Shop All Sequencing & Genetic Analyzer Instruments & Accessories

Ion GeneStudio™ S5 Prime System (Ion Torrent™)

The Ion GeneStudio S5 Prime System is a semiconductor-based next-generation sequencing (NGS) system that enables simple targeted sequencing workflows. For core and service labs requiring maximum throughput and rapid turnaround time from a benchtop NGS system, the Ion GeneStudio S5 Prime System enables unparalleled breadth and depth, from large panels or exomes to clinical oncology research focused on low allele frequency applications. With cartridge-based reagents, the system is simple to use and offers scalability and flexibility. It uses Ion 5 Series chips to support a broad range of high-throughput sequencing for clinical research and research applications from microbial genomes and gene panels to exomes and transcriptomes.

Key features:
• Select the chip (Ion 510–550 chip) that fits your application and throughput needs to achieve from 2–130 million reads per run
• Reduce setup time and complexity with cartridge-based plug-and-play reagents
• Complete run and analysis in hours and move forward with your experiments

The Ion GeneStudio S5 Series
The Ion GeneStudio S5 Series sequencers share the same foundational technology and fluidic architecture across all three instruments: the Ion GeneStudio S5 System, the Ion GeneStudio S5 Plus System, and this Ion GeneStudio S5 Prime System. The primary difference across the three instruments is on-sequencer analysis time.

Speed
The Ion GeneStudio S5 Series leverages the speed of semiconductor sequencing to enable the production of high quality sequencing data in a few hours and enables you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time when paired with the Ion Chef System.

Simplicity
With single-day installation, a straightforward user interface, and cartridge-based reagents, the Ion GeneStudio S5 Series sequencers are easy to use. Combined with Ion AmpliSeq technology for target selection, the Ion Chef System for automated library and template preparation, and Ion Reporter Software for automated variant annotation, targeted sequencing is simpler than ever.

Small sample input
Low input DNA from challenging samples types such as formalin-fixed paraffin-embedded (FFPE) tissue, retrospective samples from fine needle aspirates, and cell-free DNA extracted from blood (cfDNA) can be difficult to sequence on competitor next-generation sequencers. However, with Ion AmpliSeq technology and the Ion GeneStudio S5 Series, you can use as little as 1 ng input DNA or RNA.

Scalability
Why buy multiple systems for your lab when you can run all of your targeted sequencing or microbial applications on a single next-generation sequencer? The Ion 5 Series chips that run on the Ion GeneStudio S5 Series provide several throughput options, so your lab has the flexibility to scale from small to large projects, enabling multiple targeted sequencing applications on a single system.

Simple analysis and storage solutions
Torrent Suite Software and Ion Reporter Software make NGS easy for beginners and experts alike. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Ion Reporter Software (Thermo Fisher Cloud or local options available based on your needs).

Services and support
With more than 2,000 field personnel, Thermo Fisher Scientific has the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so you can be confident that we will be there when and where you need us most.

Service and support plans—comprehensive plans to maximize instrument performance and ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data

5500 W FlowChip V2 (Applied Biosystems™)

The 5500 W FlowChip V2 is a microfluidic glass device with primers on the surface that enable amplification of library template onto the FlowChip for ligation sequencing on the 5500 W Series genetic analyzers. The 5500 W FlowChip V2 is specially designed with precisely cut lanes. Individual library samples can be deposited for amplification in each lane of the FlowChip. Sequencing reagents are delivered to each lane separately, enabling consumption of sequencing reagents for just the number of lanes used for sequencing.

The 5500 W FlowChip V2 is notched to set the orientation. Each 5500 W FlowChip V2 kit contains one 5500 W FlowChip V2 and a deposition cassette that aids in depositing sample libraries. The 5500 W FlowChip Prep Pack (available separately) contains reagents for depositing library template onto the 5500 W FlowChip V2.

Air Filter, 310 (10 x 20 x 7/8 inches) (Applied Biosystems™)

This is an air filter (10 x 20 x 7⁄9 inches) for the 310 Genetic Analyzer.

Use with the 310 Genetic Analyzer with Windows® OS.

For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

3730xl DNA Analyzer (Applied Biosystems™)

The 96-capillary 3730xl DNA Analyzer is the Gold Standard for high throughput genetic analysis. Use this for DNA fragment analysis applications such as microsatellites, AFLP, SNP analysis, mutation detection and traditional DNA sequencing. Get the highest quality data at a low cost per sample.
• Higher optical sensitivity and advanced polymers enable you to obtain higher-quality sequencing data for less.
• Multiple automation features decrease costly human errors.
• Optimized polymers increase your productivity without compromising your results.
• Perform a wide variety of sequencing and fragment analysis applications including resequencing, microsatellite analysis, AFLP, LOH, SSCP, SNP screening and SNP validation.

Large-Scale DNA Analysis on a Small-Scale Budget
By combining advances in automation with innovative optics and proprietary reagents to increase throughput, yield high-quality data, and minimize reagent consumption, the 3730xl Analyzer provides your laboratory and production facility with faster, better, cheaper analysis.

Streamline Your Workflow
The 3730xl DNA Analyzer system is engineered for highly reliable, unattended operation of up to 48 hours (applies to modules with run times longer than 30 minutes). To minimize the need for operator intervention and decrease the risk of human error, automation features include an integrated plate stacker, internal bar code reader, and onboard polymer delivery system.

Increase Productivity
The high signal-to-noise ratio ensures you get high-quality data – even when you use low-concentration samples and reagents. Labor-saving automation features minimize hands-on time and enable you to analyze more data more efficiently.

Get the Highest-Quality Sequencing and Genotyping Data
The enhanced optical design provides a higher signal-to-noise ratio and a more uniform signal profile across the array. This design, combined with our new, advanced polymer, enables the longest read lengths of any available system, and provides enhanced color balance for streamlined genotyping sample handling. In addition, exceptional sensitivity enables higher success rates across a wide range of sample template types and concentrations.

One Instrument, Multiple Applications
With the 3730xl DNA Analyzer, you get the highest-quality data from a wide array of applications. In addition to being ideal for high-throughput sequencing, the analyzer's optimized application assays, instrument, and analysis software also provide a complete solution for genotyping and resequencing.

Integrated Data Analysis Tools Reduce Time-to-Results
The 3730xl DNA Analyzer software suite allows you to generate more meaningful data with less work. This system's labor-saving software suite includes:
• Data Collection (supplied with the instrument) – Manages your instrument setup, controls instrument operations, allows real-time data visualization, and performs diagnostics.
• Sequencing Analysis Software – Designed to base-call; assign quality values; trim, display, edit and print DNA sequencing data using the KB basecaller
• Seqscape® – Provides everything you need to perform resequencing applications such as VariantSEQr™ Resequencing System
• GeneMapper® – Enables configurable, automated allele calling; a plus for high-throughput genotyping and includes tools for SNPlex™ data analysis

New features include:
• Auto-analysis with GeneMapper® and SeqScape®
• Flexibility to use any choice in dye set option
• Tools to assist with regulatory and compliance requirements (In the United States, this assists with FDA 21CFR part 11).
• Additional optimized run modules covering more applications
• Support for fragment analysis applications on the 96-capillary array

The instrument comes with a one year limited warranty on parts and labor.

For Research Use Only. Not for use in diagnostics procedures.

Plate Base, 96 well (Applied Biosystems™)

This is a spare part for use with the 3100, 3100-Avant™, 3130, and 3130xl Genetic Analzyers.

For Research Use Only. Not for use in diagnostics procedures.

Upgrade for 3730-3730xl, 50 cm array (Applied Biosystems™)

This is an accessory for the 3730⁄3730xl DNA Analyzer.

For Research Use Only. Not for use in diagnostics procedures.

3500 Genetic Analyzer for Resequencing & Fragment Analysis (Applied Biosystems™)

The 3500 Genetic Analyzer is an 8-capillary sequencing instrument specifically designed to support the demanding performance needs of validated and process controlled environments, while retaining the unsurpassed application versatility that life science researchers expect.

This package includes an 8-capillary instrument, 3500 Series Data Collection Software, a Dell Workstation and monitor, as well as reagent kits for system qualification and secondary analysis software. The 3500 Series Data Collection Software supports sequencing and fragment analysis, and integrates seamlessly with downstream software for secondary analysis of genetic data. This package includes such secondary software: GeneMapper® software for fragment analysis and software for resequencing applications.

Features include:

• An 8 capillary system that can easily be upgraded to a 24-capillary system when you’re ready.
• Single-line, 505 nm, solid-state, long-life laser that utilizes a standard power supply and requires no heat-removal ducting
• Powerful, integrated data collection and primary analysis software provides real-time assessment of data quality
• Radio frequency identification (RFID) technology tracks key consumables data and records administrative information
• Advanced multiplexing capabilities for DNA fragment analysis with up to six unique dyes
• Unrivaled application flexibility—one array and one polymer are used for most applications.
• Simple setup, operation and maintenance

Accurate Reliable Data Quality
The 3500 series systems significantly improves signal uniformity from instrument-to-instrument, run-to-run, and capillary-to-capillary. With a combination of intelligent hardware, powerful new algorithm and reagent combinations, these methods provide major reduction in the range of signal peak heights obtained across multiple 3500 series instruments (see figure).

Improved Sizing Precision
New thermal sub-system design gives enhanced performance in demanding fragment applications enabling improved sizing precision versus previous generations of capillary electrophoresis platforms.

Ready to Use Consumables With RFID Tags
The 3500 series introduces ready-to-use consumables with pre-packaged polymer pouches, cathode and anode buffer containers, and easy-to-install capillary arrays. Each of these consumables is integrated with RFID tags that enable viewing, tracking, and reporting of critical information about reagents and consumables including usage, lot number, part number, expiry date, and on-instrument lifetime within the 3500 Series Data Collection Software.

Easy to Use Data Collection Software
3500 Series Data Collection software breaks new ground in user-friendly navigation with an intuitive dashboard design, highly visible buttons for common operations, easy-to-read graphical displays to monitor the state of consumables and handy maintenance scheduling calendar functionality. New functionality includes simplified plate set-up and built-in primary analysis with quality control, so you can make decisions about the quality of data as it is produced on the instrument without the need to transfer output files into secondary analysis software packages.

3730xl DNA Analyzer (factory refurbished) (Applied Biosystems™)

The 96-capillary 3730xl DNA Analyzer is the Gold Standard for high throughput genetic analysis. Use this for DNA fragment analysis applications such as microsatellites, AFLP, SNP analysis, mutation detection and traditional DNA sequencing. Get the highest quality data at a low cost per sample. This instrument is refurbished by the original manufacturer to meet both manufacturing and product specifications. This system includes the refurbished instrument, new Windows computer, Data Collection software, choice of one analysis software package, installation by an Applied Biosystems “5-Step Certified" Field Service Engineer, chemistry kit, training, new parts and a one year warranty. Availability may be limited.

• Higher optical sensitivity and advanced polymers enable you to obtain higher-quality sequencing data for less.
• Multiple automation features decrease costly human errors.
• Optimized polymers increase your productivity without compromising your results.
• Perform a wide variety of sequencing and fragment analysis applications including resequencing, microsatellite analysis, AFLP, LOH, SSCP, SNP screening and SNP validation.

Large-Scale DNA Analysis on a Small-Scale Budget
By combining advances in automation with innovative optics and proprietary reagents to increase throughput, yield high-quality data, and minimize reagent consumption, the 3730xl Analyzer provides your laboratory and production facility with faster, better, cheaper analysis.

Streamline Your Workflow
The 3730xl DNA Analyzer system is engineered for highly reliable, unattended operation of up to 48 hours (applies to modules with run times longer than 30 minutes). To minimize the need for operator intervention and decrease the risk of human error, automation features include an integrated plate stacker, internal bar code reader, and onboard polymer delivery system.

Increase Productivity
The high signal-to-noise ratio ensures you get high-quality data – even when you use low-concentration samples and reagents. Labor-saving automation features minimize hands-on time and enable you to analyze more data more efficiently.

Get the Highest-Quality Sequencing and Genotyping Data
The enhanced optical design provides a higher signal-to-noise ratio and a more uniform signal profile across the array. This design, combined with our new, advanced polymer, enables the longest read lengths of any available system, and provides enhanced color balance for streamlined genotyping sample handling. In addition, exceptional sensitivity enables higher success rates across a wide range of sample template types and concentrations.

One Instrument, Multiple Applications
With the 3730xl DNA Analyzer, you get the highest-quality data from a wide array of applications. In addition to being ideal for high-throughput sequencing, the analyzer's optimized application assays, instrument, and analysis software also provide a complete solution for genotyping and resequencing.

Integrated Data Analysis Tools Reduce Time-to-Results
The 3730xl DNA Analyzer software suite allows you to generate more meaningful data with less work. This system's labor-saving software suite includes:
• Data Collection (supplied with the instrument): Manages your instrument setup, controls instrument operations, allows real-time data visualization, and performs diagnostics.
• Sequencing Analysis Software: Designed to base-call; assign quality values; trim, display, edit and print DNA sequencing data using the KB basecaller.
• Seqscape®: Provides everything you need to perform resequencing applications such as VariantSEQr™ Resequencing System.
• GeneMapper®: Enables configurable, automated allele calling – a plus for high-throughput genotyping and includes tools for SNPlex™ data analysis

New features include:
• Auto-analysis with GeneMapper® and SeqScape®
• Flexibility to use any choice in dye set option
• Tools to assist with regulatory and compliance requirements (In the United States, this assists with FDA 21CFR part 11).
• Additional optimized run modules covering more applications
• Support for fragment analysis applications on the 96-capillary array

The instrument comes with a one year limited warranty on parts and labor.

For Research Use Only. Not for use in diagnostics procedures.

Plate Retainer, 384 well (Applied Biosystems™)

This is a spare part for use with the 3100, 3100-Avant™, 3130, and 3130xl Genetic Analzyers.

For Research Use Only. Not for use in diagnostics procedures.

Reservoir Septa (Applied Biosystems™)

This is a Reservoir Septa for ABI PRISM® 3100 Genetic Analyzer and ABI PRISM® 3100-Avant™ Genetic Analyzer.

For Research Use Only. Not for use in diagnostics procedures.

3500xL Genetic Analyzer for Protein Quality Analysis (Applied Biosystems™)

The 3500xL Genetic Analyzer for Protein Quality Analysis is a capillary electrophoresis instrument with a 24-capillary array specifically designed to support the demanding performance needs of biopharmaceutical screening and quality control environments, while retaining the unsurpassed application versatility appreciated by scientists working in analytical and process development environments. The instrument enables parallel analysis of 24 samples without compromising on the run time per sample, thereby enabling high throughput analysis with high quality data.

This system includes a 24-capillary instrument, a Dell Workstation and monitor, as well as reagent kits for system qualification. For a system that includes GlycanAssure™ Acquisition and Analysis Software, please see Cat. No. A30887.

Features include:
• A 24-capillary system for high throughput analysis
• Single-line, 505 nm, solid-state, long-life laser that utilizes a standard power supply and requires no heat-removal
• Radio frequency identification (RFID) technology that tracks key consumables data and records administrative information
• Advanced multiplexing capabilities for glycan analysis with up to six unique dyes
• Unrivaled application flexibility—one array and one polymer are used for most applications
• Simple setup, operation, and maintenance

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Accurate, precise, and reliable data quality
The 3500 Series systems significantly improve signal uniformity from instrument-to-instrument, run-to-run, and capillary array-to-capillary array. The system provides accurate, reproducible, and precise relative quantitation of glycan levels.

Ready-to-use consumables with RFID tags
The 3500 Series systems introduce ready-to-use consumables with pre-packaged polymer pouches, cathode and anode buffer containers, and easy-to-install capillary arrays. Each of these consumables is integrated with RFID tags that enable viewing, tracking, and reporting of critical information about reagents and consumables, including usage, lot number, part number, expiry date, and on-instrument lifetime within the Glycan Assure data acquisition software.

Additional products
The following products are required for use with this system:
A31278: Anode Buffer Container (ABC) for 3500 Series for Protein Quality Analysis
A31279: Cathode Buffer Container (CBC) for 3500 Series for Protein Quality Analysis
A30936: POP-7™ for Protein Quality Analysis (384 samples)

Pouch Cap for Polymer Pouch (Applied Biosystems™)

This is a cap for use with POP-4™, POP-6™, and POP-7™ polymer pouches.

For Research Use Only. Not for use in diagnostics procedures.

3500xL Genetic Analyzer for Resequencing & Fragment Analysis (Applied Biosystems™)

The 3500xL 24-capillary platform can run a wide variety of applications, including de novo sequencing and resequencing (mutational profiling), as well as microsatellite analysis, MLPA™, LOH, MLST, AFLP® and SNP validation or screening. The majority of applications can be run on a single polymer and capillary array.

This package includes a 24-capillary instrument, 3500 Series Data Collection Software, a Dell Workstation and monitor, as well as reagent kits for system qualification and secondary analysis software. The 3500 Series Data Collection Software supports sequencing and fragment analysis, and integrates seamlessly with downstream software for secondary analysis of genetic data. This package includes such secondary software: GeneMapper® software for fragment analysis and software for resequencing applications.

Features include:

• An 8 capillary system that can easily be upgraded to a 24-capillary system when you’re ready.
• Single-line, 505 nm, solid-state, long-life laser that utilizes a standard power supply and requires no heat-removal ducting
• Powerful, integrated data collection and primary analysis software provides real-time assessment of data quality
• Radio frequency identification (RFID) technology tracks key consumables data and records administrative information
• Advanced multiplexing capabilities for DNA fragment analysis with up to six unique dyes
• Unrivaled application flexibility—one array and one polymer are used for most applications.
• Simple setup, operation and maintenance

Accurate Reliable Data Quality
The 3500 series systems significantly improves signal uniformity from instrument-to-instrument, run-to-run, and capillary-to-capillary. With a combination of intelligent hardware, powerful new algorithm and reagent combinations, these methods provide major reduction in the range of signal peak heights obtained across multiple 3500 series instruments (see figure).

Improved Sizing Precision
New thermal sub-system design gives enhanced performance in demanding fragment applications enabling improved sizing precision versus previous generations of capillary electrophoresis platforms.

Ready to Use Consumables With RFID Tags
The 3500 series introduces ready-to-use consumables with pre-packaged polymer pouches, cathode and anode buffer containers, and easy-to-install capillary arrays. Each of these consumables is integrated with RFID tags that enable viewing, tracking, and reporting of critical information about reagents and consumables including usage, lot number, part number, expiry date, and on-instrument lifetime within the 3500 Series Data Collection Software.

Easy to Use Data Collection Software
3500 Series Data Collection software breaks new ground in user-friendly navigation with an intuitive dashboard design, highly visible buttons for common operations, easy-to-read graphical displays to monitor the state of consumables and handy maintenance scheduling calendar functionality. New functionality includes simplified plate set-up and built-in primary analysis with quality control, so you can make decisions about the quality of data as it is produced on the instrument without the need to transfer output files into secondary analysis software packages.

CBL, 16FT Serial DB9 TO Serial DIN8 (Applied Biosystems™)

Each package contains 16 ft of Serial DB9 to Serial DIN9 cable for the 310 Genetic Analyzer.

For Research Use Only. Not for use in diagnostics procedures.

Replacement Lamp for 5500 series Genetic Analyzers (Applied Biosystems™)

This is replacement lamp for the Applied Biosystems® 5500, 5500xl, and 5500xl-W genetic analysis systems.