Shop All Sequencing & Genetic Analyzer Instruments

3500xL Dx Genetic Analyzer CS2 (Applied Biosystems™)

The 3500 Dx Genetic Analyzer CS2 is the latest addition to our family of Applied Biosystems® genetic analyzers based on capillary electrophoresis. The 3500 Dx Genetic Analyzer CS2 is an IVD-labeled instrument, making it the first Sanger sequencing platform cleared for sequencing analysis of DNA.

Confidence in Your Results
• The 3500 Dx Genetic Analyzer CS2 is an IVD-labeled platform for Sequencing-Based Typing using SeCore® HLA typing kits. Sanger sequencing is known as the "gold-standard" for its accuracy, reliability, and ease of use. It is also used for confirmatory sequencing by clinical labs.
• High accuracy: 99% concordance as shown in clinical trials using SeCore® HLA typing kits
• Proven through decades of results—including sequencing of the first human genome—Applied Biosystems® genetic analysis systems are trusted standards for Sanger sequencing.

You can now feel even more comfortable adopting the 3500 Dx Genetic Analyzer CS2 platform for the development of assays for FDA submission.

Simplicity and Efficiency
• Reduced instrument hands-on time with simplified installation and removal of consumables and accessories
• Controlled and efficient run setup with intuitive user interface, preconfigured plate templates, and software-controlled functions (plate setup, data collection, analysis)
• Instrument run-times as short as 1 hour; sample-to-result in as little as 1.5 days
• Maintenance calendar with programmable prompts and service history
• Security and electronic signature, RFID (radio frequency identification) tracking of consumables, built-in quality controls, and real-time data quality evaluation

The 3500 Dx Genetic Analyzer CS2 is a partner in your laboratory, making it easy for you to comply with various industry standards and simplifying the training of new users.

Flexibility
• Collect data in either IVD (diagnostic for HLA typing) or RUO mode
• Develop other applications in RUO mode, including de novo sequencing and re-sequencing, as well as fragment analysis applications such as microsatellite analysis, MLPA®, LOH, MLST, and SNP confirmation or screening
• Partner with us to develop assays for FDA submission
• Different configurations to meet your throughput needs: 24-capillary (3500xL Dx) and 8-capillary (3500 Dx) versions

The 3500 Dx Genetic Analyzer CS2 is a trusted capillary electrophoresis-based sequencing platform for development of your new assays. Capillary electrophoresis-based applications are supported by a large number of publications over the many years that these applications have been used successfully in laboratory testing.

IVD-labeled Accessories and Consumables
The purchase of a 3500 Dx Genetic Analyzer CS2 includes a computer system and associated Data Collection software, as well as an installation kit containing the initial set of accessories and reagents needed to start using the instrument right away. The 3500 Dx Genetic Analyzer CS2 installation includes a full install qualification and operational qualification, as well as instrument training to introduce you to your new genetic analyzer.

The 3500 Dx is backed by a comprehensive Service & Support program with options to purchase additional services depending upon your laboratory maintenance and audit requirements.

Intended Use
The Applied Biosystems® 3500 Dx and 3500xL Dx Genetic Analyzers CS2 with 3500 Dx Series Software 2011 (v1) are in vitro diagnostic devices intended for the sequencing (detection and identification) of fluorescently labeled DNA by capillary electrophoresis.

The Applied Biosystems® 3500 Dx/3500xL Dx Genetic Analyzers CS2 with 3500 Dx Series Software 2011 (v1) are indicated for use with FDA-cleared or approved sequencing assays specifying their use and only by technologists trained in laboratory techniques, procedures, and use of the analyzer.

Note: The 3500 Dx Genetic Analyzer CS2 data collection software uses Windows 7 SP0 operating system. This makes the currently available RUO secondary analysis software incompatible for use on the same system. A separate computer is required to do secondary analysis if operating in RUO mode.

Ion GeneStudio™ S5 Plus System for Agrigenomics (Ion Torrent™)

The Ion GeneStudio S5 Plus System is a semiconductor-based next-generation sequencing (NGS) system that enables simple targeted sequencing workflows. From genes to exomes, the Ion GeneStudio S5 Plus System is designed to enable flexibility to help labs manage small and large projects across multiple applications. With cartridge-based reagents, the system is simple to use and offers scalability and flexibility. It uses Ion 5 Series chips to support a broad range of high-throughput sequencing for clinical research and research applications from microbial genomes and gene panels to exomes and transcriptomes.

Key features:
• Select the chip (Ion 510–550 chip) that fits your application and throughput needs to achieve from 2–130 million reads per run
• Reduce setup time and complexity with cartridge-based plug-and-play reagents
• Complete run and analysis in hours and move forward with your experiments

The Ion GeneStudio S5 Series
The Ion GeneStudio S5 Series sequencers share the same foundational technology and fluidic architecture across all three instruments: the Ion GeneStudio S5 System, this Ion GeneStudio S5 Plus System, and Ion GeneStudio S5 Prime System. The primary difference across the three instruments is on-sequencer analysis time.

Speed
The Ion GeneStudio S5 Series leverages the speed of semiconductor sequencing to enable the production of high quality sequencing data in a few hours and enables you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time when paired with the Ion Chef System.

Simplicity
With single-day installation, a straightforward user interface, and cartridge-based reagents, the Ion GeneStudio S5 Series sequencers are easy to use. Combined with Ion AmpliSeq technology for target selection, the Ion Chef System for automated library and template preparation, and Ion Reporter Software for automated variant annotation, targeted sequencing is simpler than ever.

Small sample input
Low input DNA from challenging samples types such as formalin-fixed paraffin-embedded (FFPE) tissue, retrospective samples from fine needle aspirates, and cell-free DNA extracted from blood (cfDNA) can be difficult to sequence on competitor next-generation sequencers. However, with Ion AmpliSeq technology and the Ion GeneStudio S5 Series, you can use as little as 1 ng input DNA or RNA.

Scalability
Why buy multiple systems for your lab when you can run all of your targeted sequencing or microbial applications on a single next-generation sequencer? The Ion 5 Series chips that run on the Ion GeneStudio S5 Series provide several throughput options, so your lab has the flexibility to scale from small to large projects, enabling multiple targeted sequencing applications on a single system.

Simple analysis and storage solutions
Torrent Suite Software and Ion Reporter Software make NGS easy for beginners and experts alike. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Ion Reporter Software (Thermo Fisher Cloud or local options available based on your needs).

Services and support
With more than 2,000 field personnel, Thermo Fisher Scientific has the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so you can be confident that we will be there when and where you need us most.

Service and support plans—comprehensive plans to maximize instrument performance and ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data

3500 Dx Genetic Analyzer CS2 (Applied Biosystems™)

The 3500 Dx Genetic Analyzer CS2 is the latest addition to our family of Applied Biosystems® genetic analyzers based on capillary electrophoresis. The 3500 Dx Genetic Analyzer CS2 is an IVD-labeled instrument, making it the first Sanger sequencing platform cleared for sequencing analysis of DNA.

Confidence in Your Results
• The 3500 Dx Genetic Analyzer CS2 is an IVD-labeled platform for Sequencing-Based Typing using SeCore® HLA typing kits. Sanger sequencing is known as the "gold-standard" for its accuracy, reliability, and ease of use. It is also used for confirmatory sequencing by clinical labs.
• High accuracy: 99% concordance as shown in clinical trials using SeCore® HLA typing kits
• Proven through decades of results—including sequencing of the first human genome—Applied Biosystems® genetic analysis systems are trusted standards for Sanger sequencing.

You can now feel even more comfortable adopting the 3500 Dx Genetic Analyzer CS2 platform for the development of assays for FDA submission.

Simplicity and Efficiency
• Reduced instrument hands-on time with simplified installation and removal of consumables and accessories
• Controlled and efficient run setup with intuitive user interface, preconfigured plate templates, and software-controlled functions (plate setup, data collection, analysis)
• Instrument run-times as short as 1 hour; sample-to-result in as little as 1.5 days
• Maintenance calendar with programmable prompts and service history
• Security and electronic signature, RFID (radio frequency identification) tracking of consumables, built-in quality controls, and real-time data quality evaluation

The 3500 Dx Genetic Analyzer CS2 is a partner in your laboratory, making it easy for you to comply with various industry standards and simplifying the training of new users.

Flexibility
• Collect data in either IVD (diagnostic for HLA typing) or RUO mode
• Develop other applications in RUO mode, including de novo sequencing and re-sequencing, as well as fragment analysis applications such as microsatellite analysis, MLPA®, LOH, MLST, and SNP confirmation or screening
• Partner with us to develop assays for FDA submission
• Different configurations to meet your throughput needs: 8-capillary (3500 Dx) and 24-capillary (3500xL Dx) versions

The 3500 Dx Genetic Analyzer CS2 is a trusted capillary electrophoresis-based sequencing platform for development of your new assays. Capillary electrophoresis-based applications are supported by a large number of publications over the many years that these applications have been used successfully in laboratory testing.

IVD-labeled Accessories and Consumables
The purchase of a 3500 Dx Genetic Analyzer CS2 includes a computer system and associated Data Collection software, as well as an installation kit containing the initial set of accessories and reagents needed to start using the instrument right away. The 3500 Dx Genetic Analyzer CS2 installation includes a full install qualification and operational qualification, as well as instrument training to introduce you to your new genetic analyzer.

The 3500 Dx is backed by a comprehensive Service & Support program with options to purchase additional services depending upon your laboratory maintenance and audit requirements.

Intended Use
The Applied Biosystems® 3500 Dx and 3500xL Dx Genetic Analyzers CS2 with 3500 Dx Series Software 2011 (v1) are in vitro diagnostic devices intended for the sequencing (detection and identification) of fluorescently labeled DNA by capillary electrophoresis.

The Applied Biosystems® 3500 Dx/3500xL Dx Genetic Analyzers CS2 with 3500 Dx Series Software 2011 (v1) are indicated for use with FDA-cleared or approved sequencing assays specifying their use and only by technologists trained in laboratory techniques, procedures, and use of the analyzer.

Note: The 3500 Dx Genetic Analyzer CS2 data collection software uses Windows 7 SP0 operating system. This makes the currently available RUO secondary analysis software incompatible for use on the same system. A separate computer is required to do secondary analysis if operating in RUO mode.

Applied Biosystems™ RapidHIT™ ID System Upgrade (Applied Biosystems™)

The Applied Biosystems RapidHIT ID System Upgrade gives IntegenX RapidHIT ID System owners the ability to upgrade their system to the latest Applied Biosystems-branded version. The upgrade provides improved system reliability and performance, and enables the system to be sample/data accessioning workflow-capable.

Before upgrading, please consume your remaining IntegenX RapidHIT ID consumables as several legacy consumables, such as the primary cartridges, are not compatible with the Applied Biosystems-branded RapidHIT ID System.

For more details or questions, please contact your local sales representative or local distributor.

Genetic Analyzer Upgrade Kit (3500 to 3500xL) (Applied Biosystems™)

This kit allows you to upgrade your 8 capillary 3500 Genetic Analyzer to a 24 capillary 3500xL expanding the capabilities of your instrument. You’ll be able to take advantage of a dramatic increase in throughput and in overall laboratory productivity. The upgrade is simple and completed within a day. It does not involve any changes to the computer or software so you will not need to re-verify these components of your system.

• 8 capillary system can easily be upgraded to a 24-capillary system
• New single-line 505 nm, solid-state long-life laser—utilizes a standard power supply; requires no heat-removal ducting
• Powerful, integrated data collection and primary analysis software provides real-time assessment of data quality
• Radio Frequency Identification (RFID) technology tracks key consumables data and records administrative information
• Advanced multiplexing capabilities for DNA fragment analysis with up to six unique dyes
• Unrivaled application flexibility—one array and one polymer are used for most applications
• Simple setup, operation and maintenance—the easiest-to-run, easiest-to-own DNA sequencer to date

For Research Use Only. Not for use in diagnostics procedures.

3500xL Genetic Analyzer for Human Identification (Applied Biosystems™)

The 24-capillary 3500xL Genetic Analyzer sets the standard in capillary electrophoresis. The 3500-series instruments are the first genetic analyzers designed with a specific feature set and workflow for the Human Identification application. The complete product combines the instrument with Applied Biosystems™ reagents, consumables and software, as well as industry leading support, to provide an integrated HID system solution that significantly improves ease-of-use and application efficiencies.

• Increased Consistency – Reduced signal variation with factory standardization and optional in-lane normalization
• Real-Time Data Quality Assessment – On instrument data evaluation features provide rapid identification and re-injection of samples requiring additional processing
• Improved Thermal Control – Smaller oven design and improved door seal for more consistent data migration
• HID Specific Workflow – Pre-configured for Applied Biosystems® amplification kits to simplify run setup and software navigation
• Effortless Consumable Installation – Convenient one-time use consumable packaging
• Consumable Tracking with RFID Technology – On-instrument, real-time monitoring of consumable consumption and expiration
• Enhanced Throughput – Faster data generation with 8 or 24 capillary arrays and shorter run times
• Improved Polymer Pump Design – Reduced waste and fewer bubbles for better data quality
• Simplified Instrument Installation & Operation – New solid-state laser eliminates need for high voltage wiring and external venting
• Streamlined Instrument Maintenance – HID specific performance check and maintenance scheduling tools
• Data Chain of Custody – Controlled access and tracking through Security, Audit and eSig features

For more information, please contact your Sales Representative.

3500 Genetic Analyzer for Resequencing (Applied Biosystems™)

This 8-capillary Genetic Analyzer is specifically configured with software for resequencing applications.

We set a new standard in capillary electrophoresis with the 8-capillary 3500 Genetic Analyzer. These instruments are specifically designed to support the demanding performance needs of validated and process controlled environments, while retaining the unsurpassed application versatility that life science researchers expect from us.

• An 8 capillary system that can easily be upgraded to a 24-capillary system when you’re ready.
• New single-line 505 nm, solid-state long-life laser – utilizes a standard power supply; requires no heat-removal ducting.
• Powerful, integrated data collection and primary analysis software provides real-time assessment of data quality.
• Radio Frequency Identification (RFID) technology tracks key consumables data and records administrative information.
• Advanced multiplexing capabilities for DNA fragment analysis with up to six unique dyes.
• Unrivaled application flexibility – one array and one polymer are used for most applications.
• Simple setup, operation and maintenance – the easiest-to-run, easiest-to-own DNA sequencer to date.

Accurate Reliable Data Quality
The 3500 series systems significantly improves signal uniformity from instrument-to-instrument, run-to-run, and capillary-to-capillary. With a combination of intelligent hardware, powerful new algorithm and reagent combinations, these methods provide major reduction in the range of signal peak heights obtained across multiple 3500 series instruments (see figure 1).

Improved Sizing Precision
New thermal sub-system design gives enhanced performance in demanding fragment applications enabling improved sizing precision versus previous generations of capillary electrophoresis platforms (see figure 2).

Ready to Use Consumables With RFID Tags
The 3500 series introduces ready-to-use consumables with pre-packaged polymer pouches, cathode and anode buffer containers and easy-to-install capillary arrays. Each of these consumables is integrated with RFID tags that enable viewing, tracking and reporting of critical information about reagents and consumables including usage, lot number, part number, expiry date and on-instrument lifetime within the 3500 Series Data Collection Software (see figures 3 and 4).

Easy to Use New Data Collection Software
3500 Series Data Collection software breaks new ground in user-friendly navigation with an intuitive dashboard design, highly visible buttons for common operations, easy-to-read graphical displays to monitor the state of consumables and handy maintenance scheduling calendar functionality. New functionality includes simplified plate set-up, built-in primary analysis with quality control, so you can make decisions about the quality of data as it is produced on the instrument without the need to transfer output files into secondary analysis software packages (see figures 4 & 5).

For Research Use Only. Not for use in diagnostics procedures.

HID Ion GeneStudio™ S5 System (Ion Torrent™)

The HID Ion GeneStudio S5 System is a semiconductor-based next-generation sequencing (NGS) system that enables simple targeted sequencing workflows. The system is optimized to provide affordability for labs focused on smaller panels and with lower sequencing throughput requirements. With cartridge-based reagents, the system is simple to use and offers scalability and flexibility. It uses Ion 5 Series chips to support a broad range of forensic sequencing applications, including mitochondria sequencing, STR analysis, and SNP genotyping.

Features of the HID Ion GeneStudio S5 System include:
• Select the chip (Ion 510–540 chip) that fits your application and throughput needs to achieve from 2–80 million reads per run
• Reduce setup time and complexity with cartridge-based plug-and-play reagents
• Complete run and analysis in hours and move forward with your experiments

The Ion GeneStudio S5 Series
The HID Ion GeneStudio S5 Series sequencers share the same foundational technology and fluidic architecture across all three instruments: this HID Ion GeneStudio S5 System, the HID Ion GeneStudio S5 Plus System, and the HID Ion GeneStudio S5 Prime System. The primary difference across the three instruments is on-sequencer analysis time.

Speed
The HID Ion GeneStudio S5 Series sequencers leverage the speed of semiconductor sequencing to enable the production of high-quality sequencing data in a few hours and enable you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time when paired with the HID Ion Chef System.

Simplicity
With single-day installation, a straightforward user interface, and cartridge-based reagents, the HID Ion GeneStudio S5 Series sequencers are easy to use. Combined with Precision ID library prep technology for target selection, the HID Ion Chef System for automated library and template preparation, and Converge Software for automated analysis, forensic sequencing is simpler than ever.

Small sample input
Low input DNA amounts from challenging sample types such as touch DNA or other forensic samples can be difficult to sequence on competitor next-generation sequencers. However, with Precision ID library preparation and sequencing technology and the HID Ion GeneStudio S5 Series sequencers, you can use as little as 100 pg of DNA input and achieve accurate, robust results.

Scalability
Why buy multiple systems for your lab when you can modulate your throughput by chip selection on a single next-generation sequencer? The Ion 5 Series chips that run on the HID Ion GeneStudio S5 Series systems provide several throughput options, so your lab has the flexibility to scale from small to large projects, enabling multiple forensic applications on a single system.

Simple analysis and storage solutions
Torrent Suite Software and Converge Software make NGS easy for beginners and experts alike. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Converge Software (Thermo Fisher Cloud or local options available based on your needs).

Services and support
With more than 2,000 field personnel, Thermo Fisher Scientific has the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so you can be confident that we will be there when and where you need us most.

Service and support plans—comprehensive plans to maximize instrument performance and help ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data

5500 Genetic Analyzer (Applied Biosystems™)

Built on three decades of sequencing expertise and powered by the proven accuracy of ligation-based sequencing, the new 5500 Genetic Analyzer provides a robust, affordable next-generation sequencing platform for every lab. Designed to give you the choice to optimize for turnaround time or throughput, the 5500 Genetic Analyzer is a highly accurate, cost-effective solution for analyzing one or many samples.

Key Benefits
• Sequencing right here, right now
• Cost-effective sequencing runs with individually configurable lanes
• Superior low frequency variant detection for whole exome sequencing or targeted resequencing
• Reproducibility, reliability, and quality for your RNA applications
• Confidence and uniformity in multiplexing with up to 96 barcodes
• Optimal analysis solutions for streamlined productivity and freedom to operate

Explore the Depths of Translational Research
With Exact Call Chemistry, the industry-leading accuracy of the 5500 Genetic Analyzer helps you get definitive answers about biological variation for applications like whole exome, RNA-seq, and structural variation.

Customize the System for Your Projects
The 5500 Genetic Analyzer allows you to tailor your sequencing runs precisely for your research. The six independent FlowChip lanes and Pay-Per-Lane Sequencing (PPL-Seq™) allow you to configure the instrument to different project scales and application types. Additionally, the system’s intelligent barcode kits can accommodate from one to hundreds of samples in a single run.

Don’t Wait
With the 5500 Genetic Analyzer, the unique capability to run each FlowChip lane independently allows you to turn around results in the shortest time possible. Now you can explore the genome, transcriptome, and epigenome with a hypothesis-neutral platform that combines powerful sequence data generation with premium accuracy. Whether you're running whole exome, RNA-seq, or a structural variation experiment, the 5500 Genetic Analyzer is designed to deliver high-quality results in a time-sensitive and cost-effective manner.

Perform Sequencing with Ease
Designed in collaboration with core facilities and principal investigators, the integrated 5500 Genetic Analyzer provides an intuitive and user-friendly workflow from sample preparation to data analysis.

Workflow Benefits Include:
• Embedded sequencing controls to enable real-time monitoring of data quality throughout the entire workflow
• System alerts to help maximize data quality and system performance, and to track reagent usage during the course of the sequencing run
• Easy-to-use software, 60% smaller data footprints, workstation computing, and standard base sequence file formats to facilitate setup, daily operations, and seamless integration with data analysis tools

Join the Era of Genomic Medicine
The throughput, broad range of applications, system flexibility, and intuitive design of the 5500 Genetic Analyzer address the needs of core and services laboratories, and basic and clinical research labs, to take sequencing into every scientific discipline.

A Community of Support
With more than 2,000 field personnel, we have the most extensive network of dedicated Field Application Specialists and Service Engineers in the industry. You can feel confident that we will be there when and where you need us most.

The 5500 Genetic Analyzer is For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Ion GeneStudio™ S5 System with SmartStart (Ion Torrent™)

The Ion GeneStudio S5 System is a semiconductor-based next-generation sequencing (NGS) system that enables simple targeted sequencing workflows. It is optimized to provide affordability for labs focused on smaller panels and lower sequencing throughput requirements. Combining an extended warranty with your system purchase helps extend the life of your investment.

This package includes the Ion GeneStudio S5 System and SmartStart orientation. Key features include:
• Select the chip (Ion 510–540 chip) that fits your application and throughput needs to achieve from 2–80 million reads per run
• Reduce setup time and complexity with cartridge-based plug-and-play reagents
• Complete run and analysis in hours and move forward with your experiments
• Increase efficiency and become operational faster with SmartStart orientation

For detailed instrument information and specifications, see the Ion GeneStudio S5 System.

Get up and running quickly with SmartStart
SmartStart orientation is carried out by a Field Application Scientist (FAS) to get you up and running quickly in your lab and reduce downtime. SmartStart is the first step of your education journey and is designed to help you work smarter and with greater efficiency. It includes:
• 1-day technology overview and instrument workflow
• 1-day hands-on application workflow training
• 10 hours bioinformatics consultancy

Content will vary depending on your level of knowledge and experience.

SeqStudio™ Genetic Analyzer System with SmartStart (Applied Biosystems™)

The Applied Biosystems SeqStudio Genetic Analyzer is a 4-capillary, fluorescence-based capillary electrophoresis system designed to provide users with an integrated experience that is easy, efficient, and versatile for research in genetic analysis. The all-in-one reagent cartridge allows easy operation for multiple users with the flexibility to perform both sequencing and fragment analysis in a single run. The simplified SeqStudio Plate Manger software is well-suited for first-time and experienced users. Be more connected to your data than ever with intuitive browser-based software and cloud-based connectivity options for remote monitoring, and data transfer and analysis.

The SeqStudio system gives you the same data quality, reliability, and support you have come to expect from the Applied Biosystems brand with a modernized experience. Same workflow, same trusted data. Now with one-click convenience.

Key features
• Simplified instrument software with interactive touch screen for greater ease of use
• Minimized hands-on setup time with integrated reagents cartridge (SeqStudio Cartridge)
• Application flexibility to run Sanger sequencing and fragment analysis on the same run
• Connectivity: Wi-Fi or wired Ethernet connection
• Web-enabled remote monitoring capability
• Consumables usage tracking through radio frequency identification (RFID)

This package includes:
• 4-capillary SeqStudio Genetic Analyzer
• SeqStudio Analysis Software (GeneMapper, Sequencing Analysis, Minor Variant Finder, Variant Reporter, and SeqScape)
• SeqStudio Plate Manager Software
• 1Day SmartStart Orientation
Note: SeqStudio Cartridge and other system consumables and reagents sold separately

Just click. That's it.
Load up your samples, click in the cartridge, and go—no need for technical experts for setup or maintenance, no calibration before each run, and no installation of capillaries, polymer, and anode buffer. The cartridge is stable for 4 months on the instrument.

Access your data anytime, anywhere*
This system features Thermo Fisher Cloud connectivity so you can set up your run, check its progress, and access your data from wherever you have Internet access, all without the need to stay in the lab.* Get the same data quality, service, and support you’ve come to expect from Applied Biosystems technology with a modernized experience at a price any lab can afford.
* Internet connection and Thermo Fisher Cloud account required.

Service, support, and training
We offer a range of service options, plans, and warranties to improve productivity, increase instrument uptime, and lower the total cost of ownership. SmartStart orientation helps get you started with your new instrument more quickly.

Software
SeqStudio Genetic Analyzer Instrument Software, v 1.1Software update fileRelease notesEULA
SeqStudio Genetic Analyzer Plate Manager Software, v1.1Windows installerMac installer
Sequence Analysis Software patch for SeqStudio supportInstallerRelease notes 
SeqScape Software patch for SeqStudio supportInstallerRelease notes 
Variant Reporter Software patch for SeqStudio supportInstallerRelease notes 
GeneMapper Client Software patch for SeqStudio supportInstallerRelease notes 
GeneMapper Full Software patch for SeqStudio supportInstallerRelease notes 
Minor Variant Finder Software patch for SeqStudio supportInstaller 


3130 Genetic Analyzer to 3130xl Genetic Analyzer Upgrade Kit (Applied Biosystems™)

This is a system upgrade, from the 3130 Genetic Analyzer to the 3130xl Genetic Analyzer.

The 3130xl Genetic Analyzer is the latest generation of 16-capillary electrophoresis instruments for the medium throughput laboratories. The system offers industry-leading performance, plus sophisticated automation capabilities allowing researchers to save time, reduce costs and increase productivity.

Important Note: 3100 System Sequencers will be retired at the end of 2011. Take advantage of our limited time promotion to either TRADE-IN your 3100 for a brand new 3500 or UPGRADE to a 3130. Please contact your local Sales Representative to learn more.

For Research Use Only. Not for use in diagnostics procedures.

HID Ion Chef™ Instrument (Ion Torrent™)

The HID Ion Chef System is the next generation of workflow simplification products for the HID Ion GeneStudio S5 Series sequencers. The HID Ion Chef System provides automated library preparation, template preparation, and chip loading for users at any experience level. In less than 15 minutes of up-front hands-on time and with the use of pre-packaged library preparation reagent kits, the HID Ion Chef System provides a convenient walk-away workflow resulting in equalized, pooled libraries ready for templating. The automated workflow supports Precision ID panels for both one- and two-pool designs. After library preparation, less than 15 minutes of hands-on time is required to set up the HID Ion Chef System to perform fully automated template preparation, producing one or two chips ready for sequencing. Automating your sample preparation workflows on the HID Ion Chef System results in significantly higher productivity.

The HID Ion Chef System:
• Simplifies the workflow
• Minimizes sources of user-introduced variability
• Helps save time and labor
• Supports sequencing preparation for the HID Ion GeneStudio S5 Systems

The HID Ion Chef System features include:
• Automated Precision ID library preparation, template preparation, and chip loading
• Cartridge-based reagent system
• Sample- and reagent-tracking capability
• Intuitive user interface
• On-board diagnostics

Simplify the forensic NGS workflow
The HID Ion Chef System simplifies the forensic next-generation sequencing (NGS) workflow by integrating several manual and instrument steps into a single process. The HID Ion Chef System workflow now incorporates all steps of library preparation (targeted PCR amplification with respective primer panel, partial digestion of primer sequences, adapter/barcode ligation, purification, library equalization and pooling), as well as all steps of template preparation and chip loading. The simple, automated workflow provides easy access for users of any experience level.

Minimize variability and load chips reproducibly
The HID Ion Chef System provides reproducible chip loading by automating multiple manual chip-loading steps. The sophisticated visual system inside the HID Ion Chef System is designed to help reduce user-introduced error and variability by providing barcode reading and positive identification of samples, chips, and reagents. The visual system performs the setup check before the run, as well as the reagents and consumables load and unload check, calibration, and diagnostics.

Save time and labor
The HID Ion Chef System enables significant time and labor savings by offering quick and easy setup for both library preparation and templating that typically requires less than 15 minutes of hands-on time for each step.

Support for all Ion Torrent sequencing workflows
The flexible HID Ion Chef System is designed to provide automated and consistent Precision ID library preparation and template preparation for sequencing on the HID Ion GeneStudio S5 systems using any of the corresponding chips or template preparation and sequencing chemistries.

Services and support
With more than 2,000 field personnel, Thermo Fisher Scientific has the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so you can be confident that we will be there when and where you need us most.

Service and support plans—comprehensive plans to maximize instrument performance and help ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data

Ion GeneStudio™ S5 Prime System Extended Warranty Package (Ion Torrent™)

The Ion GeneStudio S5 Prime System is a semiconductor-based next-generation sequencing (NGS) system that enables simple targeted sequencing workflows. For core and service labs requiring maximum throughput and rapid turnaround time from a benchtop NGS system, the Ion GeneStudio S5 Prime System enables unparalleled breadth and depth, from large panels or exomes to clinical oncology research focused on low allele frequency applications. Combining an extended warranty with your system purchase helps extend the life of your investment.

This package includes the Ion GeneStudio S5 Prime System, SmartStart orientation, and an extended warranty. Key features include:
• Select the chip (Ion 510–550 chip) that fits your application and throughput needs to achieve from 2–130 million reads per run
• Reduce setup time and complexity with cartridge-based plug-and-play reagents
• Complete run and analysis in hours and move forward with your experiments
• Increase efficiency and become operational faster with SmartStart orientation
• Receive fast repair from certified service engineers
• Minimize instrument downtime by troubleshooting with experienced Technical Support teams

For detailed instrument information and specifications, see the Ion GeneStudio S5 Prime System.

Get up and running quickly with SmartStart
SmartStart orientation is carried out by a Field Application Scientist (FAS) to get you up and running quickly in your lab and reduce downtime. SmartStart is the first step of your education journey and is designed to help you work smarter and with greater efficiency. It includes:
• 1-day technology overview and instrument workflow
• 1-day hands-on application workflow training
• 10 hours bioinformatics consultancy

Content will vary depending on your level of knowledge and experience.

Extended warranty plan
Add coverage to your existing manufacturer’s limited warranty with an extended warranty. Each extended warranty includes a planned maintenance visit. Should your instrument require a repair, the extended warranty coverage includes parts, labor, and travel at no additional cost. In addition, you’ll receive:
• On-site guaranteed 2-day response time*
• Scheduled on-site planned maintenance (PM)
• Priority access to Remote Service Engineers

Certain exclusions apply. Contact your Services and Support Representative for details at service.sales@thermofisher.com.

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Ion S5™ System (Ion Torrent™)

The Ion S5™ next-generation sequencing system enables a simple targeted sequencing workflow for your lab at an affordable price, without compromising on performance or reliability. The Ion S5 System leverages the speed of semiconductor sequencing with impressive on-board computing power, to enable the production of high quality sequencing data in as little as 2.5 hours and enable you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time on the Ion Chef™ System and the Ion S5 System. The Ion S5 System is simple to use with cartridge-based reagents and offers superior scalability and flexibility to support a broad range of high throughput sequencing applications, from microbial genomes and gene panels to exomes and transcriptomes, using our 5 Series chips.

Speed
Some research decisions can’t wait. A few hours could make all the difference in your quest for the right answer.With other light-based sequencers you could wait almost 60 hours for results. With the Ion S5 System you get results in as little as 24 hours (with a 2.5-4 hour sequencer run time and overnight Ion Chef System run).

Simplicity
With single-day installation, a straightforward user interface, and cartridge-loaded reagents, the Ion S5 System is easy to use. Beyond this, the system is part of a workflow that allows you to go from DNA to data with only 45 minutes of total hands-on time on the Ion Chef System and the Ion S5 System, significantly less than other targeted sequencing solutions that require as much as 2.5 hours of hands-on time. Combined with Ion AmpliSeq™ technology for target selection, the Ion Chef™ System for automated library and template preparation, and Ion Reporter™ Software for automated variant annotation, targeted sequencing becomes simpler than ever.

Small sample input
Low input DNA for challenging samples types, such as formalin-fixed paraffin-embedded (FFPE) tissue, retrospective samples from fine needle aspirates, and cell-free DNA extracted from blood (cfDNA) can be difficult to sequence on competititor next-generation sequencers. However, with Ion AmpliSeq technology and the Ion S5 Sequencer, you can use as little as 10 ng input DNA or RNA.

Scalability
Why buy multiple systems for your lab when you can run all of your targeted sequencing or microbial applications on a single next-generation sequencer? The Ion S5 System has a modular build, so your lab has the flexibility to do multiple targeted sequencing applications on a single system.

Simple analysis and storage solutions
Whether you are new to next-generation sequencing or an expert user, Torrent Suite™ Software and Ion Reporter™ Software make it easy for you to get started with next-generation sequencing. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Ion Reporter Software (Cloud or local options available based on your needs).

Services and support
With more than 2,000 field personnel, Thermo Fisher Scientific has the most extensive network of dedicated Field Application Specialists and Service Engineers to work with you, so you can be confident that we will be there when and where you need us most.

Service and support plans—comprehensive plans to maximize instrument performance and ensure availability of critical systems
Qualification services—document and ensure instrument is installed, operating, and performing to manufacturer’s specifications
Training—courses for experimental design, data analysis, troubleshooting, applications, and instrument operation
Bioinformatics—tailored support for NGS informatics execution, software use, data analysis, and downstream applications
DataSafe Solution—storage and back-up strategy, design, hardware, and support for all lab data