Shop All Lipid Conjugates

BODIPY™ FL C16 (4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Hexadecanoic Acid) (Invitrogen™)

The green fluorescent fatty acid, BODIPY® FL C16 can be used as a synthetic precursor to a wide variety of fluorescent phospholipids. Unlike fluorophores like pyrene, DPH and NBD, BODIPY® dyes are relatively environment insensitive and is fluorescent in both aqueous and lipid environments.

1-Pyrenedecanoic Acid (Invitrogen™)

1-pyrenedecanoic acid is a fluorescent fatty acid analog with the environment sensitive pyrene attached to the terminal (omega) carbon atom that is furthest from the carboxylate moiety.

Texas Red™ 1,2-Dihexadecanoyl-sn-Glycero-3-Phosphoethanolamine, Triethylammonium Salt (Texas Red™ DHPE) (Invitrogen™)

The phospholipid, Texas Red® 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine, triethylammonium salt (Texas Red® DHPE) is labeled on the head group with the bright, red-fluorescent Texas Red® dye (excitation/emission maxima ~595/615 nm).

BODIPY™ 500/510 C4, C9 (5-Butyl-4,4-Difluoro-4-Bora-3a,4a-Diaza-s-Indacene-3-Nonanoic Acid) (Invitrogen™)

The green-fluorescent fatty acid BODIPY® 500/510 C4, C9 has the fluorophore linked within the fatty acid chain. BODIPY® fatty acids are readily metabolized by living cells to phospholipids, di- and triacylglycerols, cholesteryl esters and other natural lipids.

BODIPY™ FL C12 (4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoic Acid) (Invitrogen™)

The green fluorescent fatty acid, BODIPY® FL C12 can be used as a synthetic precursor to a wide variety of fluorescent phospholipids. Unlike fluorophores like pyrene, DPH and NBD, BODIPY® dyes are relatively environment insensitive and is fluorescent in both aqueous and lipid environments.

β-BODIPY™ FL C12-HPC (2-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoyl)-1-Hexadecanoyl-sn-Glycero-3-Phosphocholine) (Invitrogen™)

The intensely fluorescent BODIPY® (4,4-difluoro-3a,4a-diaza-s-indacene) fluorophore is intrinsically lipophilic, unlikemost other long-wavelength dyes. Consequently, probes incorporating this fluorophore are more likely to mimic the properties of natural lipids. BODIPY® fatty acid analogs like BODIPY® 500/510 dodecanoic acid (D-3823) and BODIPY FL dodecanoic acid (D-3822) undergo native-like transport and metabolism in cells. They are therefore effective tracers of lipid trafficking, as well as being useful general-purpose membrane probes.

BODIPY™ 505/515 (4,4-Difluoro-1,3,5,7-Tetramethyl-4-Bora-3a,4a-Diaza-s-Indacene) (Invitrogen™)

With its nonpolar structure and long-wavelength absorption and fluorescence, BODIPY® 505/515 can be used as a stain for netural lipds and as a tracer for oil and other nonpolar lipids.

BODIPY™ FL C5-Ceramide complexed to BSA (Invitrogen™)

BODIPY® FL C5 ceramide complexed to BSA can be used in sphingolipid transport and metabolism mechanisms. Complexing fluorescent lipids with bovine serum albuin (BSA) facilitates cell labeling by eliminating the need for organic solvents to dissolve the lipophilic probe - the BSA-complexed probe can be directly dissolved in water.

β-Py-C10-HPC (1-Hexadecanoyl-2-(1-Pyrenedecanoyl)-sn-Glycero-3-Phosphocholine) (Invitrogen™)

This phospholipid analog of phosphocholine, ß-py-C10-HPC is labeled with pyrene on the sn-2 acyl chain. Pyrene forms excimers at high concentrations, excimer emission ~470nm. Pyrene is environment sensitive, essentially nonfluorescent in water.

BODIPY™ FL C5-Ganglioside GM1 complexed to BSA (Invitrogen™)

Colocalization of fluorescent cholera toxin B conjugates and the green-fluorescent BODIPY® FL C5-ganglioside GM1 complexed to BSA observed by fluorescence microscopy provides a direct indication of the association of these molecules in lipid rafts. Complexing fluorescent lipids with bovine serum albuin (BSA) facilitates cell labeling by eliminating the need for organic solvents to dissolve the lipophilic probe - the BSA-complexed probe can be directly dissolved in water.

BODIPY™ 500/510 C1, C12 (4,4-Difluoro-5-Methyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoic Acid) (Invitrogen™)

Our C1-BODIPY 500/510 C12 is a fluorescent fatty acid analog that has been used for lipid trafficking studies and as a general membrane probe. It forms excimers and exhibits red-shifted fluorescence emission when incorporated into living cells.

β-BODIPY™ 500/510 C12-HPC (2-(4,4-Difluoro-5-Methyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoyl)-1-Hexadecanoyl-sn-Glycero-3-Phosphocholine) (Invitrogen™)

The intensely fluorescent BODIPY® (4,4-difluoro-3a,4a-diaza-s-indacene) fluorophore is intrinsically lipophilic, unlikemost other long-wavelength dyes. Consequently, probes incorporating this fluorophore are more likely to mimic the properties of natural lipids. BODIPY® fatty acid analogs like BODIPY® 500/510 dodecanoic acid (D-3823) and BODIPY FL dodecanoic acid (D-3822) undergo native-like transport and metabolism in cells. They are therefore effective tracers of lipid trafficking, as well as being useful general-purpose membrane probes.

CholEsteryl 4,4-Difluoro-5-(4-Methoxyphenyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-Undecanoate (CholEsteryl BODIPY™ 542/563 C11) (Invitrogen™)

Cholesteryl esters consist of a fatty acid esterified to the 3β-hydroxyl group of cholesterol. These very nonpolar species are the predominant lipid components of atherosclerosis plaque and low- and high-density lipoporotein (LDL and HDL) cores. The orange-red fluorescent BODIPY® 542/563 cholesteryl ester can be used as a tracer of cholesterol transport and rand as a general nonexchangeable membrane marker.

5-Dodecanoylaminofluorescein (Invitrogen™)

The lipophilic fluorescein probe, 5-dodecanoylaminofluorescein contains a C12 alkyl chain that will bind to membranes with the fluorophore at the aqueous interface and the alkyl tail protruding into the lipid interior. Lipophilic fluorescein probes are commonly utilized for fluorescence recovery after photobleaching (FRAP) measurements of lipid lateral diffusion.

BODIPY™ 493/503 (4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene) (Invitrogen™)

With its nonpolar structure and long-wavelength absorption and fluorescence, BODIPY® 493/503 can be used as a stain for neutral lipds and as a tracer for oil and other nonpolar lipids.