Shop All Single-Use BioProcess Containers

Impeller sleeve for open-top mixing, for 2000L HyPerforma™ Single-Use Mixer BioProcess Container (BPC) (Thermo Scientific™)

Support mixing applications in bioproduction using Thermo Scientific™ Bioprocess Containers (BPC) for Thermo Scientific™ HyPerforma™ Single-Use Mixer, with impeller-based mixing in open or closed designs.

Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability

Productainer™ BioProcess Container (BPC), 50 L with 4 Top and 1 Bottom Ports, 3D Single-Use (Thermo Scientific™)

The Thermo Scientific™ Productainer™ BioProcess Container (BPC), 50 L 3D system is composed of CX5-14 single web, multi-layer plastic film and includes 4 top ports and 1 bottom port. The 3D square tube design with bottom port dispense is for use with conical, bottom-drain drums.

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All 3D BPCs are constructed in an ISO 7 cleanroom under cGMP conditions.
• All 3D BPCs are designed to fit the full range of support containers, both square and cylindrical – from 50 to 2000 L.

Applications of the Thermo Scientific 3D BPC include:
• Hydration and sterilization of process buffers, liquids, and culture media.
• Chromatography feed and fraction collection.
• Storage and transport of bulk drug product and bulk drug precursors.
• Harvest from and feed into bioreactors and fermentors.
• Dispensing, packaging, and storage of cell culture media, buffers and process liquids.

Customize standard BPC systems for optimized single-use technology. Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.

HyPerforma™ Rocker BioProcess Container (BPC) (Thermo Scientific™)

The Thermo Scientific Rocker Bioprocess Container (BPC) is manufactured for use with the Thermo Scientific Rocker Bioreactor and is available in three volumes: 10, 20, and 50 L. Rocker BPCs are manufactured using a multi-layer, polyolefin-based, slip agent-free film. This film provides superior extractables and leachables profiles, water vapor and oxygen barriers, and complete fluid integrity. Each lot is routinely tested for bacterial endotoxins.

Rocker BPC features include:
• Shipped gamma-irradiated (25 to 40 kGy) and ready for use
• Routinely monitored for particulates per USP <788>
• Lot release requires endotoxin levels to test below 0.25 EU/mL
• All wetted materials are USP class VI-compliant and animal derived component-free (ADCF)

Applications
• Suspension and adherent cell culture processes

Labtainer™ BioProcess Container (BPC), 2L with 3 Ports, MPC Insert and Injection Port, 2D BPC (Thermo Scientific™)

The 2 L Thermo Scientific™ Labtainer™ BPC, 2D system is composed of CX5-14 single web, multi-layer plastic film and includes 3 top ports (2 with MPC inserts, 1 injection port).

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All Labtainers are constructed in an ISO 7 cleanroom under cGMP conditions.

Applications of the Thermo Scientific Labtainer BPC include:
• Harvest from, feed into, and collect samples from bioreactors and fermentors.
• Buffer, culture media, and process liquid preparation and storage.
• Chromatography feed and fraction collection.
• Harvest, storage and transport of bulk drug product and bulk drug precursors.

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.

Labtainer™ BioProcess Container (BPC), 2L with 2 Ports, Luer Lock, 2D BPC (Thermo Scientific™)

The 2 L Thermo Scientific™ Labtainer™ BPC, 2D system is composed of CX5-14 single-web, multi-layer film, and includes 2 edge ports (male and female luer lock connections).

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All Labtainers are constructed in an ISO 7 cleanroom under cGMP conditions.

Applications of the Thermo Scientific Labtainer BPC include:
• Harvest from, feed into, and collect samples from bioreactors and fermentors.
• Buffer, culture media, and process liquid preparation and storage.
• Chromatography feed and fraction collection.
• Harvest, storage and transport of bulk drug product and bulk drug precursors.

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.

Impeller sleeve for open-top mixing, for 500/1000L HyPerforma™ Single-Use Mixer BioProcess Container (BPC) (Thermo Scientific™)

The Impeller sleeve for open-top mixing (500/1000L) supports mixing applications in bioproduction using Thermo Scientific™ Bioprocess Containers (BPCs) for Thermo Scientific™ HyPerforma™ Single-Use Mixer, with impeller-based mixing in open or closed designs.

Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability

imPULSE™ Single-Use Mixer Vent Line Transfer Assembly (Thermo Scientific™)

The Thermo Scientific™ Vent Transfer Assembly, 1.27 cm (.5 in.), consists of silicone tubing with MPX inserts with caps and a sanitary barb with a gasket, end cap, and push/pull clip. This transfer assembly is compatible with the Thermo Scientific™ imPULSE™ Single-Use BioProcess Containers (BPC), ranging from 30 L to 750 L.

Features
• Minimizes bioburden due to construction under sterile cGMP conditions

Tubing specifications:
• Tubing: Silicone, 15.2 x 15.2 x 152.4 cm (6 x 6 x 60 in.), ID x OD: 1.27 x 1.91 cm (0.5 x 0.75 in.)
• T1: MPX body + cap
• T2: MPX insert + cap
• T3: 3.8 cm (1.5 in.) sanitary x 1.27 cm (0.5 in.) barb with gasket, end cap, push/pull clip

Thermo Scientific™ Single-Use Fermentor BioProcess Container, Aegis5-14 film, pH/DO sensor, foam sensor, Meissner inlet, two 10-inch exhaust filters, 300 L (Thermo Scientific™)

This 300 L Thermo Scientific Single-Use Fermentor (SUF) BioProcess Container (BPC) is composed of Aegis5-14 film, a five-layer, animal-origin free film, and includes a Mettler Toledo single-use pH and DO sensor, foam sensor, Meissner inlet, two 10-inch exhaust filters, and condenser.

All SUF BPCs are constructed in an ISO 7 (Class 10,000) cleanroom, which complies with cGMP standards.

Features:
• Manufactured with industry-leading Aegis5-14 film
• C-flex tubing that can be used with tubing welder and various connection options
• Configurable to meet your process needs, including options for single-use sensing (DO, pH, and pressure)

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library, with over 2,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors
Filters—used for bioburden reduction; sterilization grade filters and gas filters
Tubing—thermoplastic elastomers, platinum-cured silicone
Sample ports—septum-style and needle-free ports
Clamps—sliders, pinch, and crimp bands

Labtainer™ BioProcess Container (BPC), 100mL with 2 Ports, Luer Lock and MPC Insert, 2D BPC (Thermo Scientific™)

The 100 mL Thermo Scientific™ Labtainer™ BPC, 2D system is composed of CX5-14 single-web, multi-layer film, and includes 2 edge ports with luer lock body and MPC insert.

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All Labtainers are constructed in an ISO 7 cleanroom under cGMP conditions.

Applications of the Thermo Scientific Labtainer BPC include:
• Harvest from, feed into, and collect samples from bioreactors and fermentors.
• Buffer, culture media, and process liquid preparation and storage.
• Chromatography feed and fraction collection.
• Harvest, storage and transport of bulk drug product and bulk drug precursors.

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.

Labtainer™ BioProcess Container (BPC), 20L with 3 Ports, MPC Insert, 2D BPC (Thermo Scientific™)

The 20 L Thermo Scientific™ Labtainer™ BPC, 2D system is composed of CX5-14 single web, multi-layer plastic film and includes 3 top ports (2 with MPC inserts, 1 plugged port).

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All Labtainers are constructed in an ISO 7 cleanroom under cGMP conditions.

Applications of the Thermo Scientific Labtainer BPC include:
• Harvest from, feed into, and collect samples from bioreactors and fermentors.
• Buffer, culture media, and process liquid preparation and storage.
• Chromatography feed and fraction collection.
• Harvest, storage and transport of bulk drug product and bulk drug precursors.

Customize standard BPC systems for optimized single-use technology
Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.

Standard Fluid Transfer Assembly Adaptor Set, 1/4 in. (1/16 in. wall) to 1/2 in. (Thermo Scientific™)

Thermo Scientific™ Standard Fluid Transfer Assembly products increase single-use product flexibility. They connect to our standard Labtainer BPCs, Productainer BPCs, single-use bioreactors, mixers, and fermentors right on the shop floor. And they deliver simplified connectivity and enable greater process efficiency for most upstream and downstream process operations.

• One set of stocked products reduces the number of customized stock keeping units (SKUs), simplifies the ordering process, and reduces product storage requirements
• Multiple manufacturing sites ensure security in product supply
• Produced under cGMP conditions in ISO 7 clean areas to ensure a high level of quality
• Characterized using ISO, USP, EP, and ASTM test methods to validate performance

Standard Fluid Transfer Assembly products interconnect with Thermo Scientific standard BPC products to deliver a comprehensive and complete set of single-use products to meet the needs of your facility or process. Designed to aid many common shop floor processes such as sampling, transfer, and filling, a fit-for-purpose solution in the required tubing size and length can be easily selected from these designs.

All Standard Fluid Transfer Assembly products are constructed of capped-end connectors and thermoplastic elastomer (TPE) tubing for use with welders. The Adaptor Set is designed to link tubing of differing sizes and is available in a series of size combinations.

These Standard Fluid Transfer Assembly products provide a common set of products that addresses an expansive set of needs while decreasing the number of customized stock keeping units (SKUs), simplifying the ordering process and reducing storage requirements. They are manufactured at multiple sites globally to minimize concerns of production shutdown from supply shortages. These products are built to contribute to the performance and quality of your process at the highest level.

PowderTainer™ II 1 to 25kg Single-Use BPC for powder applications, 5kg (Thermo Scientific™)

The 5 kg Thermo Scientific™ Powdertainer™ II BioProcess Container (BPC) is a 2D powder handling system composed of CX3-9 film that includes 2 ports (1 wash down line, 1 powder port). The Powdertainer BPC is specifically designed for powder containment and discharge applications, and maintains a closed system for maximum recovery of powder while minimizing the risk of cross contamination.

Features:
• Three-inch tri-clamp port designed for secure connection to, and easy integration, with existing formulation vessels.
• Powdertainer BPC features suspensor handle for support during discharge, as well as neck clamp to retain powder prior to discharge.
• Use this system to eliminate post-use cleaning steps required with re-useable containers.

Applications of the Thermo Scientific Powdertainer BPC include:
• Storage and delivery of powder culture media and buffers.
• Storage and dispensing of pre-weighed chemicals and other process powders.

DHX™ Heat Exchanger BioProcess Container (BPC), ASI™ 26/77 film, ReadyMate connections, drain ports, four 6-L BPCs (Thermo Scientific™)

The Thermo Scientific™ DHX™ Heat Exchanger Single-Use BioProcess Container (BPC) is a 2D system consisting of four 6 L BPCs, with drain. It is composed of Thermo Scientific™ ASI™ 26/77 Polyethylene Film, with interconnecting C-Flex tubing and ReadyMate DAC end connections. The DHX Heat Exchanger and DHX BPC each features a serpentine pattern, creating a sterile fluid path for the process fluid. The BPC fits tightly between the stainless steel DHX Heat Exchanger plate system, and after loading, no further operator interaction is required. The customer has the option of utilizing up to 4 BPCs in the DHX unit.

Features
• Eliminates post-use cleaning steps required with reusable containers, helping to reduce cross-contamination risks
• Provides sterile processing environment without the cost and time of clean-in-place or steam-in-place sterilization (CIP/SIP)
• Minimizes bioburden by using the DHX Heat Exchanger unit and DHX BPCs to address weak points in a CIP system or sanitation process (typically required for stainless steel equipment)
• Reduces maintenance and life cycle cost due to its unique design
• Increases volume capacity via parallel connection between DHX units

Applications
• cGMP commercial and clinical biotherapeutics, vaccines, and other biologic processes
• Upstream applications, including media hold, harvest cooling, and harvest hold
• Downstream applications, including harvest hold, buffers, protein purification, and bulk drug substance

BioProcess Containers (BPC), 200, for HyPerforma™ Single-Use Mixer and docking tank, liquid-to-liquid w/probe ports (Thermo Scientific™)

The 200L Thermo Scientific™ Bioprocess Container (BPC) with probe ports is for use with the Thermo Scientific™ HyPerforma™ Single-Use Mixer and docking tank for liquid-to-liquid mixing.

Single Use Mixer (S.U.M.) BPC options include:
• Open top liner for media/buffer hydration
• Closed BPC with powder port for contained media/buffer hydration
• Closed BPC with powder port and monitoring probe capability
• Closed BPC for liquid-liquid mixing of critical sterile solutions such as pooling of fractions or processing of intermediate solutions
• Closed BPC for liquid-liquid mixing with monitoring probe capability

Productainer™ BioProcess Container (BPC), 200 L with 2 Top Ports, 3D Single-Use (Thermo Scientific™)

The Thermo Scientific™ Productainer™ BioProcess Container (BPC) 200 L 3D system is composed of CX5-14 single web, multi-layer plastic film and includes 2 top ports. The 3D square tube design with top dispense is for use with flat-bottom Thermo Scientific™ drums.

Features:
• Use this system to eliminate post-use cleaning steps required with re-useable containers, and to reduce cross-contamination risks.
• All 3D BPCs are constructed in an ISO 7 cleanroom under cGMP conditions.
• All 3D BPCs are designed to fit the full range of support containers, both square and cylindrical – from 50 to 2000 L.

Applications of the Thermo Scientific 3D BPC include:
• Hydration and sterilization of process buffers, liquids, and culture media.
• Chromatography feed and fraction collection.
• Storage and transport of bulk drug product and bulk drug precursors.
• Harvest from and feed into bioreactors and fermentors.
• Dispensing, packaging, and storage of cell culture media, buffers and process liquids.

Customize standard BPC systems for optimized single-use technology. Choose from the industry’s largest component library – with over 20,000 unique components that include:
Fittings—straight, reducing, elbow, T-style, X-style, and cross-style.
Connectors—quick connectors/disconnectors, aseptic connectors and disconnectors, steam-to and steam-through connectors.
Filters—used for bioburden reduction; sterilization grade filters and vent filters.
Tubing—thermoplastic elastomers, platinum-cured silicone.
Sample ports—septum-style and needle-free ports.
Clamps—sliders, pinch, and crimp bands.