Shop All Cellular Imaging

Celleste™ 5 3D Analysis Module, for network Invitrogen™

Celleste 5.0 Image Analysis Software is a suite of image analysis and visualization tools designed for a range of biological applications that lets you transform your images into quantitative data in a streamlined and customizable workflow. Coupled with the powerful image acquisition capabilities of our EVOS microscopes, Celleste 5 software allows you to seamlessly capture, process, measure, analyze, and share images and data. Optional modules for 2D and 3D deconvolution, visualization, and analysis allow you to customize the capabilities according to your needs. This Celleste 5 3D Analysis Module helps visualize complex 3D objects using guided segmentation designed to facilitate identification and measurements. This version of the module is for owners of a network server license for Celleste 5.0 Image Analysis Software.

Celleste 5.0 software with the 3D Analysis Module offers you these important advantages:
• Streamlined workflow tools that make it easy to visualize and edit images
• Powerful image analysis capabilities for segmentation, classification, and quantification of single images or a batch of images
• Automatic segmentation of objects using any 2D frame in the Z-stack
• Seamless propagation t in Z with automated or semi-automated tools
• Automatic generation of iso-surfaces and pseudo-surfaces
• 3D counting, including co-localization
• Measurement of point-to-point distances, surfaces, and volumes

More about the deconvolution modules
Deconvolution is an algorithm-based process used to restore systematic loss of image contrast (blur) that results from the image point spread function (PSF). The powerful 2D and 3D restoration algorithms available in the Celleste 5 modules allow you to deconvolve your images to enhance contrast and quality, or to visualize them in Z, over time and by channel, then analyze the resulting image using an expanded tool set.

EVOS™ Vessel Holder for Oil Objectives, one 25 x 75 mm microscope slide Invitrogen™

EVOS vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS imaging systems for increased precision in sample alignment. This particular vessel holder securely holds one 25 mm x 75 mm microscope slide is designed to provide the greater clearance needed when using oil objectives. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of vessel holders convenient and easy.

For additional choices, see the EVOS Guide to Vessel Holders and Stage Plates.
Explore the entire EVOS line of imaging systems and accessories.

Zeiss 63X Objective, LD Plan-Neofluar (0.75 NA) Thermo Scientific™

The Zeiss™ 63x (0.75NA) LD Plan-Neofluar objective lens for the Thermo Scientific™ ArrayScan™ HCA Readers is made by the world renowned optics company, Zeiss. The Zeiss 63X (0.75NA) LD Plan-Neofluar lens represents the finest in optical with a magnification power suited for subcellular imaging, and a numerical aperture which strikes a balance between resolution and versatility.

ViewRNA 440µL Thermo Scientific™

ViewRNA 440µL

Celleste™ 5 GPU Acceleration Module, for network Invitrogen™

Celleste 5.0 Image Analysis Software is a suite of image analysis and visualization tools designed for a range of biological applications that lets you transform your images into quantitative data in a streamlined and customizable workflow. Coupled with the powerful image acquisition capabilities of our EVOS microscopes, Celleste 5 software allows you to seamlessly capture, process, measure, analyze, and share images and data. Optional modules for 2D and 3D deconvolution, visualization, and analysis allow you to customize the capabilities according to your needs. This Celleste 5 GPU Acceleration Module helps perform 3D deconvolution and analysis in a fraction of the time by utilizing the graphics processing unit (GPU) of your EVOS PC or workstation. It also helps enable the processing of thousands of voxels at once for faster processing speed, increased performance, and better response times. This version of the module is for owners of a network server license for Celleste 5.0 Image Analysis Software.

Celleste 5.0 software with the GPU Acceleration Module offers you these important advantages:
• Streamlined workflow tools that make it easy to visualize and edit images
• Powerful image analysis capabilities for segmentation, classification, and quantification of single images or a batch of images
• GPU-accelerated deconvolution to increase performance and reduce the time to results
• Clear images in a fraction of the time with CPU-based processing

More about the deconvolution modules
Deconvolution is an algorithm-based process used to restore systematic loss of image contrast (blur) that results from the image point spread function (PSF). The powerful 2D and 3D restoration algorithms available in the Celleste 5 modules allow you to deconvolve your images to enhance contrast and quality, or to visualize them in Z, over time and by channel, then analyze the resulting image using an expanded tool set.

EVOS™ Vessel Holder for Automated Stage, one Terasaki plate Invitrogen™

EVOS vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS imaging systems for increased precision in sample alignment. This particular vessel holder securely holds one Terasaki plate and is specific for the automated stage of the EVOS FL Auto Imaging System. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of vessel holders convenient and easy.

For additional choices, see the EVOS Guide to Vessel Holders and Stage Plates.
Explore the entire EVOS line of imaging systems and accessories.

ArrayScan™ 7-Color LED Module for ArrayScan™ HCA Readers Thermo Scientific™

The Thermo Scientific™ ArrayScan™ 7-Color LED Module for ArrayScan™ HCA Readers (600-800 series) is a seven color, direct coupled, Light Emitting Diode (LED) light source designed for high performance and ultra-reliability to excite fluorochromes that are blue, cyan, green, yellow, orange-red, scarlet, far red, and near IR.

Features of the ArrayScan 7-Color LED Module for ArrayScan HCA Readers:

• Spectral flexibility—spanning the visible spectrum from UV through near-IR, the ArrayScan 7-Color LED Module can use the available filter combinations to provide for a multitude of excitation and emission combinations
• Spectral separation—avoid bleed through between channels by using excitation and emission wavelengths that have bands separated enough to prevent spectral overlap

Includes:

• To be used with Thermo Scientific™ HCS Studio™ Cell Analysis Software (version 2.0 or greater) and minimum computer specifications
• Filters and emission filter wheel

EVOS™ Stage Plate, 160 x 110 mm opening

This EVOS stage plate is intended for use on the stage of the EVOS XL, FL, and FL Color imaging systems. This stage plate has a 160 x 110 mm opening that accomodates the EVOS Stage Plate Adapter. The adapter is designed to hold a range of EVOS vessel holders. This stage plate includes mounting hardware and is just one of many easy-to-change stage plates and vessel holders available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of vessel holders convenient and easy.

For additional choices, see the EVOS Guide to Vessel Holders and Stage Plates.
Explore the entire EVOS line of imaging systems and accessories.

HCS Studio™ 2.0 Cell Analysis Software, client installation Thermo Scientific™

Thermo Scientific™ HCS Studio™ 2.0 Cell Analysis Software is the engine behind Thermo Scientific™ High Content Products. HCS Studio 2.0 Cell Analysis Software allows access to all instrument configuration and control functions with software-resident protocols that provide visual feedback to enable custom assay protocol setup, image acquisition, analysis, and data visualization. HCS Studio 2.0 Cell Analysis Software works in concert with Thermo Scientific Store™ Image and Database Management Software to analyze and store the resulting high content images and data.

Features of HCS Studio 2.0 Cell Analysis Software:

• Protocol Creation—Assay protocols can be created from pre-configured templates or completely by the user. After image acquisition and analysis have been performed, data can be stored at the cell–, field–, and well–levels.
• Online Phenotyping—Cells can be identified and separated based on features selected by the user. Appropriate numbers of cells can then be analyzed within the phenotypic parameters.
• Analysis of Multiple Image Formats—Allows image formats from a variety of sources and in several different image formats to be imported, analyzed, and compared to cell data acquired locally, and stored using the Store Image and Database Management Software.
• Comparison and Optimization of Two Biological Extents—Allows the user to eliminate user bias from analyses when more than one cell type is being interrogated.

HCS Studio 2.0 Cell Analysis Software Capabilities:

• HCS Studio 2.0 Cell Analysis Software expertly balances flexibility with ease-of-use through intuitive interfaces, intelligent design and powerful image analysis tools leading to meaningful dynamic measurements at the cell-, field-, and well- levels.
• Task Oriented Approach—Straightforward workflow and >30 pre-configured assays allows a new user to generate meaningful data almost immediately.
• Seamless Scale-up—Experienced users will find numerous tools and help functions to allow for the development of custom assay protocols and visualizations.

Software:

• The Thermo Scientific™ HCS Studio™ Navigator Application is the launching point for Assay Development (configuration, population characterization, data selection), Instrument Control, Data Visualization, and Image/Data Portability.
• The Thermo Scientific™ HCS Studio™ Scan Application controls both image acquisition and image analysis including the variables for data generation (imaging parameters, algorithm setting, population identification, selective data storage, and sample identification) for efficient retrieval from the database.
• All in an intuitive package that is workflow–oriented and contains sufficient preconfigured functionalities that the novice can use straight away but allows the experienced user to find sufficient flexibility to keep it challenging while maintaining the quality of data produced.

EVOS™ XL Core Configured Cell Imager Invitrogen™

The EVOS XL Core Imaging System is a digital transmitted-light inverted imaging system for cell and tissue culture applications and routine cell maintenance. Its simple user interface drives a color camera and high-quality optical system that delivers high-definition images with exceptional ease. Equipped with 4X, 10X, and 20X long working distance (LWD) phase contrast (PH) objectives, the all-in-one EVOS XL Core system is an ideal microscope for basic imaging needs. With a small footprint, an articulated monitor, and ergonomic design, it is a perfect addition to any cell culture room or facility.

The EVOS XL Core Imaging System offers these important advantages:
• Easy installation; no maintenance, assembly, alignment, or calibration
• 4X, 10X, and 20X LWD PH objectives that are ideal for tissue culture microscopy
• A fixed stage for flexibility in imaging different cell culture vessels
• Fits and operates inside cell culture hoods
• All-in-one design: digital camera, precision optics, LCD display, and USB storage

Imaging anywhere
The EVOS XL Core system is an integrated transmitted-light inverted imaging system that combines high-quality optics, a 12.1-inch high-resolution LCD display, and a digital color camera. Images are seamlessly acquired through the user interface using a mouse and the integrated software that includes a variety of features, such as color temperature control. All images can be saved onto the USB device in JPEG, BMP, or TIFF formats. Applications suited for the EVOS XL Core system include basic imaging of live and fixed cells, tissue culture needs (confluence, density, and growth), stem cell isolation, and analysis of stained tissue slices.

The EVOS imaging systems are built from the ground up to maximize performance and optimize workflow. You will be astonished at how easy this system is to operate and amazed how good your images look.

Versatile
While the microscope comes equipped with three objectives (4X, 10X, and 20X LWD PH), the four-position objective turret can be configured to meet additional needs using our full range of LWD phase contrast and coverslip-corrected objectives. LWD PH objectives are available from 1.25X to 40X. The compact footprint makes it easy to use the EVOS XL Core system wherever needed; the entire system can be easily moved into a cell culture hood or glove box. The universal stage provides maximum flexibility for slides, culture dishes, and flasks. An optional mechanical stage affords more precise handling and positioning of multi-well plate vessels.

Easy to use and reliable
The EVOS XL Core Imaging System is plug-and-play. In addition to an exceptionally easy set-up and installation, it requires no warm-up or cool-down periods. The LED light source offers exceptional stability and durability--so you can turn the unit on and off whenever you need to image a sample. The LED bulbs are rated for >50,000 hours (~17 years), compared to 300 hours for a typical mercury bulb and 1,500 hours for a metal halide bulb. The long lifetime and low energy consumption translate into lower operating costs compared to instruments with conventional light sources. Finally, the advanced ergonomic design of the EVOS systems removes the strain of conventional microscopes in imaging, enables shared viewing, and makes moving the units easy.

Olympus™ 4X Objective, U Plan S-Apo, 0.16 NA Thermo Scientific™

The Olympus 4X (0.16NA) U Plan S-Apo objective lens is suitable for use with the Thermo Scientific CellInsight CX5, CX7 LED, and CX7 LZR high content screening (HCS) platforms. It has a magnification power suited for subcellular imaging and a numerical aperture which strikes a balance between resolution and versatility.

X1 Upgrade for ArrayScan™ VTI HCS Reader Thermo Scientific™

The Thermo Scientific™ X1 Upgrade ArrayScan™ VTI HCS Reader takes a current Thermo Scientific ArrayScan™ VTI HCS Reader (600 and 700 series) up to the latest image capture technology with the new X1 large field of view camera and. The Photometrics X1 CCD camera boasts a 14-bit dynamic range; 2208x2208 pixel array; 4.54 micron pixel size; and 75% peak Quantum Efficiency (QE) to provide high resolution images to the Thermo Scientific™ HCS Studio™ Cell Analysis Software, and ultimately to a relational database for secure storage and access.

Features of the X1 Upgrade for ArrayScan VTI HCS Reader:

• High sensitivity—By harnessing the photon-collecting power of the Sony™ SuperHAD microlens architecture, the X1 camera becomes ultra-sensitive without sacrificing resolution (4.5µm/pixel).
• See more in every image—The cutting-edge Photometrics X1 CCD camera with the enlarged field of view and 4.54 μm pixel size.
• Hardware designed for high throughput—Processing of the data and images from the X1 camera is optimized with a powerful Windows 7, 64-bit PC with a quad core processor.
• HCS Studio™ Cell Analysis Software is the integrated instrument control, visualization and analysis software package for novice to advanced users.
• Features Thermo Scientific™ Store Express Image and Database Software using a 10GB SQL™ database

Key Technological Features:

• High-resolution, thermo-electrically cooled to 0°C; 14-bit dynamic range; 2208x2208 pixel array; 4.54 micron pixel size; 75% peak Quantum Efficiency (QE); USB 2.0 (no additional CameraLink or FireWire Cards needed); 1x1, 2x2 or 4x4 binning options
• Binning option applied before digitization, which reduces read noise and provides for a 4:1 signal-to-noise ratio
• Larger imaging chip (2208 x 2208 px.)
• Sony SuperHAD microlens architecture for light collection
• Windows 7 Professional 64Bit Cube Computer with minimum quad core 3.7 GHz processor, 32GB RAM, and 500GB Hard Drive space for local images and data for instrument

Coverglass Removal Tool Invitrogen™

The Coverglass Removal Tool is intended for use with a CultureWell™ Chambered Coverglass for Cell Culture (Cat. Nos. C37000, C37005). This tool enables you to easily separate the chambered upper structure from the coverglass without the need for excessive force, minimizing the risk of coverglass breakage.

Celleste™ 5 2D Blind/Non-Blind Deconvolution Module Invitrogen™

Celleste 5.0 Image Analysis Software is a suite of image analysis and visualization tools designed for a range of biological applications that lets you transform your images into quantitative data in a streamlined and customizable workflow. Coupled with the powerful image acquisition capabilities of our EVOS microscopes, Celleste 5 software allows you to seamlessly capture, process, measure, analyze, and share images and data. Optional modules for 2D and 3D deconvolution, visualization, and analysis allow you to customize the capabilities according to your needs. This Celleste 5 2D Blind/Non-Blind Deconvolution Module helps improve single-plane image quality (S/N) of cells or tissue slices by clearing background haze (out-of-focus light).

Celleste 5.0 software with this 2D Blind/Non-Blind Deconvolution Module offers you these important advantages:
• Streamlined workflow tools that make it easy to visualize and edit images
• Powerful image analysis capabilities for segmentation, classification, and quantification of single images or a batch of images
• Blind and non-blind deconvolution options
• Dramatically improved image quality
• Removal of blur that can obscure important details
• The tools to generate more impressive images and reliable data

More about the deconvolution modules
Deconvolution is an algorithm-based process used to restore systematic loss of image contrast (blur) that results from the image point spread function (PSF). The powerful 2D and 3D restoration algorithms available in the Celleste 5 modules allow you to deconvolve your images to enhance contrast and quality, or to visualize them in Z, over time and by channel, then analyze the resulting image using an expanded tool set.

Celleste™ 5 3D Analysis Module Invitrogen™

Celleste 5.0 Image Analysis Software is a suite of image analysis and visualization tools designed for a range of biological applications that lets you transform your images into quantitative data in a streamlined and customizable workflow. Coupled with the powerful image acquisition capabilities of our EVOS microscopes, Celleste 5 software allows you to seamlessly capture, process, measure, analyze, and share images and data. Optional modules for 2D and 3D deconvolution, visualization, and analysis allow you to customize the capabilities according to your needs. This Celleste 5 3D Analysis Module helps visualize complex 3D objects using guided segmentation designed to facilitate identification and measurements.

Celleste 5.0 software with the 3D Analysis Module offers you these important advantages:
• Streamlined workflow tools that make it easy to visualize and edit images
• Powerful image analysis capabilities for segmentation, classification, and quantification of single images or a batch of images
• Automatic segmentation of objects using any 2D frame in the Z-stack
• Seamless propagation t in Z with automated or semi-automated tools
• Automatic generation of iso-surfaces and pseudo-surfaces
• 3D counting, including co-localization
• Measurement of point-to-point distances, surfaces, and volumes

More about the deconvolution modules
Deconvolution is an algorithm-based process used to restore systematic loss of image contrast (blur) that results from the image point spread function (PSF). The powerful 2D and 3D restoration algorithms available in the Celleste 5 modules allow you to deconvolve your images to enhance contrast and quality, or to visualize them in Z, over time and by channel, then analyze the resulting image using an expanded tool set.

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