Crosslinking Reagents

Crosslinking Reagents

Crosslinking reagents contain reactive end groups that respond to the presence of specific functional groups by forming bonds between polymer chains. These products include crosslinking reagents ideal for various applications, including conjugation reactions, biomolecule labeling, and molecular purification.
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1-15 of 91 Products

EZ-Link™ Biotin-PEG12-DBCO Thermo Scientific™

EZ-Link Biotin-PEG12-DBCO is a biotinylation reagent that contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry attachment to an azide-labeled molecule, enabling the attachment of biotin using a bioorthogonal approach.

Pierce™ SM(PEG)12, No-Weigh™ Format Thermo Scientific™

Thermo Scientific Pierce SM(PEG)12 is a hetero-bifunctional crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules.

BS(PEG)9 (PEGylated bis(sulfosuccinimidyl)suberate) Thermo Scientific™

BS(PEG)9 is a bis-succinimide ester-activated PEG compound used for crosslinking between primary amines (—NH2) in proteins and other molecules. The N-hydroxysuccinimide ester (NHS) groups at either end of the PEG9 spacer react specifically and efficiently with lysine and N-terminal amino groups at...

SM(PEG)6 (PEGylated, long-chain SMCC crosslinker) Thermo Scientific™

Thermo Scientific Pierce SM(PEG)n is a series of amine-to-sulfhydryl crosslinkers that differ in length from 17.6 to 95.2 angstroms as a result of polyethylene glycol spacer arms containing n equals 2 to 24 ethylene glycol units.

SM(PEG)24 (PEGylated, long-chain SMCC crosslinker) Thermo Scientific™

Thermo Scientific Pierce SM(PEG)n is a series of amine-to-sulfhydryl crosslinkers that differ in length from 17.6 to 95.2 angstroms as a result of polyethylene glycol spacer arms containing n equals 2 to 24 ethylene glycol units.

SM(PEG)12 (PEGylated, long-chain SMCC crosslinker) Thermo Scientific™

Thermo Scientific Pierce SM(PEG)n is a series of amine-to-sulfhydryl crosslinkers that differ in length from 17.6 to 95.2 angstroms as a result of polyethylene glycol spacer arms containing n equals 2 to 24 ethylene glycol units.

PEG12-SPDP (PEGylated, long-chain SPDP crosslinker) Thermo Scientific™

Thermo Scientific Pierce PEG12-SPDP is a multifunctional crosslinker for protein conjugation via amine-to-amine or amine-to-sulfhydryl crosslinks that contain a 12-unit polyethylene glycol (PEG) group and a reducible (cleavable) disulfide bond.

EZ-Link™ TFP Ester-PEG12-DBCO Thermo Scientific™

EZ-Link TFP Ester-PEG12-DBCO is a hetero-bifunctional crosslinker that contains an amine-reactive tetrafluorophenyl (TFP) group and a dibenzylcyclooctyne (DBCO) group with a water-solubilizing long PEG12 spacer in between.

SM(PEG)8 (PEGylated, long-chain SMCC crosslinker) Thermo Scientific™

Thermo Scientific Pierce SM(PEG)n is a series of amine-to-sulfhydryl crosslinkers that differ in length from 17.6 to 95.2 angstroms as a result of polyethylene glycol spacer arms containing n equals 2 to 24 ethylene glycol units.

EGS (ethylene glycol bis(succinimidyl succinate)) Thermo Scientific™

Thermo Scientific Pierce EGS is a crosslinker that contains amine-reactive NHS-ester ends around a 12-atom spacer arm, which can be cleaved by treatment with hydroxylamine at pH 8.5. Features of the EGS crosslinker: • Reactive groups: NHS ester (both ends) • Reactive towards: amino groups (primary...

DST (disuccinimidyl tartrate) Thermo Scientific™

Thermo Scientific Pierce DST, also called disuccinimidyl tartrate, is a water-soluble crosslinker that contains amine-reactive NHS ester ends around a 4-atom spacer arm, whose central diol can be cleaved by periodate oxidation.

Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate)) Thermo Scientific™

Thermo Scientific Pierce Sulfo-EGS is a water-soluble crosslinker that contains amine-reactive sulfo-NHS-ester ends around a 12-atom spacer arm, which can be cleaved by treatment with hydroxylamine at pH 8.5.

LC-SPDP (succinimidyl 6-(3(2-pyridyldithio)propionamido)hexanoate) Thermo Scientific™

Thermo Scientific Pierce LC-SPDP is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

SPDP (succinimidyl 3-(2-pyridyldithio)propionate) Thermo Scientific™

Thermo Scientific Pierce SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

BS3-d0 (bis(sulfosuccinimidyl) suberate-d0) Thermo Scientific™

Thermo Scientific Pierce BS3-d0/d4 reagents form a matched set of heavy (deuterated) and light mass varieties of BS3 amine-reactive crosslinker that facilitates the identification of crosslinked peptides by mass spectrometry.
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