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Qdot™ 545 ITK™ Organic Quantum Dots (Invitrogen™)

Qdot® 545 ITK™ organic quantum dots are the ideal starting material for applications calling for organic solvents such as hexane, toluene, dichloromethane, or chloroform. These materials are provided as solutions in decane, and are not water soluble. These Qdot® ITK™ organic quantum dots are designed for researchers who want to use their own methods for transferring quantum dot materials into water. Our Qdot® ITK™ organic quantum dots are provided as 1 µM solutions and are available in 7 colors of Qdot® probes.

Important Features of Qdot® ITK™ Organic Quantum Dots:
• Qdot® 545 ITK™ organic quantum dot has emission maxima of ~545 nm
• Extremely photostable and bright fluorescence
• Efficiently excited with single-line excitation sources
• Narrow emission, large stokes shift
• Available in multiple colors
• Ideal for various labeling and tracking applications


Properties of Qdot® Nanocrystals
Qdot® probes are ideal for imaging and labeling applications that require bright fluorescent signals and/or real-time tracking. Unique among fluorescent reagents, all nine available colors of Qdot® probes can be simultaneously excited with a single (UV to blue-green) light source. This property makes these reagents excellent for economical and user-friendly multiplexing applications. Qdot® labels are based on semiconductor nanotechnology and are similar in scale to moderately sized proteins.

About the Innovator’s Tool Kit Qdot® ITK™ Reagents
These Qdot®ITK™ probes are ideal for researchers who wish to prepare specific (non-stocked) conjugates for their applications and need customizable conjugation functionality.

Other Forms of Qdot® Nanocrystals are Available
In addition to the organic form, we offer Qdot® ITK™ quantum dots with carboxyl and amine-derivatized PEG modifications. We’ve also developed a wide range of Qdot® nanocrystals conjugates and labeling kits. Investigate the properties of Qdot® nanocrystals or read the Molecular Probes® Handbook Section 6.6—Qdot® Nanocrystals to find out more.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Zip Alexa Fluor™ 647 Rapid Antibody Labeling Kit (Invitrogen™)

Zip Alexa Fluor Rapid Antibody Labeling kits allow you to efficiently label your precious antibody with Alexa Flour dyes to create an antibody conjugate that is ready to use within 15 minutes.

• Very fast and easy to use
• 100% antibody recovery—no purification steps
• Useful for a wide range of applications
• No chemistry or conjugation experience needed
• With an excitation and emission maximum of 650/668 nm, Alexa Fluor 647 can be efficiently excited using a 633 or 635 nm Kr or He-Ne laser line and detected under standard APC/Cy5 filters

The kit contains everything you need to perform three separate labeling reactions. Conjugates are ideal for multiple applications, including flow cytometry, fluorescent microscopy, immunohistochemistry, primary detection, ELISAs, immunocytochemistry, and indirect FISH.

Better results and workflows with labeled primary antibodies
A primary antibody directly labeled with a fluorophore often produces lower background fluorescence and less nonspecific binding. Further, multiple primary antibodies of the same isotype or derived from the same species can easily be used in the same experiment if they are directly labeled with compatible fluorophores.

Learn more about protein and antibody labeling
We offer a wide selection of Molecular Probes antibody and protein labeling kits to fit your starting material and experimental setup. See Antibody Labeling from A to Z.

Superior Alexa Fluor dyes
Compared to traditional dyes, Alexa Fluor dyes are brighter, more photostable, and more pH resistant between pH 4 and 10. And generally when using Alexa Fluor dyes, higher degrees of labeling can be achieved without intramolecular quenching. For details see Alexa Fluor Dyes Spanning the Visible and Infrared Spectrum—Section 1.3.

We'll make a custom antibody conjugate for you
If you can't find what you're looking for in our stocked list, we'll prepare a custom antibody conjugate for you. Our custom conjugation service is efficient and confidential, and we stand by the quality of our work. We are ISO 9001:2000 certified.

DiFMU (6,8-Difluoro-7-Hydroxy-4-Methylcoumarin), reference standard (Invitrogen™)

DIFMU can be used as a reference standard for ether, ester and phosphate substrates derived from this blue-fluorescent dye.

Fluorescein - Reference Standard (Invitrogen™)

Fluorescein can be used as a reference standard for ether, ester and phosphate substrates derived from this green-fluorescent dye.

Click-iT™ Plus Alexa Fluor™ 555 Picolyl Azide Toolkit (Invitrogen™)

Click-iT® Plus Alexa Fluor® picolyl azide toolkits contain everything you need to perform copper-catalyzed click reactions with compounds that are sensitive to copper, while retaining all of the benefits of the standard azide/alkyne click reaction. Picolyl azides react efficiently with chelated copper, so free copper in the click reaction can be minimized, protecting against undesired copper side reactions with proteins (e.g., GFP, RPE), nucleic acids (e.g., RNA, oligos), and even small molecules (e.g., phalloidin).

• Flexible—optimize your own Click–iT® reaction for the detection or labeling of any alkyne-containing biomolecule in vitro or in cells and tissue samples
• Bright and sensitive—superior fluorescent Alexa Fluor® dyes combined with the efficiency of picolyl azide
• Convenient—contains all the buffers and reagents needed to create the optimal click reaction

Each Click-iT® Plus Picolyl Azide Toolkit includes 100 µg of Alexa Fluor® dye-picolyl azide and all of the reagents required to create a reaction cocktail with the optimal copper and chelate concentration for any click chemistry-based labeling or detection application. Guidelines for designing and optimizing the picolyl azide/alkyne click reaction of your choice are provided in the product manual. Additionally Click-iT® Plus picolyl azides offer increased sensitivity and faster reaction times compared to standard azides using identical reaction conditions.

7-Amino-4-Methylcoumarin, reference standard (Invitrogen™)

7-Amino-4-methylcoumarin (AMC) can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates. The fluorescence spectra of AMC is not subject to variability due to pH-dependent protonation/deprotonation when assayed near or above physiological pH.

Alexa Fluor™ 594 Carboxylic Acid, tris(triethylammonium) salt (Invitrogen™)

Alexa Fluor® 594 Carboxylic Acid is a non-reactive form of Alexa Fluor® 594 that can be used as a reference standard for dye-conjugates. Additionally, this carboxylic acid derivative can be converted to an amine-reactive ester using standard chemical techniques or coupled to hydrazines, hydroxylamines, and amines in aqueous solution using water-soluble carbodiimides such as EDAC (Cat. No. E2247).

Characteristics of Alexa Fluor® 594 dye include:

• Laser line: 561 or 594 nm
• Common filter set: Texas Red
• Excitation maxima: 590 nm
• Emission maxima: 617 nm

More About Alexa Fluor® 594 Dye
Alexa Fluor® 594 dye is a bright, red-fluorescent dye that can be excited using the 561 or 594 nm laser lines. It serves as a direct replacement for Texas Red® dye with bright signal and excellent photostability, especially in fixed cells. Alexa Fluor® 594 dye is commonly used with DAPI, and Alexa Fluor® 488 and 647 dyes for multiplexing. Learn more about this dye and related products.

Discover the Benefits of the Alexa Fluor® Dye Series
Compared to traditional dyes, Alexa Fluor® dyes are brighter, more photostable, and more pH-resistant between pH 4 and 10. And generally when using Alexa Fluor® dyes, higher degrees of labeling can be achieved without intramolecular quenching. For details see Alexa Fluor® Dyes Spanning the Visible and Infrared Spectrum in the Molecular Probes Handbook.

Alexa Fluor™ 488 Carboxylic Acid, tris(triethylammonium) salt (Invitrogen™)

Alexa Fluor® 488 Carboxylic Acid is a non-reactive form of Alexa Fluor® 488 that can be used as a reference standard for dye-conjugates. Additionally, this carboxylic acid derivative can be converted to an amine-reactive ester using standard chemical techniques or coupled to hydrazines, hydroxylamines, and amines in aqueous solution using water-soluble carbodiimides such as EDAC (Cat. No. E2247).

Characteristics of Alexa Fluor® 488 dye include:

• Laser line: 488 nm
• Common filter set: FITC (fluorescein)
• Excitation maxima: 500 nm
• Emission maxima: 525 nm

More About Alexa Fluor® 488 Dye
Alexa Fluor® 488 dye is a bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line. It is the brightest and most photostable green dye for sensitive detection in live or fixed cells. Alexa Fluor® 488 dye is commonly used with DAPI, and Alexa Fluor® 594 and 647 dyes for multiplexing. Learn more about this dye and related products.

Discover the Benefits of the Alexa Fluor® Dye Series
Compared to traditional dyes, Alexa Fluor® dyes are brighter, more photostable, and more pH-resistant between pH 4 and 10. And generally when using Alexa Fluor® dyes, higher degrees of labeling can be achieved without intramolecular quenching. For details see Alexa Fluor® Dyes Spanning the Visible and Infrared Spectrum in the Molecular Probes Handbook.

Qdot™ 605 ITK™ Organic Quantum Dots (Invitrogen™)

Qdot® 605 ITK™ organic quantum dots are the ideal starting material for applications calling for organic solvents such as hexane, toluene, dichloromethane, or chloroform. These materials are provided as solutions in decane, and are not water soluble. These Qdot® ITK™ organic quantum dots are designed for researchers who want to use their own methods for transferring quantum dot materials into water. Our Qdot® ITK™ organic quantum dots are provided as 1 µM solutions and are available in 7 colors of Qdot® probes.

Important Features of Qdot® ITK™ Organic Quantum Dots:
• Qdot® 605 ITK™ organic quantum dot has emission maxima of ~605 nm
• Extremely photostable and bright fluorescence
• Efficiently excited with single-line excitation sources
• Narrow emission, large stokes shift
• Available in multiple colors
• Ideal for various labeling and tracking applications


Properties of Qdot® Nanocrystals
Qdot® probes are ideal for imaging and labeling applications that require bright fluorescent signals and/or real-time tracking. Unique among fluorescent reagents, all nine available colors of Qdot® probes can be simultaneously excited with a single (UV to blue-green) light source. This property makes these reagents excellent for economical and user-friendly multiplexing applications. Qdot® labels are based on semiconductor nanotechnology and are similar in scale to moderately sized proteins.

About the Innovator’s Tool Kit Qdot® ITK™ Reagents
These Qdot®ITK™ probes are ideal for researchers who wish to prepare specific (non-stocked) conjugates for their applications and need customizable conjugation functionality.

Other Forms of Qdot® Nanocrystals are Available
In addition to the organic form, we offer Qdot® ITK™ quantum dots with carboxyl and amine-derivatized PEG modifications. We’ve also developed a wide range of Qdot® nanocrystals conjugates and labeling kits. Investigate the properties of Qdot® nanocrystals or read the Molecular Probes® Handbook Section 6.6—Qdot® Nanocrystals to find out more.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

ROX Solution, 50 µM (Thermo Scientific™)

Thermo Scientific ROX dye is added to the qPCR reactions to serve as an internal reference for normalization of the fluorescent signal when using real-time instruments that can detect ROX. ROX allows for the correction of well-to-well variation appearing due to pipetting inaccuracies and fluorescence fluctuations. It can be added to an entire 2X master mix tube or to an individual reaction mixture (for recommended amounts of ROX Solution for a specific real-time instrument refer to the qPCR manual).

ROX does not participate in PCR and does not interfere with the specificity or sensitivity of qPCR assays.

ROX Solution contains ROX dye as a 50 µM aqueous solution at pH 7.6. The excitation maximum and emission maximum of ROX are at 580 nm and 621 nm, respectively.

Vivid™ Blue Fluorescent Standard

Vivid® Fluorescent Standards represent the products formed during oxidation of Vivid® Substrates by cytochrome P450 enzymes. These standards enable quantification of enzyme activity when used as part of the Vivid® CYP450 Screening Kits. Vivid® Fluorescent Standards are included in the Vivid® Screening Kits, but may also be purchased separately. They are supplied as a dried film.

More About Vivid® CYP450 Screening Kits
Vivid® CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition. Vivid® CYP450 Screening Kits include Vivid® Substrate, Vivid® Fluorescent Standard, reaction buffer, Vivid® Regeneration System, NADP+, and CYP450 BACULOSOMES® Plus Reagent. Vivid® Fluorogenic Substrates are blocked dyes that yield minimal fluorescence signal until cleaved or hydroxylated. Oxidation at either of two potential sites releases the highly fluorescent product. CYP450 BACULOSOMES® Plus Reagents are microsomes prepared from insect cells expressing a human CYP450 isozyme and human cytochrome P450 reductase. CYP450 BACULOSOMES® Plus Reagents offer a distinct advantage over human liver microsomes in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s.

>> View all Vivid® CYP450 Screening Kits

Applications: high-throughput screening of enzyme-drug interactions, compound profiling for drug inhibition of cytochrome P450 isozymes, generation of predictive SAR models to guide compound acquisition For Research Use Only. Not for any animal or human therapeutic or diagnostic use.

Alexa Fluor™ 647 Decapack Set (Invitrogen™)

The Alexa Fluor® 647 Reactive Dye Decapack is optimized for use with aminoallyl labeling techniques. The single-use packaging of the reactive dye eliminates the need to aliquot bulk dyes, providing convenience and ensuring maximum activity of the dyes. The specially packaged Alexa Fluor® 647 dye is compatible with both aminoallyl dUTP- and aminoallyl UTP-modified nucleotides as well as most commercially available aminoallyl-based labeling kits.

Alexa Fluor™ 488 Reactive Dye Decapack, for microarrays (Invitrogen™)

The Alexa Fluor® 488 reactive dye matches the imaging channels of most popular microarray scanners. The Alexa Fluor® reactive dye decapack is specially packaged succinimidyl ester dye for labeling of DNA or RNA samples that have been modified by incorporation of aminoallyl-dUTP (Cat. no. A21664) or aminohexylacrylamido-dUTP (Cat. no. A32761). Every packaging lot is rigorously tested for the ability to label aminoallyl-modified DNA to high and consistent levels.

Qdot™ 705 ITK™ Organic Quantum Dots (Invitrogen™)

Qdot® 705 ITK™ organic quantum dots are the ideal starting material for applications calling for organic solvents such as hexane, toluene, dichloromethane, or chloroform. These materials are provided as solutions in decane, and are not water soluble. These Qdot® ITK™ organic quantum dots are designed for researchers who want to use their own methods for transferring quantum dot materials into water. Our Qdot® ITK™ organic quantum dots are provided as 1 µM solutions and are available in 7 colors of Qdot® probes.

Important Features of Qdot® ITK™ Organic Quantum Dots:
• Qdot® 705 ITK™ organic quantum dot has emission maxima of ~705 nm
• Extremely photostable and bright fluorescence
• Efficiently excited with single-line excitation sources
• Narrow emission, large stokes shift
• Available in multiple colors
• Ideal for various labeling and tracking applications


Properties of Qdot® Nanocrystals
Qdot® probes are ideal for imaging and labeling applications that require bright fluorescent signals and/or real-time tracking. Unique among fluorescent reagents, all nine available colors of Qdot® probes can be simultaneously excited with a single (UV to blue-green) light source. This property makes these reagents excellent for economical and user-friendly multiplexing applications. Qdot® labels are based on semiconductor nanotechnology and are similar in scale to moderately sized proteins.

About the Innovator’s Tool Kit Qdot® ITK™ Reagents
These Qdot®ITK™ probes are ideal for researchers who wish to prepare specific (non-stocked) conjugates for their applications and need customizable conjugation functionality.

Other Forms of Qdot® Nanocrystals are Available
In addition to the organic form, we offer Qdot® ITK™ quantum dots with carboxyl and amine-derivatized PEG modifications. We’ve also developed a wide range of Qdot® nanocrystals conjugates and labeling kits. Investigate the properties of Qdot® nanocrystals or read the Molecular Probes® Handbook Section 6.6—Qdot® Nanocrystals to find out more.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Vivid™ Red Fluorescent Standard

Vivid® Fluorescent Standards represent the products formed during oxidation of Vivid® Substrates by cytochrome P450 enzymes. These standards enable quantification of enzyme activity when used as part of the Vivid® CYP450 Screening Kits. Vivid® Fluorescent Standards are included in the Vivid® Screening Kits, but may also be purchased separately. They are supplied as a dried film.

More About Vivid® CYP450 Screening Kits
Vivid® CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition. Vivid® CYP450 Screening Kits include Vivid® Substrate, Vivid® Fluorescent Standard, reaction buffer, Vivid® Regeneration System, NADP+, and CYP450 BACULOSOMES® Plus Reagent. Vivid® Fluorogenic Substrates are blocked dyes that yield minimal fluorescence signal until cleaved or hydroxylated. Oxidation at either of two potential sites releases the highly fluorescent product. CYP450 BACULOSOMES® Plus Reagents are microsomes prepared from insect cells expressing a human CYP450 isozyme and human cytochrome P450 reductase. CYP450 BACULOSOMES® Plus Reagents offer a distinct advantage over human liver microsomes in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s.

>> View all Vivid® CYP450 Screening Kits

Applications: high-throughput screening of enzyme-drug interactions, compound profiling for drug inhibition of cytochrome P450 isozymes, generation of predictive SAR models to guide compound acquisition For Research Use Only. Not for any animal or human therapeutic or diagnostic use.