Protein Digestion Chromatography Sample Preparation Kits

Protein Digestion Chromatography Sample Preparation Kits

Pepsin & Protease XIII (1)
RNase A (1)
RNase T1 (1)
Trypsin (11)
None (10)
None (1)
C-terminal side of lysine and arginine amino acids (11)
Degrades single-stranded RNA at C & U residues (1)
Degrades single-stranded RNA at G residues (1)
Pepsin: Cleaves proteins preferentially at carboxylic groups of aromatic amino acids such as phenylalanine, tryptophan and tyrosine. The optimum pH range for pepsin activity is 1.0–3.0.

Protease XIII: Cleaves proteins preferentially at carboxylic groups of basic amino acids (arginine, lysine, histidine). Like pepsin, Proteinase XIII is active at low pH. (1)
SMART Digest Low pH Resin Pre-filled into PCR Tubes (1)
SMART Digest Resin Pre-filled into PCR Tubes (3)
SMART Digest Resin, Bulk Magnetic (3)
SMART Digest Resin, Bulk Non-magnetic (3)
SMART Digest Soluble Trypsin (1)
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SMART Digest™ Trypsin Kits
SMART Digest™ Trypsin Kits Thermo Scientific™
Obtain high quality analytical results from protein digests using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels...
SMART Digest RNase Columns
SMART Digest RNase Columns Thermo Scientific™
Thermo Scientific SMART Digest Immobilized Ribonucleases (Rnases) Columns are designed using the same proven technology as the Thermo Scientific SMART Digest Rnase kits to provide simple, fast and highly reproducible digestion of ribonucleic acid (RNA) in a flow through format.
SMART Digest™ Dual Enzyme Columns for HDX-MS Analysis
SMART Digest™ Dual Enzyme Columns for HDX-MS Analysis Thermo Scientific™
Thermo Scientific SMART Digest Dual Enzyme columns containing pepsin and protease XIII provide fast, reliable digestion of proteins for for HDX-MS analysis helping to provide the sequence characterization of biotherapeutics.
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Chromatography Sample Preparation
Sample preparation is a key step in analytical workflow. Our solutions include a multitude of consumables and automated platforms to enable fast, reproducible and easy sample preparation whatever your workflow requirements may be.
LC-MS Protein Sample Preparation Kits
Liquid chromatography-mass spectrometry (LC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) are key techniques in proteomic research studies. High-quality preparation of protein to peptide samples for LC-MS and LC-MS/MS is essential for high-quality results.
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Product FAQ
Can I use the AccelerOme TMT11plex MS Sample Preparation Kits and the AccelerOme TMTpro 16plex MS Sample Preparation Kits for samples with protein amounts lower than 10 µg?
Product FAQ
When using the AccelerOme TMT11plex MS Sample Preparation Kits and the AccelerOme TMTpro 16plex MS Sample Preparation Kits, should I add a protease inhibitor cocktail to the lysis buffer? How about phosphatase inhibitors?