Shop All Antibiotics

Gentamicin (10 mg/mL) Gibco™

Gentamicin sulfate is a water-soluble antibiotic drug originally purified from the fungus Micromonospora purpurea. Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition protein synthesis and death in susceptible bacteria. Gibco® Gentamicin is effective against a wide variety of gram-positive and gram-negative bacteria, and is used for the prevention of bacterial contamination on cell cultures. The recommended working concentration ranges from 0.5 to 50 µg/ml. We offer a variety of antibiotics and antimycotics for cell culture applications.

Product Use
For Research Use Only: Not intended for animal or human diagnostic or therapeutic use.

Dual-Site cGMP Manufacturing
Gibco® Gentamicin is manufactured at a cGMP compliant facility, located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standards. For supply chain continuity, we offer a comparable Gibco® Gentamicin product made in our Scotland facility (15710-049). This facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standard.

Ampicillin, sodium salt, irradiated Gibco™

Ampicillin is an antibiotic in the broad-spectrum penicillin group. Ampicillin differs from penicillin only by the presence of an amino group, which facilitates penetration through the outer membrane of some gram-negative bacteria. Ampicillin acts by interfering directly with the turnover of the bacterial cell wall and indirectly by triggering the release of enzymes that further alter the cell wall.

Gibco Ampicillin is used as a selective antibiotic generally at a concentration of 20–125 µg/mL. Ampicillin selection is based on hydrolysis and inactivation of its beta-lactam ring by beta-lactamase expressed by the bla gene. Sometimes, beta-lactamase produced by the bacteria is secreted into the medium resulting in inactivation of ampicillin in the culture medium. Ampicillin degradation on agar plates can lead to the formation of satellite colonies. Growth of these colonies can be halted by adding fresh ampicillin. To avoid beta-lactamase buildup, special care must be taken while handling cultures and determining the correct dose of antibiotic.

Ampicillin antibiotic in powder form is an economical choice that can be used in a wide range of gram-positive and gram-negative infections. This product is provided as a powder and should be made into a stock solution at a concentration of 10 mg/mL in water.

cGMP manufacturing
Gibco Ampicillin is manufactured at a cGMP compliant facility located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standards.

Zeocin™ Selection Reagent Gibco™

Gibco® Zeocin™ Selection Antibiotic is a formulation of phleomycin D1, a glycopeptide antibiotic produced by Streptomyces verticillus. Zeocin™ Selection Antibiotic acts by binding to and cleaving DNA, leading to cell death.

Zeocin™ Selection Antibiotic is used for selection of of mammalian, insect, yeast, bacterial, and plant cell cultures. It is used at a working concentration ranging between 50–400 µg/mL depending on the cell type. This product is supplied at 100 mg/mL in sterile water in one 50 mL bottle.

Other Choices and More Information
We offer a wide range of antibiotics and antimycotics in both powder and liquid formats.

See the complete list, or find products for:
Contamination control
Eukaryotic and bacterial selection

See recommendations for working concentrations for selection antibiotics.

Learn more about the use of antibiotics and antimycotics in cell culture, and review guidelines for decontaminating cultures.

Zeocin is a trademark of Invivogen.

Kanamycin Sulfate Gibco™

Kanamycin Sulfate is a water-soluble antibiotic originally purified from the bacterium Streptomyces kanamyceticus. Kanamycin acts by binding to the 30S subunit of the bacterial ribosome and inhibiting protein synthesis in susceptible bacteria. Gibco® Kanamycin is effective against a wide variety of gram-negative and some gram-positive bacteria, and is used for the prevention of bacterial contamination of cell cultures. We offer a variety of antibiotics and antimycotics for cell culture applications.

Product Use
For Research Use Only: Not intended for animal or human diagnostic or therapeutic use.

Dual-Site cGMP Manufacturing
For supply chain continuity, we manufacture Gibco® Kanamycin at two separate facilities located in Grand Island, NY and Scotland, UK. Both sites are compliant with cGMP manufacturing requirements, are certified to ISO 13485, and are registered with the FDA as medical device manufacturers.

Polymyxin B Sulfate Gibco™

Polymyxin B Sulfate is produced by Bacillus polymyxa. Polymyxin B Sulfate works by binding to the cellular membrane and interfering with its permeability. Gibco® Polymyxin B Sulfate is used for the prevention of bacterial contamination of cell cultures. This antibiotic is highly active against gram-negative bacteria. The recommended working concentration is 100 units/ml. We offer a variety of antibiotics and antimycotics for cell culture applications.

Product Use
For Research Use Only: Not intended for animal or human diagnostic or therapeutic use.

Gentamicin (50 mg/mL) Gibco™

Gentamicin sulfate is a water-soluble antibiotic originally purified from the fungus Micromonospora purpurea. Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria. Gibco® Gentamicin is effective against a wide variety of gram-positive and gram-negative bacteria, and is used to prevent the contamination of cell cultures by bacteria. The recommended working concentration ranges from 0.5 to 50 µg /mL.

We offer a wide range of antibiotics and antimycotics in both powder and liquid formats.

Learn more about the use of antibiotics and antimycotics in cell culture and review guidelines for decontaminating cultures.

Dual-Site cGMP Manufacturing
Gibco® Gentamicin is manufactured at a cGMP compliant facility, located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standards. For supply chain continuity, we offer a comparable Gibco® Gentamicin product made in our Scotland facility (15750-037). This facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standard.

Penicillin-Streptomycin (10,000 U/mL) Gibco™

This solution contains 10,000 units/mL of penicillin and 10,000 µg/mL of streptomycin. The antibiotics penicillin and streptomycin are used to prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteria. Penicillin was originally purified from the fungi Penicillium and acts by interfering directly with the turnover of the bacterial cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus. It acts by binding to the 30S subunit of the bacterial ribosome, leading to inhibition of protein synthesis and death in susceptible bacteria.

We offer a wide range of antibiotics and antimycotics in both powder and liquid formats. Learn more about the following types of products:

Cell Culture Antibiotics
Selection Antibiotics (including recommended working concentrations)

Learn more about the use of antibiotics and antimycotics in cell culture and review guidelines for decontaminating cultures.

Actinomycin D Gibco™

Actinomycin D is a nonfluorescent DNA intercalator that exhibits high GC selectivity and causes distortion at its binding site. Binding of the nonfluorescent actinomycin D to nucleic acids changes the absorbance of the dye. Actinomycin D has been used for chromosome banding studies.

Amphotericin B Gibco™

Amphotericin B is the generic version of Fungizone. 'Fungizone' is a trademark of E.R. Squibb & Sons, LLC. Amphotericin B is an antifungal, produced by Streptomyces nodosus. It prevents the growth of fungi by causing an increase in fungal plasma membrane permeability. It actively binds to sterols and leads to the formation of pores. It is used to prevent the contamination of cell cultures by yeast and multicellular fungi. Gibco Amphotericin B contains 250 µg of amphotericin B and 205 µg of sodium deoxycholate per mL of distilled water. The recommended working concentration ranges from 0.25 to 2.50 µg/mL.

Dual-site cGMP manufacturing
For supply chain continuity, we manufacture Gibco Amphotericin B at two separate facilities located in Grand Island, NY and Scotland, UK. Both sites are compliant with cGMP manufacturing requirements, are certified to the ISO 13485 standard, and are registered with the FDA as medical device manufacturers.

Neomycin Sulfate Gibco™

Gibco® Neomycin is produced by Streptomyces fradiae. Polymyxin B Sulfate acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria. Gibco® Neomycin Sulfate is used for the prevention of bacterial contamination of cell cultures. This antibiotic is highly active against gram-negative bacteria. The recommended working concentration is 50 µg/ml. We offer a variety of antibiotics and antimycotics for cell culture applications.

Product Use
For Research Use Only: Not intended for animal or human diagnostic or therapeutic use.

Carbenicillin Disodium Salt Gibco™

Carbenicillin Disodium Salt is a semi-synthetic penicillin antibiotic with a carboxyl and benzyl group. Its mechanism of action is the same as ampicillin. It interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity to plant tissues. Gibco Carbenicillin is used as a selective antibiotic for resistant agrobacterium and E. coli, generally at a concentration of 50–100 µg/mL. The β-lactamase (bla) gene, which confers resistance to ampicillin, also confers resistance to carbenicillin. It is broken down more slowly by beta-lactamase compared to ampicillin, thus is more stable. It can reduce the growth of satellite colonies during long-term incubations. This product is provided as a powder and should be made into a stock solution of 50–100 mg/mL in water.

Penicillin-Streptomycin (5,000 U/mL) Gibco™

The antibiotics penicillin and streptomycin are used to prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteria. Penicillin was originally purified from the fungi Penicillium and acts by interfering directly with the turnover of the bacterial cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus. It acts by binding to the 30S subunit of the bacterial ribosome, leading to inhibition of protein synthesis and death in susceptible bacteria. This solution contains 5000 units/mL of penicillin and 5000 µg/mL of streptomycin.

We offer a wide range of antibiotics and antimycotics in both powder and liquid formats. See the complete list, or find products for:

Contamination control
Eukaryotic and bacterial selection

See recommended working concentrations for selection antibiotics.

Learn more about the use of antibiotics and antimycotics in cell culture and review guidelines for decontaminating cultures.

Puromycin Dihydrochloride Gibco™

Puromycin Dihydrochloride is an aminonucleoside antibiotic produced by Streptomyces alboniger. Puromycin works by inhibiting peptidyl transfer on both prokaryotic and eukaryotic ribosomes; resistance is conferred by the expression of the pac gene.

Puromycin is widely used in cell biology as a selection antibiotic agent in mammalian cell culture systems. The recommended working concentration ranges from 0.2–5.0 µg/mL, although it can be toxic to eukaryotic cells at concentrations as low as 1 µg/mL. Gibco® Puromycin Dihydrochloride is supplied at 10 mg/mL in 20 mM HEPES buffer (pH 6.2–6.8) in 10 vials each containing 1 mL.

Other Choices and More Information
We offer a wide range of antibiotics and antimycotics in both powder and liquid formats.

See the complete list, or find products for:
Contamination control
Eukaryotic and bacterial selection

See recommendations for working concentrations for selection antibiotics.

Learn more about the use of antibiotics and antimycotics in cell culture, and review guidelines for decontaminating cultures.

Antibiotic-Antimycotic (100X) Gibco™

Gibco® Antibiotic-Antimycotic is used to prevent bacterial and fungal contamination. This solution contains 10,000 units/mL of penicillin, 10,000 µg/mL of streptomycin, and 25 µg/mL of Gibco Amphotericin B. The antibiotics penicillin and streptomycin prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteria. Amphotericin B prevents fungal contamination of cell cultures due to its inhibition of multi-cellular fungus and yeast.

Penicillin was originally purified from the fungus Penicillium and acts by interfering directly with the turnover of the bacteria cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus. It acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria. Amphotericin B is an antifungal agent that prevents the growth of fungi and yeast by causing an increase in fungal plasma membrane permeability.

Penicillin-Streptomycin-Neomycin (PSN) Antibiotic Mixture Gibco™

The antibiotics Penicillin, Streptomycin, and Neomycin are used to prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteria. Penicillin was originally purified from the fungus Penicillium and acts by interfering directly with the turnover of the bacteria cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus and Neomycin from Streptomyces fradiae. Streptomycin and Neomycin act by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria. We offer a variety of antibiotics and antimycotics for cell culture applications.

This solution contains 5 mg of penicillin, 5 mg of streptomycin, and 10 mg of neomycin per ml in 0.85% saline.

Product Use
For Research Use Only: Not intended for animal or human diagnostic or therapeutic use.
Results per page
    spinner