Shop All HPLC Columns

Accucore™ 150-C4 HPLC Columns Thermo Scientific™

Offer lower hydrophobic retention, ideal for optimal retention of proteins and larger peptides with Thermo Scientific™ Accucore™ 150-C4 LC Columns. Based on Core Enhanced Technology, Thermo Scientific Accucore columns provide fast, high-resolution biomolecule separations without the elevated backpressures required by sub-2μm particles.

Hypersil™ BDS Cyano HPLC Columns Thermo Scientific™

For reliable, general purpose cyano columns, choose the base-deactivated silica Thermo Scientific™ Hypersil™ BDS Cyano LC Columns. These economical columns feature reduced silanol activity and provide exceptional reliability for QA/QC labs. Built on the renowned Hypersil silica backbone, the base-deactivated silica is one of the most popular packing materials available. For more challenging separations that require improved chromatographic performance, use Thermo Scientific™ Hypersil GOLD™ Cyano LC Columns as an alternative.

Hypersil™ PREP HS Phenyl HPLC Columns Thermo Scientific™

Obtain maximum retention and loading of aromatic and moderately polar compounds with Thermo Scientific™ Hypersil™ PREP HS Phenyl reversed phase preparative HPLC columns as you scale up your method. A high surface area particle with a 100Å pore size and a phenyl bonded phase gives the stationary phase moderate hydrophobicity, making it ideal for the separation of analyte mixtures with varying polarity and aromaticity perfect for small molecule and drug purification needs.

Hypersil GOLD™ AX HPLC Columns Thermo Scientific™

Efficiently separate smaller proteins, peptides, anionic species and polar molecules with Thermo Scientific™ Hypersil GOLD™ AX LC Columns. The weak anion-exchange phase, created by a polymeric amine ligand bonded to highly pure base-deactivated silica, separates multiple charged analytes. The bonded phase offers additional chromatographic options, including hydrophilic interaction chromatography (HILIC), which is ideal for the separation of sugars and other highly polar species.

Hypersil GOLD™ Amino HPLC Columns Thermo Scientific™

Achieve excellent chromatographic separations in weak anion exchange, reversed phase and normal phase modes with Thermo Scientific™ Hypersil GOLD™ Amino LC Columns. These columns, featuring a high-performance aminopropyl phase, provide outstanding peak shape and sensitivity and are available with a 1.9μm particle size for high speed, high efficiency separations.

Acclaim™ VANQUISH™ Polar Advantage II UHPLC Columns Thermo Scientific™

Achieve even greater power of separation, speed, and throughput of polar and nonpolar compounds in a single run using Thermo Scientific™ Acclaim™ VANQUISH™ PA2 UHPLC columns. These reversed-phase columns were developed in conjunction with the Vanquish UHPLC system to take advantage of the system's extended pressure capabilities and robustness. The result is a new level of separation, speed and throughput that solve analytical challenges in liquid chromatography (LC) and LC-MS analyses. These Polar Advantage II columns provide selectivity that is complementary to conventional C18 columns.

Syncronis™ C18 Columns Thermo Scientific™

Achieve repeatable and consistent liquid chromatography (LC) separations using Thermo Scientific™ Syncronis™ C18 columns. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and ensure robust, high-resolution separations. Double end-capping provides extra surface coverage and inertness toward basic compounds. Manufactured and rigorously tested in ISO 9000 facilities, these columns are designed to meet a range of analytical needs including fast method development, quantitative analysis, and quality control.

BioBasic™ SCX HPLC Columns Thermo Scientific™

Use Thermo Scientific™ BioBasic™ SCX LC Columns for the optimized separation of proteins, peptides and other cationic species. These high-performance columns are ideal for the analysis of proteins, peptides and other biomolecules with higher efficiency than polymeric ion exchange.

Acclaim™ Polar Advantage II HPLC Columns Thermo Scientific™

Resolve polar and nonpolar compounds in a single run with Thermo Scientific™ Acclaim™ PolarAdvantage II (PA2) reversed-phase columns. These high-efficiency, silica-based columns have a polar-embedded stationary phase that operates over a wider range of chromatographic conditions than possible with conventional reversed-phase stationary phases. Its unique chemistry provides enhanced hydrolytic stability from pH 1.5 to 10 with 100% aqueous mobile phases. The column exhibits selectivity that is complementary to conventional C18 columns and excellent peak shapes for both basic and acidic compounds.

Accucore™ 150 C18 HPLC Columns Thermo Scientific™

Offer phase characteristics designed for the separation of peptides with Thermo Scientific™ Accucore™ 150 C18 LC Columns. Based on Core Enhanced Technology, Accucore columns provide fast, high-resolution biomolecule separations without the elevated backpressures required by sub-2μm particles.

Syncronis™ Silica HPLC Columns Thermo Scientific™

Optimize the reproducibility of normal phase chromatographic separations using Thermo Scientific™ Syncronis™ Silica LC Columns. Highly pure, base-deactivated, high surface area silica media ensure robust, high-resolution separations of nonpolar and moderately polar organic compounds by normal phase chromatography. Manufactured and rigorously tested in ISO 9000 facilities, these columns are designed to meet a range of analytical needs including fast method development, quantitative analysis and quality control.

AccucoreTM Biphenyl Reversed Phase HPLC Columns

Choose Thermo Scientific™ Accucore™ Biphenyl LC Columns for fast and reliable separation of critical pairs and isomers. These columns provide unique selectivity for aromatic and moderately polar analytes. Their optimized packing offers a rugged platform for a variety of matrices. Based on Core Enhanced Technology, Accucore liquid chromatography reversed phase columns provide fast, high-resolution separations without the elevated backpressures seen using sub-2µm particles.

  • Fast separations with excellent resolution and sensitivity
  • Lower backpressures so that UHPLC is not required
  • Mixed-mode selectivity for aromatic and moderately polar analytes
  • Enhanced Pi-pi interactions with aromatics
  • Excellent lot-to-lot reproducibility

Syncronis™ C18 HPLC Columns Thermo Scientific™

Attain repeatable and consistent LC separations for your scale up purification needs with Thermo Scientific™ Syncronis™ C18 reversed phase preparative HPLC columns. These preparative HPLC columns have extremely pure, high surface area silica with dense stationary phase coverage to minimize secondary interactions and ensure robust, high-resolution separations. Double endcapping provides additional surface coverage and inertness toward basic compounds. Columns come in a variety of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.

GlycanPac™ AXH-1 HPLC Columns Thermo Scientific™

Use Thermo Scientific™ GlycanPac™ AXH-1 LC Columns for qualitative, quantitative, and structural characterization of uncharged and charged glycans present in biological molecules. This high-performance, silica-based high-performance liquid chromatography (HPLC) column provides simultaneous separation of glycans by charge, size and polarity. Achieve high-resolution and high-throughput analysis with unique selectivity for biologically important glycans, either labeled or native, by LC-fluorescence and LC-mass spectrometry (MS) methods.

Hypersil™ PREP BDS C18 HPLC Columns Thermo Scientific™

Easily scale up your analytical method using Thermo Scientific™ Hypersil™ PREP BDS C18 reversed phase preparative HPLC Columns. Our prep columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. These endcapped, silica-based columns offer C18 retention with base deactivation for reduced silanol activity and are an excellent choices for routine applications which require development from analytical to preparative LC scale.

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