Shop All Sequencing & Genetic Analyzer Instruments & Accessories

Septa for 3500xL Genetic Analyzer, 384 well (Applied Biosystems™)

These septa for 384-well plates are for use with the 3500xL Genetic Analyzer.

For Research Use Only. Not for use in diagnostics procedures.

Ion S5™ System (Ion Torrent™)

The Ion S5™ next-generation sequencing system enables a simple targeted sequencing workflow for your lab at an affordable price, without compromising on performance or reliability. The Ion S5 System leverages the speed of semiconductor sequencing with impressive on-board computing power, to enable the production of high quality sequencing data in as little as 2.5 hours and enable you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time on the Ion Chef™ System and the Ion S5 System. The Ion S5 System is simple to use with cartridge-based reagents and offers superior scalability and flexibility to support a broad range of high throughput sequencing applications, from microbial genomes and gene panels to exomes and transcriptomes, using our 5 Series chips.

Speed
Some research decisions can’t wait. A few hours could make all the difference in your quest for the right answer.With other light-based sequencers you could wait almost 60 hours for results. With the Ion S5 System you get results in as little as 24 hours (with a 2.5-4 hour sequencer run time and overnight Ion Chef System run).

Simplicity
With single-day installation, a straightforward user interface, and cartridge-loaded reagents, the Ion S5 System is easy to use. Beyond this, the system is part of a workflow that allows you to go from DNA to data with only 45 minutes of total hands-on time on the Ion Chef System and the Ion S5 System, significantly less than other targeted sequencing solutions that require as much as 2.5 hours of hands-on time. Combined with Ion AmpliSeq™ technology for target selection, the Ion Chef™ System for automated library and template preparation, and Ion Reporter™ Software for automated variant annotation, targeted sequencing becomes simpler than ever.

Small sample input
Low input DNA for challenging samples types, such as formalin-fixed paraffin-embedded (FFPE) tissue, retrospective samples from fine needle aspirates, and cell-free DNA extracted from blood (cfDNA) can be difficult to sequence on competititor next-generation sequencers. However, with Ion AmpliSeq technology and the Ion S5 Sequencer, you can use as little as 10 ng input DNA or RNA.

Scalability
Why buy multiple systems for your lab when you can run all of your targeted sequencing or microbial applications on a single next-generation sequencer? The Ion S5 System has a modular build, so your lab has the flexibility to do multiple targeted sequencing applications on a single system.

Simple analysis and storage solutions
Whether you are new to next-generation sequencing or an expert user, Torrent Suite™ Software and Ion Reporter™ Software make it easy for you to get started with next-generation sequencing. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Ion Reporter Software (Cloud or local options available based on your needs).

Services and support
With more than 2,000 field personnel, Thermo Fisher Scientific has the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so you can be confident that we will be there when and where you need us most.

Service and support plans—comprehensive plans to maximize instrument performance and ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data

Septa for 3500/3500xL Genetic Analyzers, 96 well (Applied Biosystems™)

These septa for 96 well plates are designed and validated for use with the 3500 series Genetic Analyzers.

For Research Use Only. Not for use in diagnostics procedures.

Plate Base (septa seal), 96 well (Applied Biosystems™)

This is a 96-well Plate Base (Septa Seal) for use with Applied Biosystems® 3730 and 3730xl DNA Analyzers.

For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

Anode Buffer Reservoir Jar (Applied Biosystems™)

This Buffer Reservoir is for use with the 3100-Avant™ Genetic Analyzer. It attaches to the lower polymer block, holding the anodic buffer.

For Research Use Only. Not for use in diagnostics procedures.

Syringe Plug, 310 (1/4-28 TFE) (for the 310 Genetic Analyzer) (Applied Biosystems™)

This is a 1⁄4-28 TFE syringe plug fitting for the 310 Genetic Analyzer.

Use with the 310 Genetic Analyzer with Windows® OS.

For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

SOLiD™ EZ Bead™ Enricher Accessories Kit (Applied Biosystems™)

This accessories kit contains all customized accessories (tubing, containers, funnels, pouches, filters) for performing E-series scale reactions using the SOLiD™ EZ Bead™ Enricher.

For Research Use Only. Not for use in diagnostics procedures.

Plate Base for 3730 (septa seal), Fast (0.1 mL), 96 well (Applied Biosystems™)

This is a 96-well Plate Base (Septa Seal) for use ONLY with FAST 0.1 ml sample plates on Applied Biosystems 3730 and 3730xl DNA Analyzers.

For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

Ion Personal Genome Machine™ (PGM™) System (Ion Torrent™)

The Ion Personal Genome Machine (PGM) System combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data, democratizing sequencing and making it accessible to your lab. This established system leverages the exponential improvements in the semiconductor industry (known as Moore’s Law) to provide scalability and flexibility for various applications. The Ion PGM System uses natural sequencing chemistry, which eliminates the need for expensive optics and reduces complex chemistries to measure natural DNA extension. The system leverages direct, real-time sequencing detection, providing sequencing results typically in 3–7 hours.

Affordable sequencing for small genomes and targeted panels
Other sequencing technologies rely on optical systems as bridges between chemical and digital sequence information. These systems typically entail significant additional costs; the elimination of the optical system by the Ion PGM System reduces these costs. With its small benchtop footprint, weight of about 65 lbs (30 kg), low-cost sequencing reagents, and simple touchscreen user interface, the Ion PGM System brings next-generation sequencing to your lab. Coupled with the Torrent Suite Software, the Ion PGM System performs preliminary reference genome alignment and outputs data in BAM format for easy downstream analysis with optional third party analysis tools. It can also provide access to a web portal for data review and sharing.

More information on the Ion Torrent Server >

Ion power: PostLight sequencing produces bits from bases
The sequencing technology underlying the Ion PGM System exploits a well-characterized biochemical process: when a polymerase incorporates a nucleotide into the growing strand of DNA, a hydrogen ion (H+) is released as a byproduct. This hydrogen ion carries a charge which the Ion PGM chip—essentially the world's smallest solid-state pH meter—can detect. As the sequencer floods the chip with one nucleotide after another, any nucleotide added to a DNA template will be detected as a voltage change, and the Ion PGM System will call the base. If a nucleotide is not a match for a particular template, no voltage change will be detected and no base will be called for that template.

Next-generation sequencing on your bench
A principal component of the Ion PGM System is the sequencing chip. This microprocessor chip incorporates an extremely dense array of >1 million micro-machined wells married to our proprietary ion sensor. Each well contains a different DNA template, allowing massively parallel sequencing. The chips can scale in density for specific applications from targeted panels to small genomes.

The right tool to get results easily, reliably, and quickly
Since it detects nucleotide incorporation without the use of light, the Ion PGM System uses the simplest sequencing chemistry possible: natural nucleotides. There is no need for expensive and error-prone modified bases, enzymatic cascades, chemiluminescence, or fluorescence. Direct detection also means the incorporation of each nucleotide is recorded in seconds. As a result, the Ion PGM System runs finish within hours rather than days.

Services and support
Service and support plans—comprehensive plans to maximize instrument performance and ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data

For a more simplified next-generation sequencing workflow, see the Ion S5 System.

Learn more about the Ion PGM sequencing chips >

Ion S5™ XL System (Ion Torrent™)

The Ion S5™ XL next-generation sequencing system enables a simple targeted sequencing workflow for your lab with reliable performance and industry-leading speed. The Ion S5 XL System leverages the speed of semiconductor sequencing with impressive computing power found both on-board and in the included Torrent Server, to produce high quality sequencing data in as little as 2.5 hours and enable you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time on the Ion Chef™ System and the Ion S5 XL System. The Ion S5 XL System is simple to use with cartridge-based reagents and offers superior scalability and flexibility to support a broad range of high throughput sequencing applications, from microbial genomes and gene panels to exomes and transcriptomes, using our 5 Series chips.

Speed
Some research decisions can’t wait. A few hours could make all the difference in your quest for the right answer.With other light-based sequencers you could wait almost 60 hours for results. With the Ion S5 XL System you get results in as little as 24 hours (with a 2.5-4 hour sequencer run time and overnight Ion Chef System run)—the fastest turnaround of any next-generation sequencer currently on the market.

Simplicity
With single-day installation, a straightforward user interface, and cartridge-loaded reagents, the Ion S5 XL System is easy to use. Beyond this, the system is part of a workflow that allows you to go from DNA to data with only 45 minutes of total hands-on time on the Ion Chef System and the Ion S5 XL System, significantly less than other targeted sequencing solutions that require as much as 2.5 hours of hands-on time. Combined with Ion AmpliSeq™ technology for target selection, the Ion Chef™ System for automated library and template preparation, and Ion Reporter™ Software for automated variant annotation, targeted sequencing becomes simpler than ever.

Small sample input
Low input DNA for challenging samples types, such as formalin-fixed paraffin-embedded (FFPE) tissue, retrospective samples from fine needle aspirates, and cell-free DNA extracted from blood (cfDNA) can be difficult to sequence on competitor next-generation sequencers. However, with Ion AmpliSeq technology and the Ion S5 XL Sequencer, you can use as little as 10 ng input DNA or RNA.

Scalability
Why buy multiple systems for your lab when you can run all your targeted sequencing or microbial research applications on a single next-generation sequencer? The Ion S5 XL System has a modular build, so your lab has the flexibility to do multiple targeted sequencing applications on a single system.

Simple analysis and storage solutions
Whether you are new to next-generation sequencing or an expert user, Torrent Suite™ Software and Ion Reporter™ Software make it easy for you to get started with next-generation sequencing. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Ion Reporter Software (Cloud or local options available based on your needs).

Services and support
With more than 2,000 field personnel, Thermo Fisher Scientific has the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so you can be confident that we will be there when and where you need us most.

Service and support plans—comprehensive plans to maximize instrument performance and ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data

Pouch Cap for Polymer Pouch (Applied Biosystems™)

This is a cap for use with POP-4™, POP-6™, and POP-7™ polymer pouches.

For Research Use Only. Not for use in diagnostics procedures.

Plate Base (septa seal) for 3730/3730xl, 384 well (Applied Biosystems™)

This is a 384-well Plate Base (Septa Seal) for use with Applied Biosystems® 3730 and 3730xl DNA Analyzers.

For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

Covaris™ M220 miniTUBE Prep Station & Stand (Ion Torrent™)

The Covaris® M220 miniTUBE Prep Station enables the easy loading of sample into clear, blue, or red miniTUBEs. A tilted stand is included that has been designed to help recover the entire sample from the miniTUBE. Each package contains 1 preparation station.

IKA™ Template Preparation Tubes (Applied Biosystems™)

These customized tubes and caps are for use with the ULTRA-TURRAX® Tube Drive from IKA® for emulsion PCR for use with the SOLiD system and 5500 series Genetic Analyzers

For Research Use Only. Not for use in diagnostics procedures.

Air Filter, 310 (10 x 20 x 7/8 inches) (Applied Biosystems™)

This is an air filter (10 x 20 x 7⁄9 inches) for the 310 Genetic Analyzer.

Use with the 310 Genetic Analyzer with Windows® OS.

For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.