Nucleosides and Analogues

Nucleosides and Analogues

Nucleosides and analogues are nitrogenous bases that contain a sugar and a phosphate group bonded via a covalent bond. These compounds act as cofactors in enzymatic reactions and are used in cell synthesis and cell signaling. These products include pyrimidine and purine nucleosides.
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1-15 of 72 Products

5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals Thermo Scientific Chemicals

5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to...

Brivudine, 98%, Thermo Scientific Chemicals Thermo Scientific Chemicals

It is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

2'-Deoxyguanosine monohydrate, 98+% Thermo Scientific Chemicals

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are...

Guanosine-5'-diphosphate disodium salt Thermo Scientific Chemicals

Guanosine-5'-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors.

2'-Deoxyadenosine, 99% Thermo Scientific Chemicals

2'-Deoxyadenosine is used in paradoxical stimulation study of human sperm motility. It plays an essential role as sperm motility stimulants used in sperm micro-injection on mouse and human embryo development. It finds an application in some cells as an energy source under energy stress conditions.

2-Amino-2'-deoxyadenosine, 99% Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

2'-Amino-2'-deoxyguanosine, 98% Thermo Scientific Chemicals

2‘-Amino-2‘-deoxyguanosine is a valuable probe for investigating the metal ion interactions at the active site of the group I ribozyme. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.

2'-Fluoro-2'-deoxyguanosine, 99% Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

3'-Amino-2',3'-dideoxythymidine, 99% Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

2'-Deoxycytidine Thermo Scientific Chemicals

2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?

beta-Nicotinamide adenine dinucleotide, 97%, Thermo Scientific Chemicals Thermo Scientific Chemicals

NAD+, Free Acid is a major electron acceptor molecule in biological oxidation reactions. It is also used as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling,. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product...

2'-Deoxycytidine hydrochloride, 99% Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

2'-Deoxyguanosine hydrate, 99% Thermo Scientific Chemicals

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are...

Adenosine-5'-triphosphate disodium salt hydrate, ultrapure, 98% Thermo Scientific Chemicals

Adenosine 5'-Triphosphate, is used as a p2 purinergicagonist. It is also used as a nucleotide, the 5'-triphosphate of deoxyadenosine activated precursor in DNA synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.

2',3'-Dideoxycytidine, 98+% Thermo Scientific Chemicals

2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered.
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