the strain of conventional microscopes in imaging, enables shared viewing, and makes moving the units easy.

Learn more about the EVOS XL Core Imaging System and most recent software ›
See the optional mechanical stage ›
Explore the entire EVOS line of imaging systems and accessories ›

Unit includes:
• EVOS XL Core Imaging System with Fixed Stage
• EVOS Obj, Inf Plan Achro 4X LWD PH, 0.13NA/16.9WD (AMEP4632)
• EVOS Obj, Inf Plan Achro 10X LWD PH, 0.25NA/6.9WD (AMEP4633)
• EVOS Obj, Inf Plan Achro 20X LWD PH, 0.40NA/6.8WD (AMEP4634)
• Glass stage plate
• Wireless mouse
• Power adaptor, cord, and universal power plug adapters
• USB flash drive (includes User Guide and Quick Start Guide)
• Dust cover
• 3-mm hex driver L-shaped key

System highlights

Optics: infinity-corrected optical system, RMS-threaded objectives with 45-mm parfocal distance
Objectives: 4X, 10X, and 20X LWD PH achromat objectives. A wide selection of other high-quality LWD and coverslip-corrected objectives is available.
Illumination: adjustable intensity LED (>50,000-hour life)
Contrast methods: transmitted light (brightfield and phase contrast)
Objective turret: 4-position, manual control
Condenser: 3-position turret for brightfield and phase contrast
Condenser working distance: 60 mm
Stage: fixed stage
Focus mechanism: coaxial focus knobs with tension control. Course focus: 38 mm/rev. Fine focus: 0.2 mm/rev, precision 0.002 mm.
LCD display: 12.1-inch high-resolution (1024 x 768 pixels) color monitor with adjustable tilt
Camera: color, 2048 x 1536, 3.1 megapixels
Image acquisition: embedded operating system with software for image capture and saving via mouse or front-mounted manual buttons
Captured images Color camera: 24-bit full color TIFF or PNG; jpeg, bmp (2048 x 1536 pixels)
Output ports: 2 USB 2.0 ports
Power supply: AC adaptor; Input: 100-240 V, 47-63 Hz; Output: 12 V DC/2.0 A, 24W max
Dimensions: Height: 533 mm (21.0 in); Depth: 406 mm (6.0 in); Width: 318 mm (12.5 in)
Weight: 9.1 kg (20.1 lbs)

ArrayScan™ Liquid Handling Module (Thermo Scientific™)

The Thermo Scientific™ ArrayScan™ Liquid Handling Module is designed to work with the Thermo Scientific™ ArrayScan™ Live Cell Module, expanding the flexibility of the platform for analysis of complex cellular states of cells. The ArrayScan Liquid Handling Module has functionalities to aspirate, dispense, and mix, from four deck locations. The module is capable of single-tip aspirate and dispense at any location, creating a highly flexible instrument. Compatible with 6-well, 8-well, 24-well, 96-well, and 384-well plates, the ArrayScan Liquid Handling Module utilizes disposable tips with a dispense volume range of 3 to 200μL.

Features of the ArrayScan Liquid Handling Module:

• Compatible with 6-well, 8-well, 24-well, 96-well, and 384-well plates, the module utilizes disposable tips with a dispense volume range of 3 to 200μL
• Full function liquid handling from any plate or trough (3 plate and 1 quarter trough)
• Industry standard arm with single pipette tip driven by syringe pump (e.g., aspirate, dispense)
• Compatible with all ArrayScan Modules
• Dynamic access to compound and assay plate
• One-to-many and many-to-one transfer scenarios are supported

Includes:

ArrayScan Liquid Handling Module : Automated, single-tip, liquid handling robot module for the Thermo Scientific™ ArrayScan™ High Content Analysis (HCA) Readers using disposable tips (standard and liquid level sensing) to both aspirate and dispense from multiple deck and live cell chamber locations.

EVOS™ XL Core Configured Microscope with Mechanical Stage (Invitrogen™)

The EVOS XL Core Imaging System is a digital transmitted-light inverted imaging system for cell and tissue culture applications and routine cell maintenance. Its simple user interface drives a color camera and high-quality optical system that delivers high-definition images with exceptional ease. Equipped with 4X, 10X, 20X, and 40X long-working–distance (LWD) phase contrast (PH) objectives and a mechanical stage, the all-in-one EVOS XL Core system is an ideal microscope for basic imaging needs. With a small footprint, an articulated LCD monitor, and ergonomic design, it is a perfect addition to any cell culture room or facility.

The EVOS XL Core Imaging System offers these important advantages:
• Easy installation; no maintenance, assembly, alignment, or calibration
• 4X, 10X, 20X, and 40X LWD PH objectives that are ideal for tissue culture microscopy
• A mechanical stage for precise vessel positioning, including of multi-well plates
• Fits and operates inside cell culture hoods
• All-in-one design: digital camera, precision optics, LCD display, and USB storage

Imaging anywhere
The EVOS XL Core system is an integrated transmitted-light inverted imaging system that combines high-quality optics, a 12.1-inch high-resolution LCD display, and a digital color camera. Images are seamlessly acquired through the user interface using a mouse and the integrated software that includes a variety of features, such as color temperature control. All images can be saved onto the USB device in JPEG, BMP, or TIFF formats. Applications suited for the EVOS XL Core system include basic imaging of live and fixed cells, tissue culture needs (confluence, density, and growth), stem cell isolation, and analysis of stained tissue slices.

EVOS imaging systems are built from the ground up to maximize performance and optimize workflow. You will be astonished at how easy this system is to operate and amazed how good your images look.

Versatile
While the microscope comes equipped with three objectives (4X, 10X, 20X, and 40X LWD PH), the four-position objective turret can be configured to meet additional needs using our full range of LWD phase contrast and coverslip-corrected objectives. LWD PH objectives are available from 1.25X to 40X. The compact footprint makes it easy to use the EVOS XL Core system wherever needed; the entire system can be easily moved into a cell culture hood or glove box. The mechanical stage affords precise handling and positioning and is particularly suitable for multi-well plate vessels.

Easy to use and reliable
The EVOS XL Core Imaging System is plug-and-play. In addition to an exceptionally easy set-up and installation, it requires no warm-up or cool-down periods. The LED light source offers exceptional stability and durability--so you can turn the unit on and off whenever you need to image a sample. The LED bulbs are rated for >50,000 hours (~17 years), compared to 300 hours for a typical mercury bulb and 1,500 hours for a metal halide bulb. The long lifetime and low energy consumption translate into lower operating costs compared to instruments with conventional light sources. Finally, the advanced ergonomic design of the EVOS systems removes the strain of conventional microscopes in imaging, enables shared viewing, and makes moving the units easy.

Learn more about the EVOS XL Core Imaging System and most recent software ›
Explore the entire EVOS line of imaging systems and accessories ›

Unit includes:
• EVOS XL Core Imaging System with Mechanical Stage
• EVOS Obj, Inf Plan Achro 4X LWD PH, 0.13NA/16.9WD (AMEP4632)
• EVOS Obj, Inf Plan Achro 10X LWD PH, 0.25NA/6.9WD (AMEP4633)
• EVOS Obj, Inf Plan Achro 20X LWD PH, 0.40NA/6.8WD (AMEP4634)
• EVOS Obj, Inf Plan Achro 40X LWD PH, 0.65NA/3.1WD (AMEP4635)
• Wireless mouse
• Power adaptor, cord, and universal power plug adapters
• USB flash drive (includes User Guide and Quick Start Guide)
• Dust cover
• 3-mm hex driver L-shaped key
• Mechanical stage instructions

System highlights

Optics: infinity-corrected optical system, RMS-threaded objectives with 45-mm parfocal distance
Objectives: 4X, 10X, 20X, and 40X LWD PH achromat objectives. A wide selection of other high-quality LWD and coverslip-corrected objectives is available.
Illumination: adjustable intensity LED (>50,000-hour life)
Contrast methods: transmitted light (brightfield and phase contrast)
Objective turret: 4-position, manual control
Condenser: 3-position turret for brightfield and phase contrast
Condenser working distance 60 mm
Stage: mechanical stage
Focus mechanism: coaxial focus knobs with tension control. Course focus: 38 mm/rev. Fine focus: 0.2 mm/rev, precision 0.002 mm.
LCD display: 12.1-inch high-resolution (1024 x 768 pixels) color monitor with adjustable tilt
Camera: color, 2048 x 1536, 3.1 megapixels
Image acquisition: embedded operating system with software for image capture and saving via mouse or front-mounted manual buttons
Captured images: Color camera: 24-bit full color TIFF or PNG; jpeg, bmp (2048 x 1536 pixels)
Output ports: 2 USB 2.0 ports
Power supply: AC adaptor; Input: 100-240 V, 47-63 Hz; Output: 12 V DC/2.0 A, 24 W max
Dimensions: Height: 533 mm (21.0 in); Depth: 406 mm (6.0 in); Width: 318 mm (12.5 in)
Weight: 9.6 kg (21.2 lbs)

CellInsight™ CX7 High Content Analysis Platform (Thermo Scientific™)

The Thermo Scientific™ CellInsight™ CX7 High Content Analysis (HCA) Platform is a fast, automated cellular imaging and analysis platform designed for quantitative microscopy.

The CellInsight CX7 HCA Platform offers an integrated way to develop and automate high content assays using a combination of 5-color brightfield and 7-color fluorescence imaging in confocal or wide-field modes. See how the CellInsight CX7 platform compares to other high content analysis platforms from Thermo Fisher Scientific >

Features of the CellInsight CX7 HCA Platform
• 7-channel fluorescent imaging
• 5-channel bright-field imaging
• 7-channel confocal imaging
• Software and laser-based autofocus for consistent scan times
• Configured for fully automated plate handling and scanning

Capabilities
• Addresses hundreds of assay types with flexible software and hardware tools
• Scan and analyze microscope slides or most SBS-standard format microplates
• Use HCS Studio software for integrated instrument control and data analysis
• Achieve the fastest time to results by using intelligent acQuisition (iQ) real-time analysis feedback
• Compatible with Molecular Probes™ fluorescent detection reagents

Hardware and Software
• Stable and reliable light source enables reduced variability, increased data quality, and decreased operating costs
• Broad reagent options with seven-color excitation from violet to near IR for assay multiplexing
• Dual mode focusing using Software and Laser Autofocus methods to address both labelled and unlabeled sample types
• Multi-mode imaging allows for wide-field, bright-field, and confocal imaging in one run
• HCS Studio Cell Analysis Software is an integrated instrument control, visualization, and analysis software package for novice to advanced users
• Scalable with Store Image and Database Software and optional Orbitor RS Microplate handler

ArrayScan™ Emission Filter Wheel Module (Thermo Scientific™)

The Thermo Scientific™ ArrayScan™ Emission Filter Wheel Module, with appropriate filters, can precisely capture the spectral maximum of an excited fluorochrome allowing for an increased signal-to-noise ratio and enhancing image resolution when performing fluorescence-based high content analysis. Rapid, but precise turret movement allows for multiple wavelengths to be detected and recorded on a sample within seconds.

EVOS™ M5000 Imaging System (Invitrogen™)

The EVOS M5000 Imaging System is a fully integrated digital inverted benchtop microscope for four-color fluorescence, transmitted-light, and color imaging. With interchangeable optics with autofocus, single-click multi-channel image acquisition, and an interface designed for usability, you can acquire publication-quality images in minutes. And with a range of post-capture tools, from brightness/contrast to annotations and automated cell counting, the EVOS M5000 system is an exceptionally versatile microscope and ideal for a broad range of imaging applications.

The EVOS M5000 Imaging System offers you these important advantages:
• Easy installation—no maintenance, assembly, alignment, or calibration
• User-defined four-color fluorescence, transmitted light, and color applications
• Autofocus, Z-stack capability, time-lapse imaging, and single-click multi-channel capture
• On-board software for acquisition, analysis, and automated cell counting

Fully integrated imaging system
The EVOS M5000 microscope combines precision components with a unique modern design functionality that enables high-quality fluorescence and color imaging anywhere with unprecedented flexibility. It is a fully integrated imaging system that combines precision optics, an 18.5” high-resolution articulated LCD monitor, and a highly sensitive 3.2 MP monochrome CMOS camera (2048 x 1536) with 3.45-µm pixel resolution. The monochrome camera affords the best sensitivity for detection of faint fluorescence signals and allows quantitative analysis. At the same time the condenser includes a novel LED-based RGB illumination scheme that enables high-quality, low-noise color image acquisition using the same monochrome sensor, enabling rendering of true color in transmitted light, which is beneficial when imaging stained tissue samples such as H&E stained tissue sections.

Versatile and highly configurable
With a five-position objective turret and the ability to acquire images in four fluorescence channels, transmitted light phase-contrast, and color, the optical system can be easily configured to meet your needs. Choose from our broad range of high-quality long-working-distance and coverslip-corrected objectives for use with plastic vessels or glass sides. Available from 1.25X to 100X magnification with achromat, fluorite, or apochromat correction, together with over twenty LED light cubes, the sample imaging options are limitless. Interchangeable vessel holders accommodate most vessel types and sizes, including slides, multi-well plates, culture flasks, and Petri dishes, and afford precise control and sample alignment by the automated stage.

Easy to use and reliable
The EVOS M5000 Imaging System is powerful, yet offers the simplicity of plug-and-play. It requires no warm-up or cool-down periods, allowing you to capture images in minutes. The environmentally safe, mercury-free LED lights are rated for 50,000 hours and afford exceptional stability and durability—you can turn the unit on and off whenever you need to image a sample. The long lifetime and low energy consumption translate into significantly lower operating costs compared to instruments with conventional light sources. Designed by biologists for biologists with a modern, icon-based interface, the EVOS M5000 microscope is remarkably easy to use. Following seamless image acquisition, you can analyze, edit, and annotate your images using a set of convenient tools available in both live mode and for saved images. To easily count the number of DAPI-stained cells, we have developed an automated cell count app. Once you have finished editing and analysis, save the images and data to the embedded hard-drive, an external USB device, or a local network.

The EVOS imaging systems are built from the ground up to maximize performance and optimize workflow. You will be astonished at how easy it is to operate and amazed at how extraordinary your images look on-screen.

More information about the EVOS M5000 Imaging System ›
Explore the entire EVOS line of imaging systems, accessories, and offers ›

CellInsight™ CX7 LZR High Content Analysis Platform (Thermo Scientific™)

The Thermo Scientific CellInsight CX7 LZR High Content Analysis (HCA) Platform is a fast, laser-based, automated cellular imaging and analysis platform designed for quantitative microscopy. The CellInsight CX7 LZR HCA Platform offers a more powerful and integrated way to develop and automate high content assays using a combination of 5-color bright-field and 7-color fluorescence imaging in confocal or wide-field modes. With laser illumination, the Cell Insight LZR HCA Platform enables researchers to image faster in both wide-field and confocal mode.

Features of the CellInsight CX7 HCA Platform:
• 7-channel fluorescent imaging with laser illumination
• 5-channel bright-field imaging
• 7-channel confocal imaging
• Software and laser-based autofocus for consistent scan times
• Configured to accept optional modules for fully automated plate handling and live cell on-board environmental control

Capabilities
• Addresses hundreds of assay types with flexible software and hardware tools
• Scan and analyze microscope slides or most SBS-standard format microplates
• Use integrated HCS Studio software for instrument control and data analysis
• Achieve the fastest time to results by using intelligent acQuisition (iQ) real-time analysis feedback
• Compatible with Molecular Probes fluorescent detection reagents

Hardware and software
• High-output laser excitation light
• Broad reagent options with 7-color excitation from violet to near IR for assay multiplexing
• Dual mode focusing using Software and Laser Autofocus methods to address both labelled and unlabeled sample types
• Multi-mode imaging allows for wide-field, bright-field, and confocal imaging in one run
• HCS Studio Cell Analysis Software is an integrated instrument control, visualization, and analysis software package for novice to advanced users
• Scalable with Store Image and Database Software (not included) and optional Orbitor RS Microplate handler (not included)

ArrayScan™ Confocal and Objective Module, seven-color LED (Thermo Scientific™)

The Thermo Scientific™ ArrayScan™ Confocal and Objective Module enables the Thermo Scientific™ ArrayScan High Content Analysis (HCA) Readers to be operated in confocal mode while increasing optical resolution. Featuring the latest in high-speed Nipkow spinning disk technology and a variable pinhole, the ArrayScan Confocal and Objective Module enables finer control over image acquisition across a range of objectives (magnifications) in order to balance image quality and performance for the most demanding cell biology experiments; e.g., stem cell colonies, tissues, and 3D microenvironments.

Features of the ArrayScan Confocal and Objective Module :

• Flexibility in Hardware—Dual patterned disks allow users to define different confocal resolutions depending on sample type. The system also enables imaging in widefield and confocal modes in one run.
• Next-generation CARV disk with high-speed Nipkow design with 40μm and 70μm pinholes are designed for low- and high-NA flexibility.
• Efficient design–Four-color, LED light engine for solid-state illumination eliminates the issues associated with lasers (alignment, heat, cost).
• Upgradeable–Build upon your current ArrayScan HCA Reader investment and add new functionality.

EVOS™ M7000 Imaging System (Invitrogen™)

The EVOS M7000 Imaging System is a high-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system. It was developed to meet today’s expectations for image quality, user interface interactions, data generation speed and flexibility, and end-user value. The powerful and time-saving acquisition tools with enhanced autofocus algorithms and automated routines for microwell plate assays, time-lapse live cell imaging, area scanning in time lapse and Z-stacks in scan mode, and a superb optomechanical design enable the generation of publication-quality images and data with just a few clicks when and where needed.

The EVOS M7000 Imaging System offers these advantages:
• Outstanding image quality and versatility with a 5-position objective turret, 4-color LED fluorescence and transmitted light channels, and 3.2 MP CMOS color and B/W cameras
• Exceptional usability with fully automated X/Y scanning stage, autofocus, and acquisition routines
• High-speed image acquisition coupled with multi-position well scanning, and Z-stack and tile-stitch options lend power and flexibility to your data generation
• Fully integrated time-lapse live cell imaging using the optional EVOS Onstage Incubator for precise control of temperature, gases for normoxic or hypoxic conditions, and humidity
• Powerful image analysis capabilities for cell segmentation and quantification with the optional Celleste Image Analysis Software

Fully automated imaging system
The EVOS M7000 system combines and integrates precision components with a unique modern design functionality that enables high-quality automated fluorescence imaging anywhere with unprecedented workflow efficiency. Full automation of the precision X/Y-stage movement; changing of the 4 LED fluorescent light cubes, 5-position objective turret, focus, and exposure; and switching of the dual camera make the EVOS M7000 system an exceptional platform for a variety of demanding imaging applications. Through the intuitive acquisition interface, you can program the EVOS M7000 system to run well-plate scanning, time lapse experiments, and tile-stitch/montage area scans in Z-stack and/or time-lapse modes in your vessel of choice. For live cell imaging over multiple hours or days, the optional EVOS Onstage Incubator, which functions as an environmental chamber on top of the microscope stage, is operated seamlessly from within the instrument interface. The EVOS M7000 system is compatible with all accessories for the predecessor EVOS FL Auto imaging system.

Versatile and highly configurable
With a 5-position objective turret and the ability to simultaneous acquire images in four fluorescence channels plus transmitted light, the optical system can be easily configured to meet your needs. Choose from our broad range of high quality coverslip-corrected and long-working-distance objectives for use with plastic vessels or glass sides. Available from 1.25X to 100X magnification in achromat, fluorite, or apochromat models, together with over twenty LED light cubes, the sample imaging options are limitless. Dual monochrome and color high-sensitivity dual CMOS cameras enable seamless imaging of both fluorescent and chromogenically stained samples. Interchangeable vessel holders accommodate most vessel types and sizes, including slides, multi-well plates, culture flasks, and Petri dishes, and afford precise control and sample alignment by the automated stage. The vessel creation wizard in the user interface enables creation of profiles for custom sample vessels.

Powerful software
The EVOS M7000 software presents users with an extensive suite of tools for acquisition, visualization, and analysis. The user interface was designed with a strong emphasis on usability, including an option to view samples in a single field mode (Field View) or in a window that covers a much larger area (Area View). By using a zoom function, the Area View size can be adjusted. A user can explore a large sample area at low magnification, define regions of interest, and then seamlessly transition to the Scan function in Automate Mode and execute an area scan at higher magnification.

The enhanced power of the EVOS M7000 system enables more demanding automated acquisition routines like area scanning in time lapse and Z-stacks in scan mode to be performed. Visualization capabilities include multi-field image viewing gallery, mosaic tiling and tile stitching options, Z-stack visualization, and a video recording and movie maker/editor for time lapse sequences. The EVOS M7000 system is fully compatible with the EVOS Onstage Incubator environmental chamber for control of temperature, gases, and humidity. With the ability generate both hypoxic and normoxic conditions, it is possible to study live cells over extended periods with highly flexible time lapse automation routines.

For users needing more powerful image analysis capabilities, images acquired on the EVOS M7000 system can be analyzed directly using the optional Celleste Image Analysis Software. Celleste software offers powerful tools for image segmentation and classification that can be applied to a range of cell analysis applications for counting and measuring intensity, area, and shape changes over time, and more.

Smart LED illumination technology
All EVOS fluorescence imaging systems utilize our proprietary LED light cubes. This light engine outputs remarkable intensity over a short light path and delivers incomparable fluorophore excitation. Each light cube contains a precisely matched set of optical components to optimize the position, evenness, and intensity of the light beam. Digitally controlled LED light sources allow adjustment of illumination levels to the sample and experimental conditions to minimize the risk of photo-toxicity and photo-bleaching in time-lapse studies. Hard-coated filters give sharper edges and significantly higher transmission efficiencies than traditional soft-coated filters.

Easy to use and reliable
The EVOS M7000 Imaging System is powerful, yet offers the simplicity of plug-and-play. Like other EVOS systems, it requires no warm-up or cool-down periods. The LED light source guarantees exceptional stability and durability, so you can turn the unit on and off whenever you need to image a sample. The environmentally safe, mercury-free LED bulbs are rated for >50,000 hours, compared to 300 hours for a typical mercury bulb and 1,500 hours for a metal halide bulb. The long lifetime and low energy consumption translate into significantly lower operating costs compared to instruments with conventional light sources. The EVOS M7000 system is powered by an external Dell PC with an Intel Core i7-8700 processor, 32 GB DDR4 RAM, 512 GB PCIe SSD, and NVIDIA Quadro P1000 with 4 GB discrete video graphics running Windows 10, designed to operate with touchscreen monitor and microscope. Whether acquiring single images or setting up automated routines, the EVOS M7000 system is remarkably easy to use and run. The 1920 x 1080 pixel resolution 23" LCD touch screen monitor enables “finger swipes” to expand or zoom in on images, and moving between microwell plate wells is done by a single touch. Operation is also also fully controllable via mouse.

The EVOS imaging systems are built from the ground up to maximize performance and optimize workflow. You will be astonished at how easy it is to operate and amazed at how extraordinary your images look on-screen.

Explore the entire EVOS line of imaging systems, accessories, and offers ›

System and hardware specifications
Optics: infinity‐corrected optical system; RMS‐threaded objectives with 45-mm parfocal distance
Imaging mode: fluorescence, brightfield, color brightfield, and phase contrast
Illumination: five position chamber for 4 fluorescence light cubes plus brightfield; light cubes with integrated hard coated filter set and LED light source with >50,000 hour life; broad selection of standard and specialty light cubes
Imaging methods: single color, multi-color, area scan with montage or tile-stitch, time lapse, Z-stacking, movie capture
Objective capacity: 5‐position turret
Objectives (not included): wide selection of high‐quality LWD and coverslip‐corrected objectives
Condenser: 60-mm long working distance condenser, 4 position turret with a clear aperture and 3 phase annuli
Stage: motorized X/Y scanning stage; travel range 120 mm x 80 mm with sub‐micron resolution, drop‐in inserts to receive vessel holders and lock down holders to fix sample in place during long scans
Focus mechanism: automated focus mechanism with sub‐micron resolution
LCD display: 23" high‐resolution touch screen color monitor (also fully controllable via mouse); 1920 x 1080 pixel resolution
Cameras: high-sensitivity 3.2 MP (2048 x 1536) monochrome CMOS sensor with 3.45 µm pixel resolution;high-sensitivity 3.2 MP (2048 x 1536) color CMOS sensor with 3.45 µm pixel resolution
Computer: external Dell PC with an Intel Core i7-8700 processor, 32 GB DDR4 RAM, 512 GB PCIe SSD, and NVIDIA Quadro P1000 with 4 GB discrete video graphics running Windows 10, designed to operate with touchscreen monitor and microscope
Captured images: 16‐bit RAW monochrome: TIFF, PNG; 8-bit: TIFF, PNG, JPG; movies and time‐lapse: AVI, WMV
Output ports: Computer: 1 x USB 3.1 Gen 2 Type-C; 5 x USB 3.1 Gen 1 Type-A; 4 x USB 2.0 Type-A; 1 Serial; 2 Display Ports 1.2; 1 RJ-45; 2 PS/2; 1 UAJ; 1 Line-out
Networking capability: connection through Windows/SMB network via an Ethernet cable connection
Power supply: 24 V AC adapter with country‐specific power cords
Dimensions (L x W x H): 18 x 14 x 13 inches (457 x 330 x 356 mm)
Weight: 16/35 (kg/lb)

ArrayScan™ 7-Color LED Module for ArrayScan™ HCA Readers (Thermo Scientific™)

The Thermo Scientific™ ArrayScan™ 7-Color LED Module for ArrayScan™ HCA Readers (600-800 series) is a seven color, direct coupled, Light Emitting Diode (LED) light source designed for high performance and ultra-reliability to excite fluorochromes that are blue, cyan, green, yellow, orange-red, scarlet, far red, and near IR.

Features of the ArrayScan 7-Color LED Module for ArrayScan HCA Readers:

• Spectral flexibility—spanning the visible spectrum from UV through near-IR, the ArrayScan 7-Color LED Module can use the available filter combinations to provide for a multitude of excitation and emission combinations
• Spectral separation—avoid bleed through between channels by using excitation and emission wavelengths that have bands separated enough to prevent spectral overlap

Includes:

• To be used with Thermo Scientific™ HCS Studio™ Cell Analysis Software (version 2.0 or greater) and minimum computer specifications
• Filters and emission filter wheel

CellInsight™ CX7 High Content Analysis Platform and Store Standard Edition (Thermo Scientific™)

The Thermo Scientific™ CellInsight™ CX7 High Content Analysis (HCA) Platform is a fast, automated cellular imaging and analysis platform designed for quantitative microscopy.

This particular configuration includes the CellInsight CX7 HCA Reader along with HCS Studio™ Cell Analysis Software and Store Image and Database Management Software to visualize and share high content data and images. Two days of onsite training and a one year warranty and applications support are also included.

The CellInsight CX7 HCA Platform offers an integrated way to develop and automate high content assays using a combination of 5-color brightfield and 7-color fluorescence imaging in confocal or wide-field modes. See how the CellInsight CX7 platform compares to other high content analysis platforms from Thermo Fisher Scientific >

Features of the CellInsight CX7 HCA Platform
• 7-channel fluorescent imaging
• 5-channel bright-field imaging
• 7-channel confocal imaging
• Software and laser-based autofocus for consistent scan times
• Configured for fully automated plate handling and scanning

Capabilities
• Addresses hundreds of assay types with flexible software and hardware tools
• Scan and analyze microscope slides or most SBS-standard format microplates
• Use HCS Studio software for integrated instrument control and data analysis
• Achieve the fastest time to results by using intelligent acQuisition (iQ) real-time analysis feedback
• Compatible with Molecular Probes™ fluorescent detection reagents

Hardware and Software
• Stable and reliable light source enables reduced variability, increased data quality, and decreased operating costs
• Broad reagent options with seven-color excitation from violet to near IR for assay multiplexing
• Dual mode focusing using Software and Laser Autofocus methods to address both labelled and unlabeled sample types
• Multi-mode imaging allows for wide-field, bright-field, and confocal imaging in one run
• HCS Studio Cell Analysis Software is an integrated instrument control, visualization, and analysis software package for novice to advanced users
• Scalable with Store Image and Database Software and optional Orbitor RS Microplate handler

EVOS™ XL Core Imaging System

The EVOS XL Core Imaging System is a digital, transmitted light, inverted imaging system for cell and tissue culture applications and routine cell maintenance. Its color camera and high-quality optical system deliver high-definition images with exceptional ease. With a small footprint and an ergonomic design, the all-in-one EVOS XL system is ideal for basic imaging needs and a perfect addition to any cell culture room or facility.

The EVOS XL Core Imaging System offers you these important advantages:

• Easy installation; no maintenance, assembly, alignment, or calibration
• Configured for four objectives
• Fits and operates inside a cell culture hood
• All-in-one design: digital camera, precision optics, LCD display, and USB storage

Imaging Anywhere
The EVOS XL Core system is an integrated transmitted-light inverted imaging system that combines high-quality optics, a 12.1" high-resolution LCD display, and a digital color camera. Images are seamlessly acquired through the user interface using a mouse and the integrated software that includes a variety of features, such as color temperature control. All images can be saved onto the USB device in JPEG, BMP, or TIFF formats. Applications suited for the EVOS XL Core system include basic imaging of live and fixed cells, tissue culture determinations (confluence, density, and growth), stem cell isolation, and analysis of stained tissue slices.

The EVOS imaging systems are built from the ground up to maximize performance and optimize workflow. You will be astonished at how easy it is to operate and amazed at how extraordinary your images look on-screen.

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Versatile
The four-position objective turret can be configured to best meet your needs using our full range of long working distance (LWD) and coverslip-corrected objectives. LWD objectives are available from 4x to 40x, and our 2x objective allows viewing of the entire well of a 96-well plate. The compact footprint makes it easy to use the EVOS XL Core system wherever needed; the entire system can be easily moved into a cell culture hood or glove box. The EVOS XL Core system is designed with a universal stage that provides maximum flexibility for slides, culture dishes, and flasks. The optional mechanical stage affords more precise handling and positioning of multiwell plate vessels.

Easy to Use and Reliable
The EVOS XL Core Imaging System is plug-and-play. In addition to an exceptionally easy set-up and installation, it requires no warm-up or cool-down periods. The LED light source offers exceptional stability and durability—turn the unit on and off whenever you need to image a sample. The LED bulbs are rated for >50,000 hours (~17 years) of life, compared to 300 hours for a typical mercury bulb and 1,500 hours for a metal halide bulb. The long life and low energy consumption translate into significantly lower operating costs compared to instruments with conventional light sources. Finally, the advanced ergonomic design of the EVOS systems removes the strain associated with conventional microscopes, enables shared viewing, and makes moving the units easy.

Learn more about the EVOS XL Core Imaging System
Explore the entire EVOS line of imaging systems and accessories

System Highlights
Optics: infinity-corrected optical system, RMS-threaded objectives with 45 mm parfocal distance
Objectives (not included): wide selection of high-quality LWD and coverslip-corrected objectives
Illumination: adjustable intensity LED (>50,000-hour life per light cube)
Contrast methods: transmitted light (brightfield and phase contrast)
Objective turret: 4-position, manual control
Condenser: 3-position turret for brightfield and phase contrast
Condenser working distance: 60 mm
Stage: fixed stage
Focus mechanism: coaxial focus knobs with tension control
Course focus: 38 mm/rev
Fine focus: 0.2 mm/rev, precision 0.002 mm
LCD display: 12.1" high-resolution (1024 x 768 pixels) color monitor with adjustable tilt
Camera: Color, 1/2" 2048 x 1536 pixels, 3.1 Megapixels
Image acquisition: embedded operating system with software for image capture and saving via mouse or front-mounted manual buttons
Captured images: color camera; 24-bit full color; TIFF, PNG, jpeg, bmp; 2048 x 1536 pixels
Output ports: 2 USB 2.0 ports
Power supply: AC adaptor; input 100-240 V, 47-63 Hz; output 12 VDC/2.0 A 24 W max
Dimensions: height = 53.3 cm (21.0 in); depth = 40.6 cm (6.0 in); width = 31.8 cm (12.5 in)
Weight: 9.1 kg (20.1 lbs)

FLoid™ Cell Imaging Station

The FLoid® Cell Imaging Station is an affordable, user-friendly imaging solution for the quick detection and verification of fluorescently-labeled samples. The FLoid® Cell Imaging Station captures transmitted light and three-color fluorescent images of your cells and samples right at your benchtop. You do not need to be specially trained or have dedicated staff to operate it. An uncomplicated user interface, streamlined image acquisition process, and real-time, multicolor display allow even imaging novices to produce high-quality images with a few mouse clicks.

The FLoid® Cell Imaging Station offers you these important advantages:

Simplicity—Fully integrated system with intuitive, multilingual user interface
Speed—Get results in a snap, without warm-up, cool-down, or filter changes
Convenience—Capture and print images on your bench, rather than in the darkroom
Information—Find out about the most popular Molecular Probes® reagents and protocols via the user interface
Robustness—No moving parts and long life LEDs for reliable day to day use

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High Quality Imaging Anywhere in Your Lab
The FLoid® Cell Imaging Station is a fully integrated devise seamlessly combining high-quality optics, detection in three fluorescence channels as well as transmitted light, a widescreen LCD monitor, camera, image acquisition/processing software, and reagent information and protocols. It features a fixed, high-quality 20x plan fluorite objective, with additional magnification obtainable using the digital zoom. Fluorescence is captured in the three most commonly used channels (DAPI, FITC, and Texas Red filters). Transmitted light images automatically show cells in excellent contrast through a relief phase design, without loss of light. With its innovative light shield, ambient light is blocked so the FLoid® Cell Imaging Station can be placed wherever you need it most - in the tissue culture room, among other cell-based assay instruments, or on your lab bench. FLoid® Cell Imaging Station lets you bring imaging out of the darkroom.

Versatile and Easy to Use
The FLoid® Cell Imaging Station uses an open-stage design providing maximum vessel flexibility for slides, multi-well culture dishes, or even T75 flasks. A focus assist scale makes it easy to find the focus plane. Once samples are in focus, you can use the mouse to change light intensity and switch colors; there is also a scale bar that changes as the digital zoom level is changed, making it easy to estimate and compare sample sizes. The absolute magnification span is from 460X up to 1,840X using the digital zoom. Images can be printed directly using the optional printer, or saved for viewing in one of the four formats (JPEG, TIFF, BMP, or PNG) at a later time or with other software. With printer you can generate sticker-backed prints for immediate notebook mounting. The FLoid® Printer is not included with the FLoid® Cell Imaging Station and must be purchased separately.

Fast and Reliable
The FLoid® Cell Imaging Station requires no warm-up or cool-down periods. It uses LED light sources possessing exceptional stability and durability--so you can turn the FLoid® Cell Imaging Station on and off whenever you produce an image. Because there are no user-changeable parts, the system is exceptionally robust and no components will have "walked away" when you need them. By taking on everyday imaging tasks, the reliable FLoid® Cell Imaging Station helps you protect your investment in other expensive fluorescence equipment.

An Everyday-Use Imager for Every User
Now anyone can quickly start acquiring high-quality fluorescence images. To facilitate straightforward, intuitive operation, the FLoid® Cell Imaging Station features an icon-based user interface with easy-to-use image capture and processing screens, thumbnails of collected images, and quick reference icons. You can set all interface instructions, including protocols, to one of the six built in languages--English, Spanish, German, French, Italian, Japanese, and Chinese.

FLoid® Cell Imaging Station Places Information at your Fingertips
By incorporating the Molecular Probes® reagent selection guide, the FLoid® Cell Imaging Station simplifies fluorescent dye selection and cell staining. You can easily access detailed information on over 160 reagents in 20 application areas directly from the user interface. Each reagent has a quick reference protocol with icons and concise text for ease of use. These reagents have been validated for spectral compatibility with FLoid®, so you can obtain optimal images.

System specifications include:
Objective: Fixed 20X plan fluorite; numerical aperture (NA) = 0.45; working distance (WD) = 5.9 mm.
Color Channels: 4 channels (relief phase, blue, green, and red fluorescence)
Illumination: LED (50,000 hour life), adjustable intensity
Excitation: Blue channel: 390/40 nm; Green channel: 482/18 nm; Red channel: 586/15 nm
Emission: Blue channel: 446/33 nm; Green channel: 532/59 nm; Red channel: 646/68 nm
Captured Images: 16-bit monochrome, TIFF, PNG, JPG, or BMP (1296 × 964 pixels)
LCD display: 15-inch color; display resolution 1366 x 768 pixels; image resolution 1296 x 964 pixels; adjustable tilt
Dimensions: (W x H x D): 15.9" x 21.1 x 13.9" / 40.4 cm x 53.6 cm x 35.3 cm; 28 lbs / 12.7 kg