Nucleosides and Analogues

Nucleosides and Analogues

Nucleosides and analogues are nitrogenous bases that contain a sugar and a phosphate group bonded via a covalent bond. These compounds act as cofactors in enzymatic reactions and are used in cell synthesis and cell signaling. These products include pyrimidine and purine nucleosides.
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1-15 of 72 Products

N-Benzoyl-2'-deoxyadenosine, 98+%, Thermo Scientific Chemicals Thermo Scientific Chemicals

Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.

2',3'-Dideoxycytidine, 98+% Thermo Scientific Chemicals

2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered.

2'-Deoxyguanosine hydrate, 99% Thermo Scientific Chemicals

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are...

2'-Deoxycytidine Thermo Scientific Chemicals

2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?

2',3'-Dideoxyadenosine, 98%, Thermo Scientific Chemicals Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

8-Bromo-2'-deoxyguanosine, 99%, Thermo Scientific Chemicals Thermo Scientific Chemicals

8-Bromo-2'-deoxyguanosine is useful as the starting structure for 2'-deoxyguanosine nucleotides, which are modified in position 8. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.

2'-Fluoro-2'-deoxyinosine, 99%, Thermo Scientific Chemicals Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

3'-Deoxythymidine Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

5-Bromo-2'-deoxycytidine, 99%, Thermo Scientific Chemicals Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

2'-Fluoro-2'-deoxyadenosine, 99%, Thermo Scientific Chemicals Thermo Scientific Chemicals

2'-Fluoro-2'-deoxyadenosine is a potential prodrug for 2-fluroadenine, involves deoxygenation by reduction of the 2'-thiocar-bonylimidazolide with (Tms)3SiH as hydrogen donor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.

3'-Deoxyuridine Thermo Scientific Chemicals

A potential anti-cancer and anti-viral agent This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

2'-Fluoro-2'-deoxycytidine, 99% Thermo Scientific Chemicals

2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread.

2,2'-Diamino-2'-deoxyadenosine, 98%, Thermo Scientific Chemicals Thermo Scientific Chemicals

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

2'-Fluoro-2'-deoxyuridine, 97% Thermo Scientific Chemicals

2'-Fluoro-2'-deoxyuridine is used as a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.
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