Shop All Magnetic Beads Surface-Activated

Dynabeads™ MyOne™ Silane

An excellent tool for highly predictable and consistent extraction and isolation of nucleic acids from biological samples, following a simple magnetic separation protocol. Please note that this is a stand-alone product containing only Dynabeads® in a storage buffer. Our products Dynabeads® SILANE genomic DNA (Cat.no. 370-12D) or Dynabeads® SILANE viral NA (Cat.no. 370-11D) include the appropriate buffers and protocols you need to extract genomic DNA or viral nucleic acids respectively.

Magnetic particles from alternative suppliers often have a random size range distribution, surface area and binding capacity. This could compromise the reproducibility of your results. With Dynabeads® MyOne™ SILANE you are ensured a higher sensitivity, capacity and performance.

The small 1 µm Dynabeads® MyOne™ SILANE have an optimized silica-like surface chemistry and a high specific surface area, providing efficient kinetics and a high sensitivity in nucleic acid capture. Their uniform size and surface area also ensure reproducible results. The product holds reputable Dynal® high standards with respect to within- and between-lot reproducibility and automation ability.

Advantages:

• Highly predictable binding per mg of beads
• High sensitivity, allowing for a low detection limit
• For isolation of viral DNA⁄RNA, total RNA, genomic DNA, etc.
• Isolates both DNA and RNA
• Quicker than spin columns
• More cost-effective, yet performs to the same level as spin columns
• Automation-friendly (slow sedimentation rate + high magnetic mobility)
• Adjusted to customer requirements on a custom OEM basis

Applications:
• Isolation of total nucleic acids (DNA⁄RNA)from typical biological samples (e.g. serum⁄plasma, whole blood, etc.)
• Well suited for automated assays.
• Dedicated kits have been developed for isolation of viral nucleic acids and genomic DNA (available separately).

Additional Info:
Validation and customization (bead, buffer, protocol or format) can be made available on a custom OEM basis. For further information and price quotes for larger volumes of the silica-like Dynabeads® MyOne™ SILANE, please contact us at: ivd@invitrogen.com.

Pierce™ NHS-Activated Magnetic Beads (Thermo Scientific™)

Thermo Scientific Pierce NHS-Activated Magnetic Beads enable covalent, amine-based conjugation of proteins to magnetic beads in a simple mix-and-go format for use in custom affinity purification experiments.

Features of NHS-Activated Magnetic Beads:

High capacity—at least four times higher binding capacity than NHS-activated magnetic beads from other suppliers
Easy to use—immobilize in a simple one-step reaction with minimal hands-on time
• Safe—no hazardous chemicals needed (e.g., sodium cyanoborohydride and cyanogen bromide)
Ligand-compatible—use to immobilize with nearly any primary amine-containing compound or affinity ligand
Low non-specific binding—the bead surface is pre-blocked and any nonreacted NHS-ester groups are fully quenched
Protocol-compatible—protein coupling to the beads and downstream applications can be performed manually or by automation (e.g., Thermo Scientific KingFisher Instruments)

The activated magnetic beads contain N-hydroxy-succinimide (NHS) functional groups that react with primary amines forming stable amide linkages. Once they are covalently attached, the immobilized proteins are highly resistant to leaching from the bead surface. When prepared beads are used in experiments, nonspecific binding is negligible because nonreacted NHS-ester groups are thoroughly blocked during the coupling procedure. Pierce NHS-Activated Magnetic beads can be coupled and processed either manually with a magnetic stand or with automated platforms such as the Thermo Scientific KingFisher Instruments.

Applications:
• Immobilization of ligands for the purification of recombinant proteins
• Immobilization of antibodies for immunoprecipitations and co-immunoprecipitations free of antibody contamination in the eluates
• Immobilization of secondary antibody for the affinity purification of antibody subtypes from ascites, serum and cell culture supernatant

Pierce NHS-Activated Magnetic Beads offer a convenient way to conjugate any desired protein to a magnetic bead surface. The process does not require hazardous chemicals or lengthy reaction schemes. The beads are first incubated with protein for 1 to 2 hours in an amine free buffer at pH 7 to 9 to allow for covalent coupling through NHS-ester chemistry. The beads are subsequently washed and then any remaining active NHS-ester groups are quenched. The amine reactive chemistry and subsequent quench are completed in 3 to 4 hours. Coupled protein does not leach from the bead surface. In addition, the beads exhibit very low non-specific binding due to effective quenching and a proprietary blocking agent that coats the surface of the base particle. Following conjugation the prepared magnetic beads are typically used in affinity purification procedures.

Dynabeads™ MyOne™ Epoxy, for OEM and industrial use only

Dynabeads® MyOne™ Epoxy are monosized 1-µm superparamagnetic polystyrene beads coated with a cross-linked layer of hydrophilic polyether. Epoxy functional groups allow for covalent coupling of antibodies or other proteins, peptides, lectins, haptens, or functional enzymes onto a non-charged bead surface through amine or thiol groups with no further activation of the surface. No blocking protein is needed during the preparation, and standard assay diluents may be used. The Dynabeads®-ligand complex can be used for immunoassays or any other application requiring an active biomolecule conjugated to a magnetic solid support.

Dynabeads® magnetic beads are widely used as a solid-phase for presenting antibodies or antigens in automated clinical immunoassay systems, where the combination of specific antigens or antibodies and the superparamagnetic properties of the beads provide rapid reaction kinetics both in the coating process, separation, and during washing of the analyte.

The product is provided in a freeze-dried format and meets reputable Dynal high standards with respect to reproducibility and automation ability, and drives reliability for your assays.

Benefits:

• Efficient and reproducible immobilization of antibodies (or other ligands)
• Easy and reproducible handling in manufacturing
• Rapid separation and washing
• Reproducible behavior in automation
• Easy coupling without need for protein blocking
• Freeze-dried beads
• High activity of bound antibody and antigen
• Easy assay optimization
• Well-suited for binding of small antigens such as synthetic or recombinant peptides
• Generally low background and high signal-to-noise ratio

Applications
Ideally suited for immunoassay, with coupling of antibodies with optimal orientation for affinity purification of proteins and other antigens.

Note:
This specific product format is for large volume customers, available on an OEM basis only.

Dynabeads™ Co-Immunoprecipitation Kit (Invitrogen™)

Dynabeads® Co-Immunoprecipitation Kit allows easy coupling of an antibody of your choice to the surface of uniform, 2.8 µm superparamagnetic Dynabeads® M-270 Epoxy beads. Following immobilization of your antibody, use the coupled beads and the buffers supplied in the kit for co-immunoprecipitation (co-IP) of proteins, intact protein complexes, or intact protein-nucleic acid complexes and to elute those complexes from the beads. In addition to Dynabeads®, the kit supplies the buffers needed for efficient antibody coupling, gentle washing, and elution of the co-isolated protein complexes.

• Optimized buffers and Epoxy-coated Dynabeads® for efficient co-IP included in the kit
• Gentle separation technology: preserves native protein conformations and large-protein complexes
• Covalent antibody coupling to the Dynabeads® avoids co-elution of the antibody with the target proteins

Efficient, easy coupling
Antibodies are covalently coupled to Dynabeads® M-270 Epoxy beads, minimizing the risk of bound antibody contaminating your final eluate. Dynabeads® M-270 Epoxy beads exhibit ultra-low background binding and don't require blocking before use. The supplied buffers are optimized to give consistent and reliable results and the kit includes 8 different binding, washing, and elution buffers, in addition to Dynabeads® M-270 Epoxy to enable you to purify complex protein structures of any size. All kit components are analytical grade and are compatible with protease and phosphatase inhibitors. The only thing you need to supply is the antibody of choice. The protocol describes coupling, sample preparation (detergent and cryolysis methods), co-IP and elution, and is compatible with western blot/silver stain, Coomassie™ stain, mass spectrometry, or extraction of nucleic acids from isolated DNA/RNA binding protein complexes.

Magnetic bead-based separation offers easy handling
Captured proteins and protein complexes are easily separated, washed, and eluted using a DynaMag™ magnet, and the magnetic separation properties of the Dynabeads®. The kit is designed for and tested with cultured yeast and mammalian cells and is compatible with tissue, insect, bacteria, and othe lysates.

Learn more about Dynabeads® products
• Find Dynabeads® products for a whole range of applications.
• Find magnets for Dynabeads® separations.
• Dynabeads® M-270 Epoxy is also available as a stand-alone product, without the buffers supplied.

Dynabeads™ M-270 Epoxy, for OEM and industrial use only

Dynabeads® M-270 Epoxy are monosized 2.8-µm superparamagnetic polystyrene beads coated with a cross-linked layer of hydrophilic polyether. Epoxy functional groups allow for covalent coupling of antibodies or other proteins, peptides, lectins, haptens, or functional enzymes onto a non-charged bead surface through amine or thiol groups with no further activation of the surface. No blocking protein is needed during the preparation, and standard assay diluents may be used. The Dynabeads®-ligand complex can be used for immunoassays or any other application requiring an active biomolecule conjugated to a magnetic solid support.

Dynabeads® magnetic beads are widely used as a solid-phase for presenting antibodies or antigens in automated clinical immunoassay systems, where the combination of specific antigens or antibodies and the superparamagnetic properties of the beads provide rapid reaction kinetics both in the coating process, separation, and during washing of the analyte.

The product is provided in a freeze-dried format and meets reputable Dynal high standards with respect to reproducibility and automation ability, and drives reliability for your assays.

Benefits:

• Efficient and reproducible immobilization of antibodies (or other ligands)
• Easy and reproducible handling in manufacturing
• Rapid separation and washing
• Reproducible behavior in automation
• Easy coupling without need for protein blocking
• Freeze-dried beads
• High activity of bound antibody and antigen
• Easy assay optimization
• Well-suited for binding of small antigens such as synthetic or recombinant peptides
• Generally low background and high signal-to-noise ratio

Applications
Ideally suited for magnetic bead-based immunoassays requiring a low background signal. Also suited for any application involving immunoaffinity binding to antibody or antigen immobilized on a magnetic surface.

Note:
This particular product format is for large volume customers, available on an OEM basis. This product is also available in smaller volumes (14301D and 14302D).

Dynabeads™ M-270 Carboxylic Acid (Invitrogen™)

These are hydrophilic Dynabeads® (2.8 µm) with carboxylic acid groups. These surface groups allow covalent amide bond formation to proteins/peptides via primary amino- or sulphydryl groups.

• Immediate and gentle coupling at low temperature and neutral to low pH
• Activation through carbodiimide is required
• Alternative reactive groups can be introduced by using commercially available cross-linkers

Applications:
Ideal for isolation of small components such as proteins and peptides. Immobilization of labile proteins/peptides and N-terminal coupling of peptides. Low non-specific binding of nucleic acids.

Concentration:
2 × 109 beads / ml

Dynabeads™ M-270 Amine (Invitrogen™)

These are hydrophilic Dynabeads® (2.8 µm) with amine groups. The surface amino groups allow direct covalent binding of carbohydrates, glycoproteins and glycolipids through reductive amination of aldehydes.

• Rapid binding (less than 1 hour) at neutral to high pH and room temperature.
• No further surface activation required.
• Excellent reactivity with a range of cross-linking reagents, allowing for easy introduction of further alternative surface chemistries.

Applications:
Ideal for isolation of small components such as proteins and peptides. Allows C-terminal coupling of proteins. Well suited for isolation of proteins or other targets with affinity for specific carbohydrate moieties.

Concentration:
2 x 109 beads / ml

Dynabeads™ MyOne™ Tosylactivated (Invitrogen™)

When you wish to covalently couple antibodies, peptides, intact proteins, and functional enzymes to the surface of a magnetic bead choose Dynabeads® Tosylactivated. Optimal antibody orientation makes these beads an excellent choice for the immunoprecipitation of proteins and protein complexes.

Ideal for Immunoprecipitation of protein complexes:
Low background and covalent linking of antibodies to the bead surface make Dynabeads Tosylactivated an excellent choice for Immunoprecipitation of proteins and protein complexes (Co-Immunoprecipitation, Co-IP). Gentle and rapid magnetic concentration of the beads and short incubation times (possible due to fast surface-based binding kinetics) make Dynabeads Tosylactivated an excellent choice for the immunoprecipitation of highly-labile or and/or transient (short-lived) protein complexes.

Bead Surface Characteristics for Dynabeads Tosylactivated:

• p-toluene-sulfonyl (Tosyl) groups
• Hydrophobic, pH Neutral
• Covalent binding by primary amine (NH2) or sulphydryl (SH) groups

Ultra rapid protocols:
• Identify members of protein complexes in minutes rather than hours
• Temporal resolution short enough to identify transient and labile complexes
• Identify binding partners that cannot be identified with longer protocols
• Rapid protocols further reduce the already ultra-low background binding
• Stronger signal to noise-ratios

Applications:
• IP of proteins and protein complexes
• Couple functional enzymes to bead surface for downstream assays
• Couple peptides to bead surface to identify binders

Purify peptides, proteins and enzymes that are:
• Transiently stable
• Structurally intact
• Temperature labile
• In their native conformation and functional

Coupling procedure outline:
Covalent coupling is performed overnight by incubating the desired ligand with the Dynabeads Tosylactivated. Ligands commonly coupled to Dynabeads Tosylactivated include peptides and proteins (e.g. antibodies for Immunoprecipitation or Co-Immunoprecipitation). Coupling occurs at neutral to high pH and at 37°C. We recommend coupling at pH 8.5-9.5, but for pH labile ligands, coupling can be performed in an alternative buffer at pH 7.4.

Upon completion of the ligand coupling step, the actual Dynabeads Tosylactivated surface coating will be rendered inert, resulting in low non-specific binding.

Binding capacity per milligram beads:
Varies depending on ligand, (e.g. 14-19 µg IgG)

About Dynabeads:

Dynabeads are non-porous monodisperse superparamagnetic beads. They are highly mobile in solution enabling ligands coupled to the beads to continuously interact with the entire sample volume. The superparamagnetic beads are pulled to the tube walls by transferring the tube to a rack containing a strong magnetic field. Strong magnetic fields quickly pull the beads to the tube wall, allowing for easy and complete removal of the supernatant by pipette. Washing steps are performed similarly.

Dynabeads™ M-280 Tosylactivated (Invitrogen™)

When you wish to covalently couple antibodies, peptides, intact proteins and functional enzymes to the surface of a magnetic bead choose Dynabeads® Tosylactivated. Optimal antibody orientation makes these beads an excellent choice for the immunoprecipitation of proteins and protein complexes.

Ideal for Immunoprecipitation of protein complexes:
Low background and covalent linking of antibodies to the bead surface make Dynabeads Tosylactivated an excellent choice for Immunoprecipitation of proteins and protein complexes (Co-Immunoprecipitation, Co-IP). Gentle and rapid magnetic concentration of the beads and short incubation times (possible due to fast surface-based binding kinetics) make Dynabeads Tosylactivated an excellent choice for the immunoprecipitation of highly-labile or and/or transient (short-lived) protein complexes.

Ultra rapid protocols:

• Identify members of protein complexes in minutes rather than hours
• Temporal resolution short enough to identify transient and labile complexes
• Identify binding partners that cannot be identified with longer protocols
• Rapid protocols further reduce the already ultra-low background binding
• Stronger signal to noise-ratios

Applications:
• IP of proteins and protein complexes
• Couple functional enzymes to bead surface for downstream assays
• Couple peptides to bead surface to identify binders

Purify peptides, proteins and enzymes that are:
• Transiently stable
• Structurally intact
• Temperature labile
• In their native conformation and functional

Coupling procedure outline:
Covalent coupling is performed overnight by incubating the desired ligand with the Dynabeads Tosylactivated. Ligands commonly coupled to Dynabeads Tosylactivated include peptides and proteins (e.g. antibodies for Immunoprecipitation or Co-Immunoprecipitation). Coupling occurs at neutral to high pH and at 37°C. We recommend coupling at pH 8.5-9.5, but for pH labile ligands, coupling can be performed in an alternative buffer at pH 7.4.

Upon completion of the ligand coupling step, the actual Dynabeads Tosylactivated surface coating will be rendered inert, resulting in low non-specific binding.

About Dynabeads:
Dynabeads are non-porous monodisperse superparamagnetic beads. They are highly mobile in solution enabling ligands coupled to the beads to continuously interact with the entire sample volume. The superparamagnetic beads are pulled to the tube walls by transferring the tube to a rack containing a strong magnetic field (From the red navigation bar navigate Brands > Dynal® > Magnets). Strong magnetic fields quickly pull the beads to the tube wall, allowing for easy and complete removal of the supernatant by pipette. Washing steps are performed similarly.

Bead Surface Characteristics for Dynabeads Tosylactivated:
• p-toluene-sulfonyl (Tosyl) groups
• Hydrophobic, pH Neutral
• Covalent binding by primary amine (NH2) or sulphydryl (SH) groups

Binding capacity per milligram beads:
Varies depending on ligand, (e.g. 5-10 µg IgG)

MagnaBind™ Carboxyl Derivatized Beads (Thermo Scientific™)

Thermo Scientific™ MagnaBind™ Beads provide a convenient method for magnetic separation of antibodies, antigens, lectins, enzymes, nucleic acids and cells using affinity binding. To remove the MagnaBind Beads from the suspension, an external magnetic field is used.

MagnaBind Carboxyl Derivatized Beads are supplied as an aqueous suspension of magnetic iron oxide beads coated with carboxyl groups for covalent coupling of molecules using EDC, a zero-length crosslinker that is amine- and carboxyl-reactive. Additionally, carboxyl derivatized beads have been used to purify plasmid DNA from cells.

Features of MagnaBind Carboxyl Derivatized Beads:

Composition: Silanized iron oxide
Magnetization: 25-35EMU/g
Type of Magnetization: Superparamagnetic (no magnetic memory)
Surface Area: >100m2/g
Bead Size: 1-4µm diameter
Settling Rate: 4% in 30 minutes
Effective Density: 2.5g/mL
Number of Beads: 1 × 108 beads/mg
pH Stability: Aqueous solution, above pH 4.0
Concentration: ~20 mg/mL

Applications:
• Cell sorting using either positive or negative selection
• Protein purification or immunoassays using either direct or indirect methods

Dynabeads™ M-270 Carboxylic Acid, for OEM and industrial use only

Dynabeads® M-270 Carboxylic Acid are monosized hydrophilic 2.8-µm superparamagnetic beads, composed of highly crosslinked polystyrene. Carboxylic acid groups on the surface allow for covalent amide bond formation to nucleic acids, proteins?peptides, and other ligands via primary amino- or sulphydryl groups, without requirement for protein blocking. Activation through carbodiimide is required and alternative reactive groups can be introduced by using commercially available cross-linkers.

Dynabeads® magnetic beads are widely used as a solid-phase for presenting antibodies or antigens in automated clinical immunoassay systems, where the combination of specific antigens or antibodies and the superparamagnetic properties of the beads provide rapid reaction kinetics both in the coating process, separation, and during washing of the analyte.

The product meets the reputable Dynal high standards with respect to reproducibility and automation ability, and drives reliability for your assays.

Benefits:

• Efficient and reproducible immobilization of antibodies (or other ligands)
• Easy and reproducible handling in manufacturing
• Rapid separation and washing
• Reproducible behavior in automation without mixing requirements, with fast and efficient washing procedures
• Fast coupling without need for protein blocking
• Generally low background and high signal-to-noise ratio

Applications
Ideally suited for magnetic bead-based immunoassays requiring a low background signal.

Note:
This particular product format is for large volume customers, available on an OEM basis. This product is also available in smaller volumes (14306D and 14305D).

Dynabeads™ Antibody Coupling Kit (Invitrogen™)

Dynabeads® Antibody Coupling Kit allows easy coupling of an antibody of your choice to the surface of uniform, 2.8 µm superparamagnetic Dynabeads® M-270 Epoxy beads. Following immobilization of your antibody, the beads can then be used for experiments such as immunoassays, immunoprecipitation (IP), co-immunoprecipitation (co-IP) of protein complexes, co-IP of protein-nucleic acid complexes, as well as many other downstream applications. The Dynabeads® Epoxy beads in this kit do not contain Tween® detergent, and so are ideal for use in mass spectrometry (MS) analysis. In addition to Dynabeads®, the kit supplies all buffers needed for the coupling and washing steps. Note that the SB buffer supplied in the kit contains Tween® detergent, so the SB buffer will need to be replaced with standard TBS or PBS buffer if the kit is to be used for MS.

• Optimized buffers and Epoxy-coated Dynabeads® included in the kit
• Easy-to-use protocol with minimal hands-on time
• Covalent antibody coupling to the Dynabeads® avoids co-elution of the antibody with the target protein

Efficient, easy coupling
Antibodies are covalently coupled to Dynabeads® M-270 Epoxy beads, minimizing the risk of bound antibody contaminating your final eluate. Dynabeads® M-270 Epoxy beads exhibit ultra-low background binding and don't require blocking before use. Other proteins such as lectins and enzymes may also be coupled using the same beads, buffers, and protocol (depending on the stability and functionality of the protein/ligand you are using).

Magnetic bead-based separation offers easy handling
Captured proteins and protein complexes are easily separated, washed, and eluted using a DynaMag™ magnet and the magnetic separation properties of the Dynabeads® . The supplied buffers are optimized to give consistent and reliable results and the kit includes 5 different binding, washing, and elution buffers, in addition to Dynabeads® M-270 Epoxy. The only thing you need to supply is the antibody of choice.

Learn more about Dynabeads® products

• Dynabeads® M-270 Epoxy can also be purchased as a separate product, without the buffers.
• Find Dynabeads® products for a whole range of applications.
• Find magnets for Dynabeads® separations.

MagnaBind™ Amine Derivatized Beads (Thermo Scientific™)

Thermo Scientific™ MagnaBind™ Beads provide a convenient method for magnetic separation of antibodies, antigens, lectins, enzymes, nucleic acids and cells using affinity binding. To remove the MagnaBind Beads from the suspension, an external magnetic field is used.

MagnaBind Amine Derivatized Beads are supplied as an aqueous suspension of magnetic iron oxide beads coated with amine groups for covalent coupling of molecules using a variety of crosslinkers.

Features of MagnaBind Amine Derivatized Beads:

Composition: Silanized iron oxide
Magnetization: 25-35EMU/g
Type of Magnetization: Superparamagnetic (no magnetic memory)
Surface Area: >100m2/g
Bead Size: 1-4µm diameter
Settling Rate: 4% in 30 minutes
Effective Density: 2.5g/mL
Number of Beads: 1 × 108 beads/mg
pH Stability: Aqueous solution, above pH 4.0
Concentration: ~50 mg/mL

Applications:
• Cell sorting using either positive or negative selection
• Protein purification or immunoassays using either direct or indirect methods

Dynabeads™ M-270 Epoxy (Invitrogen™)

Dynabeads® M-270 Epoxy beads are 2.8 µm superparamagnetic beads containing surface epoxy groups. The beads covalently bind primary amino and sulfhydryl groups in proteins and peptides, making them ideal for coupling antibodies, peptides, intact proteins, and functional enzymes. These hydrophylic, neutral pH beads exhibit extremely low nonspecific binding of proteins and dyes, which reduces the need for blocking agents. Also, Dynabeads® M-270 Epoxy Beads do not contain Tween® detergent, and so are ideal for use in mass spectrometry (MS) analysis.

• Ideal for immunoprecipitation (IP) of proteins and protein complexes
• Gentle, yet rapid magnetic separation and short incubation times allow identification of transient and labile complexes
• Covalent antibody-coupling to the Dynabeads® avoids co-elution of the antibody with the target protein

Adaptable for various applications
Fast surface binding kinetics and rapid magnetic separation characteristics make Dynabeads® M-270 Epoxy beads the ideal choice for applications such as immunoprecipitation/purification of proteins and protein complexes, coupling functional enzymes to the bead surface for downstream assays, and identifying protein binding partners. Captured proteins and protein complexes are easily separated, washed, and eluted using a DynaMag™ magnet, and the magnetic separation properties of the Dynabeads® .

Coupling procedure
Covalent coupling is performed overnight by incubating the desired ligand (commonly antibodies, peptides, or proteins) with Dynabeads® M-270 Epoxy beads. The binding capacity varies depending on the ligand used, but is typically 5–10 µg IgG per milligram of beads. Coupling occurs at neutral pH and high salt concentration. The coupling reaction can be performed over a broad range of temperatures to match the stability characteristics of your ligand.

Upon completion of the ligand coupling step, the reactive moieties on the Dynabeads® M-270 Epoxy beads are deactivated to prevent further coupling. Once the coupling reaction is completed, these nonporous, hydrophilic, pH neutral beads exhibit extremely low nonspecific binding.

Learn More about Dynabeads® Products
• Find Dynabeads® products for a whole range of applications.
• Find magnets for Dynabeads® separations.

Dynabeads™ MyOne™ Carboxylic Acid (Invitrogen™)

Surface carboxylic acid groups allow covalent amide bond formation to proteins/peptides via primary amino- or sulphydryl groups. Rapid binding chemistry, activation through carbodimide is required. Amino-modified oligonucleotides, antibodies or other ligands can easily be coupled to the beads. Low non-specific binding of nucleic acids. The 1 µm Dynabeads® MyOne™ have a large surface area, high capacity, efficient magnetic pull and a slow sedimentation rate during incubation. The MyOne™ products are tailor-made for use in automated protocols where high throughput is crucial.

Benefits and Features:

Ideal for use as a solid support in in vitro diagnostic assays.

• Capture of specific DNA/RNA sequences, proteins or any other analyte.
• High magnetic mobility and low sedimentation rate

Concentration:
10 mg/ml