Pyrimidine nucleosides

Pyrimidine nucleosides

Pyrimidine nucleosides are one-carbon-containing nitrogenous bases (cytosine and thymine) bonded to a ribose or deoxyribose molecule. These compounds can act as antimetabolites, extracellular messengers, and chain terminators that inhibit viral DNA polymerase.
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5-Bromo-2'-deoxyuridine, 99+% Thermo Scientific™

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

2'-Deoxyuridine, 99+% Thermo Scientific™

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

2'-Deoxyuridine, 99% Thermo Scientific™

2'-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).

Brivudine, 98%, Thermo Scientific™ Thermo Scientific™

It is used as pharmaceutical intermediate. This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

N-Benzoyl-2′-deoxycytidine, 98+%, Thermo Scientific™ Thermo Scientific™

Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine, N-Protected 2?-Deoxyribonucleosides(useful for oligonucleotide synthesis), 3?-, 5?-and 3?, 5?-di-O-crotonyl 2?-deoxynucleoside derivatives.

2',3'-Dideoxycytidine, 98+% Thermo Scientific™

2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered.

2'-Fluoro-2'-deoxycytidine, 99% Thermo Scientific™

2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread. This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio.

3'-Amino-2',3'-dideoxythymidine, 99% Thermo Scientific™

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

3'-Azido-3'-deoxythymidine, 98% Thermo Scientific™

3'-Azido-3'-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3?-Azido-3?

5-Methyl-2'-deoxycytidine, 99%, Thermo Scientific™ Thermo Scientific™

5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation. This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

2'-Fluoro-2'-deoxyuridine, 97% Thermo Scientific™

2'-Fluoro-2'-deoxyuridine is used as a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer. This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

2'-Deoxycytidine Thermo Scientific™

2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?

2'-Fluoro-2'-deoxyuridine, 97%, Thermo Scientific™ Thermo Scientific™

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo...

Thymidine, 99% Thermo Scientific™

Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology.

(+)-5-Iodo-2'-deoxyuridine, 98% Thermo Scientific™

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
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