Shop All Organelle Stains

LysoSensor™ Blue DND-167 - Special Packaging (Invitrogen™)

LysoSensor Blue DND-167 can be used to measure the pH of acidic organelles, such as lysosomes. The LysoSensor dye becomes more fluorescent in acidic environments. The pKa of LysoSensor Blue DND-167 is ~5.1.

LysoSensor™ Green DND-189 - Special Packaging (Invitrogen™)

LysoSensor™ Green DND-189 can be used to measure the pH of acidic organelles, such as lysosomes. The LysoSensor dye becomes more fluorescent in acidic environments. The pKa of LysoSensor™ Green DND-189 is ~5.2.

LysoTracker™ Deep Red (Invitrogen™)

LysoTracker® Deep Red is a deep red-fluorescent dye for labeling and tracking acidic organelles in live cells.

Features of all LysoTracker® probes include:

• High selectivity for acidic organelles
• Effective labeling of live cells at nanomolar concentrations
• Live-cell imaging
• With excitation/emission of 647/668 nm, the same filter set can be used as used for Cy5 or MitoTracker® Deep Red

Simple, Highly Specific, One-Step Staining and Tracking of Acidic Organelles
The LysoTracker® probes consist of a fluorophore linked to a weak base that is only partially protonated at neutral pH. This allows LysoTracker® probes to freely permeate cell membranes enabling them to label live cells. LysoTracker® probes are highly selective for acidic organelles, and unlike dinitrophenyl (DNP), LysoTracker® probes do not require use of a second antibody for detection.

LysoTracker® probes are available in a variety of fluorescent colors.

LysoTracker™ Blue DND-22 - Special Packaging (Invitrogen™)

LysoTracker® Blue DND-22 is a blue fluorescent dye that stains acidic compartments in live cells with excitation/emission maxima ~373/422 nm.

ER-Tracker™ Red (BODIPY™ TR Glibenclamide), for live-cell imaging (Invitrogen™)

ER-Tracker™ Red dye is cell-permeant, live-cell stain that is highly selective for the endoplasmic reticulum (ER) that when stained using the protocol provided, the staining pattern is partially retained after fixation with formaldehyde. This stain consists of the green-fluorescent BODIPY® TR dye and glibenclamide. Glibenclamide (glyburide) binds to the sulphonylurea receptors of ATP-sensitive K+ channels which are prominent on ER; the pharmacological activity of glibenclamide could potentially affect ER function. Variable expression of sulphonylurea receptors in some specialized cell types may result in non-ER labeling.

MitoTracker™ Deep Red FM - Special Packaging (Invitrogen™)

MitoTracker® Deep Red FM is a far red-fluorescent dye (abs/em ~644/665 nm) that stains mitochondria in live cells and can be used for mitochondrial localization. The dye is well-retained after aldehyde fixation and even subsequent permeabilization with detergents.

LysoSensor™ Yellow/Blue DND-160 - Special Packaging (Invitrogen™)

LysoSensor™ Yellow/Blue DND-160 is a ratiometric probe that can be used to measure the pH of acidic organelles, such as lysosomes. The LysoSensor dye produces blue fluorescence in neutral environments, but changes to yellow fluorescence in more acidic environments. The pKa of LysoSensor Yellow/Blue DND-160 is ~4.2.

MitoTracker™ Orange CMTMRos - Special Packaging (Invitrogen™)

MitoTracker® Orange CMTMRos is an orange-fluorescent dye that stains mitochondria in live cells and its accumulation is dependent upon membrane potential. The dye is well-retained after aldehyde fixation.

LysoTracker™ Green DND-26 - Special Packaging (Invitrogen™)

LysoTracker® Green DND-26 is a green fluorescent dye that stains acidic compartments in live cells with excitation/emission maxima ~504/511 nm.

CellMask™ Deep Red Plasma membrane Stain (Invitrogen™)

The CellMask™ Plasma Membrane Stains allow fast and uniform labeling of the plasma membrane without the cell-type differences exhibited by lectins. These stains may be used as a segmentation tool for HCS (high-content screening), as well as to stain cellular plasma membranes for standard fluorescence microscopy. The stain survives fixation, but not permeabilization, so it is not suitable for experiments that also involve probing internal targets via antibodies.

ER-Tracker™ Green (BODIPY™ FL Glibenclamide), for live-cell imaging (Invitrogen™)

ER-Tracker™ Green dye is cell-permeant, live-cell stain that is highly selective for the endoplasmic reticulum (ER) that when stained using the protocol provided, the staining pattern is partially retained after fixation with formaldehyde. This stain consists of the green-fluorescent BODIPY® FL dye and glibenclamide. Glibenclamide (glyburide) binds to the sulphonylurea receptors of ATP-sensitive K+ channels which are prominent on ER; the pharmacological activity of glibenclamide could potentially affect ER function. Variable expression of sulphonylurea receptors in some specialized cell types may result in non-ER labeling.

LysoSensor™ Yellow/Blue dextran, 10,000 MW, Anionic, Fixable (Invitrogen™)

LysoSensor Yellow/Blue dextran is a ratiometric probe that can be used to measure the pH of acidic organelles, such as lysosomes. This dextran conjugate is taken up by the cells through endocytosis. The LysoSensor dye produces blue fluorescence in neutral environments, but changes to yellow fluorescence in more acidic environments. The pKa of LysoSensor Yellow/Blue dextran is ~3.9.

Yeast Mitochondrial Stain Sampler Kit (Invitrogen™)

The Yeast Mitochondrial Stain Sampler Kit contains sample quantities of five different cell-permeant probes that have been found to label mitochondria in live yeast. In addition to the well characterized mitochondrial stains rhodamine 123, and DiOC6(3), this kit includes rhodamine B hexyl ester, MitoTracker® Green FM and SYTO® 18 yeast mitochondrial stain, a proprietary green fluorescent nucleic acid stain. Each of these probes is sequestered in functioning mitochondria.

Yeast Vacuole Membrane Marker MDY-64 (Invitrogen™)

MDY-64 is a green-fluorescent yeast vacuole membrane stain.

MitoTracker™ Orange CM-H2TMRos - Special Packaging (Invitrogen™)

MitoTracker® Orange CM-H2TMRos is a reduced, nonfluorescent version of MitoTracker Orange (M-7510) that fluoresces upon oxidation. This dye also stains mitochondria in live cells and its accumulation is dependent upon membrane potential. The dye is well-retained after aldehyde fixation.