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LentiArray™ Human Kinase CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Kinase CRISPR Library targets 822 genes with up to 4 gRNA per gene target for a total of 3,288 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Kinases are involved in almost all signaling cascades, and the dysregulation of kinase activity is linked to the development of numerous diseases, making kinases a key class of drug targets. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC), as well as additional resources, such as the KinBase database.

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Transcription Factor CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Transcription Factor Library targets 1,817 genes with up to 4 gRNA per gene target for a total of 7,268 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Transcription factors are the key regulators of gene expression. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Phosphatase CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Phosphatase Library targets 288 genes with up to 4 gRNA per gene target for a total of 1,152 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Reversible phosphorylation is a central regulatory process in signal transduction pathways. Phosphatases dephosphorylate their target proteins, are integral to the regulation of signaling pathways, and are increasingly being analyzed as potential therapeutic targets. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Nuclear Hormone Receptor CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Nuclear Hormone Receptor Library targets 47 genes with up to 4 gRNA per gene target for a total of 188 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Nuclear hormone receptors are a family of ligand-activated transcription factors that are activated by lipid-soluble ligands such as steroid hormones, thyroid hormone, vitamin D, and retinoic acid. Nuclear hormone receptors regulate a range of biological processes, including metabolism, development, proliferation, and reproduction. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Ion Channel CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Ion Channel Library targets 328 genes with up to 4 gRNA per gene target for a total of 1,312 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Ion channels are integral membrane proteins that establish the electrochemical gradient that gives rise the both the resting membrane potential and the formation of action potentials which are crucial to nerve conduction and heart and muscle contraction, as well as other processes such as insulin release and activation of T-cells. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Cancer Biology CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Cancer Biology Library targets 510 genes commonly involved in the development of cancer with up to 4 gRNA per gene target for a total of 2,040 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC), as well as The Cancer Genome Atlas (TCGA).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human DNA Damage Response CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human DNA Damage Response Library targets 561 genes with up to 4 gRNA per gene target for a total of 2,244 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

DNA surveillance proteins continuously monitor DNA integrity and activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Apoptosis CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Apoptosis Library targets 904 genes with up to 4 gRNA per gene target for a total of 3,616 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Apoptosis is a tightly regulated process that is essential for maintaining homeostasis in multicellular organisms. Inhibition of apoptosis can result in the development of cancer, autoimmune, and inflammatory disease and is involved in viral infection. Conversely, over-activation of apoptosis can lead to atrophy, tissue damage, and neurodegenerative disease. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

95401.H4POOL (yeast deletion pools) (Invitrogen™)

The Yeast Deletion Pools allow simultaneous analysis of large numbers of deletion strains through selective growth conditions. Identification and quantitation of the deletions surviving selection can be determined by hybridizing the deletions to a microarray containing all the barcode oligos (Figure 1). The barcode oligos are unique to each deletion, allowing rapid, high-throughput identification of the deletions. Each Yeast Deletion Pool contains all the deletions within the strain, equally represented within the pool. The set of Yeast Deletion Pools is supplied in five tubes, each containing 200 µl of the pooled deletions.

LentiArray™ Human Cell Surface CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Cell Surface Protein Library targets 778 genes with up to 4 gRNA per gene target for a total of 3,112 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

The broad array of cell surface proteins allows the cell to receive information from and react to its environment. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

95401.H1POOL (yeast deletion pools) (Invitrogen™)

The Yeast Deletion Pools allow simultaneous analysis of large numbers of deletion strains through selective growth conditions. Identification and quantitation of the deletions surviving selection can be determined by hybridizing the deletions to a microarray containing all the barcode oligos (Figure 1). The barcode oligos are unique to each deletion, allowing rapid, high-throughput identification of the deletions. Each Yeast Deletion Pool contains all the deletions within the strain, equally represented within the pool. The set of Yeast Deletion Pools is supplied in five tubes, each containing 200 µl of the pooled deletions.

LentiArray™ Human Epigenetics CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Epigenetics Library targets 396 genes with up to 4 gRNA per gene target for a total of 1,548 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Epigenetic regulation of gene expression plays a central role in normal development and is being recognized as a contributing factor to the development of many diseases. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human GPCR CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human GPCR Library targets 446 genes with up to 4 gRNA per gene target for a total of 1,784 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

G protein-coupled receptors (GPCRs) are regulators of a wide range of physiological and disease processes. GPCRs have emerged as one of the most druggable classes of genes, with nearly 30% of FDA approved drugs targeting GPCRs. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Membrane Trafficking CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Membrane Trafficking Library targets 141 genes with up to 4 gRNA per gene target for a total of 564 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Membrane trafficking proteins are involved in a number of processes, including neurotransmitter and endocrine release, phagocytosis, endocytosis, and lysosomal and proteosomal protein degradation. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >

LentiArray™ Human Drug Transporter CRISPR Library, Glycerol (Invitrogen™)

The award-winning Invitrogen™ LentiArray™ Human Drug Transporter Library targets 98 genes with up to 4 gRNA per gene target for a total of 392 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Transporter proteins regulate the movement of molecules across cellular membranes and play a key role in pharmacology. The gene targets within this library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Built to bring you success
LentiArray CRISPR libraries are constructed using gRNA designs produced using Thermo Fisher Scientific’s proprietary CRISPR gRNA design algorithm. This algorithm incorporates the latest gRNA design research, as well as our extensive in-house experience, to produce the highest quality designs. The gRNA designs included in the LentiArray CRISPR libraries are selected for maximal editing efficiency and specificity and are designed to knock out all known isoforms of the target gene. For each gene target, up to four high-quality gRNAs are included to help ensure highly efficient knockout of the target gene in a wide array of cell types.

Design and execute your experiments without limitations
LentiArray CRISPR libraries are designed and constructed to give you complete control over your experimental design. They utilize a two-vector design, expressing the Cas9 nuclease and the gRNA off of separate lentiviral constructs, enabling you to dictate when and how the genome editing tools are delivered to your cells.

The LentiArray Cas9 lentivirus construct expresses a human, codon-optimized Cas9 nuclease with a blasticidin-resistance gene under the control of the EF-1α (EFS) promoter. You can choose to co-infect your cells with both the LentiArray gRNA lentiviruses and the Cas9 lentivirus or just the LentiArray Cas9 lentivirus to establish a stable Cas9 expressing cell line. With LentiArray CRISPR libraries you have the freedom to design the experimental approach that best suits your model system and your screening goals.

Furthermore, to minimize restrictions to your experimental design, the gRNA lentiviruses that make up the LentiArray CRISPR libraries do not contain fluorescent markers. This allows reporters of any wavelength to be used with the libraries and expands your ability to perform multiplexed experiments. For challenging cell lines, the LentiArray gRNA lentiviruses contain a puromycin resistance gene that allows enrichment of the population of edited cells and drives stronger phenotypes.

Learn more about LentiArray CRISPR libraries >

Optimize your assay design and have full confidence in your results with LentiArray controls
High quality controls are the cornerstone of a successful screen. The LentiArray CRISPR libraries product line includes a suite of controls to help you quickly develop your assay and give you confidence in defining your hit criteria.

Learn more about LentiArray controls >